Glucocorticoid signaling in pancreatic islets modulates gene regulatory programs and genetic risk of type 2 diabetes

por Aylward, Anthony, Okino, Mei-Lin, Benaglio, Paola, Chiou, Joshua, Beebe, Elisha, Padilla, Jose Andres, Diep, Sharlene, Gaulton, Kyle J.
Publicado 2021

Type 1 diabetes risk genes mediate pancreatic beta cell survival in response to proinflammatory cytokines

por Benaglio, Paola, Zhu, Han, Okino, Mei-Lin, Yan, Jian, Elgamal, Ruth, Nariai, Naoki, Beebe, Elisha, Korgaonkar, Katha, Qiu, Yunjiang, Donovan, Margaret K.R., Chiou, Joshua, Wang, Gaowei, Newsome, Jacklyn, Kaur, Jaspreet, Miller, Michael, Preissl, Sebastian, Corban, Sierra, Aylward, Anthony, Taipale, Jussi, Ren, Bing, Frazer, Kelly A., Sander, Maike, Gaulton, Kyle J.
Publicado 2022

Integration of single-cell multiomic measurements across disease states with genetics identifies mechanisms of beta cell dysfunction in type 2 diabetes

por Wang, Gaowei, Chiou, Joshua, Zeng, Chun, Miller, Michael, Matta, Ileana, Han, Jee Yun, Kadakia, Nikita, Okino, Mei-Lin, Beebe, Elisha, Mallick, Medhavi, Camunas-Soler, Joan, dos Santos, Theodore, Dai, Xiao-Qing, Ellis, Cara, Hang, Yan, Kim, Seung K., MacDonald, Patrick E., Kandeel, Fouad R., Preissl, Sebastian, Gaulton, Kyle J, Sander, Maike
Publicado 2023