Identifying the genomic determinants of aging and longevity in human population studies: Progress and challenges

por Deelen, Joris, Beekman, Marian, Capri, Miriam, Franceschi, Claudio, Slagboom, P Eline
Publicado 2013

Genotype-Based Score Test for Association Testing in Families

por Uh, Hae-Won, Beekman, Marian, Meulenbelt, Ingrid, Houwing-Duistermaat, Jeanine J.
Publicado 2015

Improved selection of participants in genetic longevity studies: family scores revisited

por Rodríguez-Girondo, Mar, van den Berg, Niels, Hof, Michel H., Beekman, Marian, Slagboom, Eline
Publicado 2021

Gut microbiome changes due to sleep disruption in older and younger individuals: a case for sarcopenia?

por Morwani-Mangnani, Jordi, Giannos, Panagiotis, Belzer, Clara, Beekman, Marian, Eline Slagboom, P, Prokopidis, Konstantinos
Publicado 2022

Assessment of the contribution of APOE gene variants to metabolic phenotypes associated with familial longevity at middle age

por Noordam, Raymond, Oudt, Charlotte H., Deelen, Joris, Slagboom, P. Eline, Beekman, Marian, van Heemst, Diana
Publicado 2016

Increasing number of long-lived ancestors marks a decade of healthspan extension and healthier metabolomics profiles

por van den Berg, Niels, Rodríguez-Girondo, Mar, van Dijk, Ingrid K., Slagboom, P. Eline, Beekman, Marian
Publicado 2023

Metabolomic and lipidomic assessment of the metabolic syndrome in Dutch middle-aged individuals reveals novel biological signatures separating health and disease

por Surowiec, Izabella, Noordam, Raymond, Bennett, Kate, Beekman, Marian, Slagboom, P. Eline, Lundstedt, Torbjörn, van Heemst, Diana
Publicado 2019

Longevity Relatives Count score identifies heritable longevity carriers and suggests case improvement in genetic studies

por van den Berg, Niels, Rodríguez‐Girondo, Mar, Mandemakers, Kees, Janssens, Angelique A. P. O., Beekman, Marian, Slagboom, P. Eline
Publicado 2020

Relative validity of the food frequency questionnaire used to assess dietary intake in the Leiden Longevity Study

por Streppel, Martinette T, de Vries, Jeanne HM, Meijboom, Saskia, Beekman, Marian, de Craen, Anton JM, Slagboom, P Eline, Feskens, Edith JM
Publicado 2013

Longevity Around the Turn of the 20th Century: Life-Long Sustained Survival Advantage for Parents of Today’s Nonagenarians

por van den Berg, Niels, Rodríguez-Girondo, Mar, de Craen, Anton J M, Houwing-Duistermaat, Jeanine J, Beekman, Marian, Slagboom, P Eline
Publicado 2018

Fibroblast growth factor 21 reflects liver fat accumulation and dysregulation of signalling pathways in the liver of C57BL/6J mice

por Rusli, Fenni, Deelen, Joris, Andriyani, Evi, Boekschoten, Mark V., Lute, Carolien, van den Akker, Erik B., Müller, Michael, Beekman, Marian, Steegenga, Wilma T
Publicado 2016

Subclass-specific IgG glycosylation is associated with markers of inflammation and metabolic health

por Plomp, Rosina, Ruhaak, L. Renee, Uh, Hae-Won, Reiding, Karli R., Selman, Maurice, Houwing-Duistermaat, Jeanine J., Slagboom, P. Eline, Beekman, Marian, Wuhrer, Manfred
Publicado 2017

Fast LC-ESI-MS/MS analysis and influence of sampling conditions for gut metabolites in plasma and serum

por van der Laan, Tom, Kloots, Tim, Beekman, Marian, Kindt, Alida, Dubbelman, Anne-Charlotte, Harms, Amy, van Duijn, Cornelia M., Slagboom, P. Eline, Hankemeier, Thomas
Publicado 2019

Classification for Longevity Potential: The Use of Novel Biomarkers

por Beekman, Marian, Uh, Hae-Won, van Heemst, Diana, Wuhrer, Manfred, Ruhaak, L. Renee, Gonzalez-Covarrubias, Vanessa, Hankemeier, Thomas, Houwing-Duistermaat, Jeanine J., Slagboom, P. Eline
Publicado 2016

Thyroid status and mortality in nonagenarians from long-lived families and the general population

por van Vliet, Nicolien A., van der Spoel, Evie, Beekman, Marian, Slagboom, P. Eline, Blauw, Gerard Jan, Gussekloo, Jacobijn, Westendorp, Rudi G.J., van Heemst, Diana
Publicado 2017

C-reactive protein and glucose regulation in familial longevity

por Rozing, Maarten P., Mooijaart, Simon P., Beekman, Marian, Wijsman, Carolien A., Maier, Andrea B., Bartke, Andrzej, Westendorp, Rudi G.J., Slagboom, Eline P., van Heemst, Diana
Publicado 2011

Lipoprotein Particle Profiles Mark Familial and Sporadic Human Longevity

por Heijmans, Bastiaan T, Beekman, Marian, Houwing-Duistermaat, Jeanine J, Cobain, Mark R, Powell, Jonathan, Blauw, Gerard Jan, van der Ouderaa, Frans, Westendorp, Rudi G. J, Slagboom, P. Eline
Publicado 2006

Copy number variation associates with mortality in long‐lived individuals: a genome‐wide assessment

por Nygaard, Marianne, Debrabant, Birgit, Tan, Qihua, Deelen, Joris, Andersen‐Ranberg, Karen, de Craen, Anton J.M., Beekman, Marian, Jeune, Bernard, Slagboom, Pieternella E., Christensen, Kaare, Christiansen, Lene
Publicado 2015

The effect of standardized food intake on the association between BMI and (1)H-NMR metabolites

por Schutte, Bianca A. M., van den Akker, Erik B., Deelen, Joris, van de Rest, Ondine, van Heemst, Diana, Feskens, Edith J. M., Beekman, Marian, Slagboom, P. Eline
Publicado 2016

Metabolomics analyses in non-diabetic middle-aged individuals reveal metabolites impacting early glucose disturbances and insulin sensitivity

por Bos, Maxime M., Noordam, Raymond, Bennett, Kate, Beekman, Marian, Mook-Kanamori, Dennis O., Willems van Dijk, Ko, Slagboom, P. Eline, Lundstedt, Torbjörn, Surowiec, Izabella, van Heemst, Diana
Publicado 2020