The major role of sarA in limiting Staphylococcus aureus extracellular protease production in vitro is correlated with decreased virulence in diverse clinical isolates in osteomyel...

por Campbell, Mara J., Beenken, Karen E., Ramirez, Aura M., Smeltzer, Mark S.
Publicado 2023

Factors Contributing to the Biofilm-Deficient Phenotype of Staphylococcus aureus sarA Mutants

por Tsang, Laura H., Cassat, James E., Shaw, Lindsey N., Beenken, Karen E., Smeltzer, Mark S.
Publicado 2008

The Staphylococcal Accessory Regulator, SarA, is an RNA-Binding Protein that Modulates the mRNA Turnover Properties of Late-Exponential and Stationary Phase Staphylococcus aureus C...

por Morrison, John M., Anderson, Kelsi L., Beenken, Karen E., Smeltzer, Mark S., Dunman, Paul M.
Publicado 2012

The Impacts of msaABCR on sarA-Associated Phenotypes Are Different in Divergent Clinical Isolates of Staphylococcus aureus

por Rom, Joseph S., Ramirez, Aura M., Beenken, Karen E., Sahukhal, Gyan S., Elasri, Mohamed O., Smeltzer, Mark S.
Publicado 2020

Limiting protease production plays a key role in the pathogenesis of the divergent clinical isolates of Staphylococcus aureus LAC and UAMS-1

por Rom, Joseph S., Beenken, Karen E., Ramirez, Aura M., Walker, Christopher M., Echols, Ethan J., Smeltzer, Mark S.
Publicado 2021

Ellagic Acid Derivatives from Rubus ulmifolius Inhibit Staphylococcus aureus Biofilm Formation and Improve Response to Antibiotics

por Quave, Cassandra L., Estévez-Carmona, Miriam, Compadre, Cesar M., Hobby, Gerren, Hendrickson, Howard, Beenken, Karen E., Smeltzer, Mark S.
Publicado 2012

Impact of individual extracellular proteases on Staphylococcus aureus biofilm formation in diverse clinical isolates and their isogenic sarA mutants

por Loughran, Allister J, Atwood, Danielle N, Anthony, Allison C, Harik, Nada S, Spencer, Horace J, Beenken, Karen E, Smeltzer, Mark S
Publicado 2014

SarA plays a predominant role in controlling the production of extracellular proteases in the diverse clinical isolates of Staphylococcus aureus LAC and UAMS-1

por Ramirez, Aura M., Beenken, Karen E., Byrum, Stephanie D., Tackett, Alan J., Shaw, Lindsey N., Gimza, Brittney D., Smeltzer, Mark S.
Publicado 2020

Impact of Staphylococcus aureus regulatory mutations that modulate biofilm formation in the USA300 strain LAC on virulence in a murine bacteremia model

por Rom, Joseph S., Atwood, Danielle N., Beenken, Karen E., Meeker, Daniel G., Loughran, Allister J., Spencer, Horace J., Lantz, Tamara L., Smeltzer, Mark S.
Publicado 2017

saeRS and sarA Act Synergistically to Repress Protease Production and Promote Biofilm Formation in Staphylococcus aureus

por Mrak, Lara N., Zielinska, Agnieszka K., Beenken, Karen E., Mrak, Ian N., Atwood, Danielle N., Griffin, Linda M., Lee, Chia Y., Smeltzer, Mark S.
Publicado 2012

In Vivo Magnetic Enrichment, Photoacoustic Diagnosis, and Photothermal Purging of Infected Blood Using Multifunctional Gold and Magnetic Nanoparticles

por Galanzha, Ekaterina I., Shashkov, Evgeny, Sarimollaoglu, Mustafa, Beenken, Karen E., Basnakian, Alexei G., Shirtliff, Mark E., Kim, Jin-Woo, Smeltzer, Mark S., Zharov, Vladimir P.
Publicado 2012

Evaluation of a chitosan-polyethylene glycol paste as a local antibiotic delivery device

por Rhodes, Cheyenne S, Alexander, Christopher M, Berretta, Joel M, Courtney, Harry S, Beenken, Karen E, Smeltzer, Mark S, Bumgardner, Joel D, Haggard, Warren O, Jennings, J Amber
Publicado 2017

Exploiting Correlations between Protein Abundance and the Functional Status of saeRS and sarA To Identify Virulence Factors of Potential Importance in the Pathogenesis of Staphyloc...

por Ramirez, Aura M., Byrum, Stephanie D., Beenken, Karen E., Washam, Charity, Edmondson, Rick D., Mackintosh, Samuel G., Spencer, Horace J., Tackett, Alan J., Smeltzer, Mark S.
Publicado 2019

Epistatic Relationships between sarA and agr in Staphylococcus aureus Biofilm Formation

por Beenken, Karen E., Mrak, Lara N., Griffin, Linda M., Zielinska, Agnieszka K., Shaw, Lindsey N., Rice, Kelly C., Horswill, Alexander R., Bayles, Kenneth W., Smeltzer, Mark S.
Publicado 2010

Label-Free Proteomic Approach to Characterize Protease-Dependent and -Independent Effects of sarA Inactivation on the Staphylococcus aureus Exoproteome

por Byrum, Stephanie D., Loughran, Allister J., Beenken, Karen E., Orr, Lisa M., Storey, Aaron J., Mackintosh, Samuel G., Edmondson, Ricky D., Tackett, Alan J., Smeltzer, Mark S.
Publicado 2018

Comparative impact of diverse regulatory loci on Staphylococcus aureus biofilm formation

por Atwood, Danielle N, Loughran, Allister J, Courtney, Ashleah P, Anthony, Allison C, Meeker, Daniel G, Spencer, Horace J, Gupta, Ravi Kr, Lee, Chia Y, Beenken, Karen E, Smeltzer, Mark S
Publicado 2015

Evaluation of Dynamic [(18)F]-FDG-PET Imaging for the Detection of Acute Post-Surgical Bone Infection

por Brown, Tracy L. Y., Spencer, Horace J., Beenken, Karen E., Alpe, Terri L., Bartel, Twyla B., Bellamy, William, Gruenwald, J. Michael, Skinner, Robert A., McLaren, Sandra G., Smeltzer, Mark S.
Publicado 2012

Synergistic Photothermal and Antibiotic Killing of Biofilm-Associated Staphylococcus aureus Using Targeted Antibiotic-Loaded Gold Nanoconstructs

por Meeker, Daniel G., Jenkins, Samir V., Miller, Emily K., Beenken, Karen E., Loughran, Allister J., Powless, Amy, Muldoon, Timothy J., Galanzha, Ekaterina I., Zharov, Vladimir P., Smeltzer, Mark S., Chen, Jingyi
Publicado 2016

Evaluation of a bone filler scaffold for local antibiotic delivery to prevent Staphylococcus aureus infection in a contaminated bone defect

por Beenken, Karen E., Campbell, Mara J., Ramirez, Aura M., Alghazali, Karrar, Walker, Christopher M., Jackson, Bailey, Griffin, Christopher, King, William, Bourdo, Shawn E., Rifkin, Rebecca, Hecht, Silke, Meeker, Daniel G., Anderson, David E., Biris, Alexandru S., Smeltzer, Mark S.
Publicado 2021

Small Molecule Inhibitors of Staphylococcus aureus RnpA Alter Cellular mRNA Turnover, Exhibit Antimicrobial Activity, and Attenuate Pathogenesis

por Olson, Patrick D., Kuechenmeister, Lisa J., Anderson, Kelsi L., Daily, Sonja, Beenken, Karen E., Roux, Christelle M., Reniere, Michelle L., Lewis, Tami L., Weiss, William J., Pulse, Mark, Nguyen, Phung, Simecka, Jerry W., Morrison, John M., Sayood, Khalid, Asojo, Oluwatoyin A., Smeltzer, Mark S., Skaar, Eric P., Dunman, Paul M.
Publicado 2011