Defining the clinical genomic landscape for real-world precision oncology

por Beer, Philip A., Cooke, Susanna L., Chang, David K., Biankin, Andrew V.
Publicado 2020

Germline Aberrations in Pancreatic Cancer: Implications for Clinical Care

por Casolino, Raffaella, Corbo, Vincenzo, Beer, Philip, Hwang, Chang-il, Paiella, Salvatore, Silvestri, Valentina, Ottini, Laura, Biankin, Andrew V.
Publicado 2022

Differential roles of CTP synthetases CTPS1 and CTPS2 in cell proliferation

por Minet, Norbert, Boschat, Anne-Claire, Lane, Rebecca, Laughton, David, Beer, Philip, Asnagli, Hélène, Soudais, Claire, Bourne, Tim, Fischer, Alain, Martin, Emmanuel, Latour, Sylvain
Publicado 2023

Targeting MEK in vemurafenib-resistant hairy cell leukemia

por Caeser, Rebecca, Collord, Grace, Yao, Wen-Qing, Chen, Zi, Vassiliou, George S., Beer, Philip A., Du, Ming-Qing, Scott, Mike A., Follows, George A., Hodson, Daniel J.
Publicado 2018

CTP Synthase 1 Is a Novel Therapeutic Target in Lymphoma

por Asnagli, Hélène, Minet, Norbert, Pfeiffer, Christina, Hoeben, Eef, Lane, Rebecca, Laughton, David, Birch, Louise, Jones, Geraint, Novak, Andrew, Parker, Andrew E., Ludwig, Heinz, Fischer, Alain, Latour, Sylvain, Beer, Philip A.
Publicado 2023

A Dominant-Negative Isoform of IKAROS Expands Primitive Normal Human Hematopoietic Cells

por Beer, Philip A., Knapp, David J.H.F., Kannan, Nagarajan, Miller, Paul H., Babovic, Sonja, Bulaeva, Elizabeth, Aghaeepour, Nima, Rabu, Gabrielle, Rostamirad, Shabnam, Shih, Kingsley, Wei, Lisa, Eaves, Connie J.
Publicado 2014

Analysis of parameters that affect human hematopoietic cell outputs in mutant c-kit-immunodeficient mice

por Miller, Paul H., Rabu, Gabrielle, MacAldaz, Margarita, Knapp, David J.H.F., Cheung, Alice M.S., Dhillon, Kiran, Nakamichi, Naoto, Beer, Philip A., Shultz, Leonard D., Humphries, R. Keith, Eaves, Connie J.
Publicado 2017

Epigenetic and functional changes imposed by NUP98-HOXA9 in a genetically engineered model of chronic myeloid leukemia progression

por Sloma, Ivan, Beer, Philip, Desterke, Christophe, Bulaeva, Elizabeth, Bilenky, Misha, Carles, Annaïck, Moksa, Michelle, Raghuram, Kamini, Brimacombe, Cedric, Lambie, Karen, Turhan, Ali G., Wagner-Ballon, Orianne, Gaulard, Philippe, Humphries, Keith, Hirst, Martin, Eaves, Connie J.
Publicado 2020

Dissociation of Survival, Proliferation, and State Control in Human Hematopoietic Stem Cells

por Knapp, David J.H.F., Hammond, Colin A., Miller, Paul H., Rabu, Gabrielle M., Beer, Philip A., Ricicova, Marketa, Lecault, Véronique, Da Costa, Daniel, VanInsberghe, Michael, Cheung, Alice M., Pellacani, Davide, Piret, James, Hansen, Carl, Eaves, Connie J.
Publicado 2017

Homologous Recombination Deficiency in Pancreatic Cancer: A Systematic Review and Prevalence Meta-Analysis

por Casolino, Raffaella, Paiella, Salvatore, Azzolina, Danila, Beer, Philip A., Corbo, Vincenzo, Lorenzoni, Giulia, Gregori, Dario, Golan, Talia, Braconi, Chiara, Froeling, Fieke E. M., Milella, Michele, Scarpa, Aldo, Pea, Antonio, Malleo, Giuseppe, Salvia, Roberto, Bassi, Claudio, Chang, David K., Biankin, Andrew V.
Publicado 2021

Cell Fate Decisions in Malignant Hematopoiesis: Leukemia Phenotype Is Determined by Distinct Functional Domains of the MN1 Oncogene

por Lai, Courteney K., Moon, Yeonsook, Kuchenbauer, Florian, Starzcynowski, Daniel T., Argiropoulos, Bob, Yung, Eric, Beer, Philip, Schwarzer, Adrian, Sharma, Amit, Park, Gyeongsin, Leung, Malina, Lin, Grace, Vollett, Sarah, Fung, Stephen, Eaves, Connie J., Karsan, Aly, Weng, Andrew P., Humphries, R. Keith, Heuser, Michael
Publicado 2014

Molecular subclusters of follicular lymphoma: a report from the United Kingdom’s Haematological Malignancy Research Network

por Crouch, Simon, Painter, Daniel, Barrans, Sharon L., Roman, Eve, Beer, Philip A., Cooke, Susanna L., Glover, Paul, Van Hoppe, Suzan J.L., Webster, Nichola, Lacy, Stuart E., Ruiz, Camilo, Campbell, Peter J., Hodson, Daniel J., Patmore, Russell, Burton, Cathy, Smith, Alexandra, Tooze, Reuben M.
Publicado 2022

Cardiopulmonary function in two human disorders of the hypoxia-inducible factor (HIF) pathway: von Hippel-Lindau disease and HIF-2α gain-of-function mutation

por Formenti, Federico, Beer, Philip A., Croft, Quentin P. P., Dorrington, Keith L., Gale, Daniel P., Lappin, Terence R. J., Lucas, Guy S., Maher, Eamonn R., Maxwell, Patrick H., McMullin, Mary F., O'Connor, David F., Percy, Melanie J., Pugh, Christopher W., Ratcliffe, Peter J., Smith, Thomas G., Talbot, Nick P., Robbins, Peter A.
Publicado 2011

Genetic modification of primary human B cells to model high-grade lymphoma

por Caeser, Rebecca, Di Re, Miriam, Krupka, Joanna A., Gao, Jie, Lara-Chica, Maribel, Dias, João M. L., Cooke, Susanna L., Fenner, Rachel, Usheva, Zelvera, Runge, Hendrik F. P., Beer, Philip A., Eldaly, Hesham, Pak, Hyo-Kyung, Park, Chan-Sik, Vassiliou, George S., Huntly, Brian J. P., Mupo, Annalisa, Bashford-Rogers, Rachael J. M., Hodson, Daniel J.
Publicado 2019

Cooperativity of imprinted genes inactivated by acquired chromosome 20q deletions

por Aziz, Athar, Baxter, E Joanna, Edwards, Carol, Cheong, Clara Yujing, Ito, Mitsuteru, Bench, Anthony, Kelley, Rebecca, Silber, Yvonne, Beer, Philip A, Chng, Keefe, Renfree, Marilyn B, McEwen, Kirsten, Gray, Dionne, Nangalia, Jyoti, Mufti, Ghulam J, Hellstrom-Lindberg, Eva, Kiladjian, Jean-Jacques, McMullin, Mary Frances, Campbell, Peter J, Ferguson-Smith, Anne C, Green, Anthony R
Publicado 2013

Prediction of acute myeloid leukaemia risk in healthy individuals

por Abelson, Sagi, Collord, Grace, Ng, Stanley W.K., Weissbrod, Omer, Cohen, Netta Mendelson, Niemeyer, Elisabeth, Barda, Noam, Zuzarte, Philip C., Heisler, Lawrence, Sundaravadanam, Yogi, Luben, Robert, Hayat, Shabina, Wang, Ting Ting, Zhao, Zhen, Cirlan, Iulia, Pugh, Trevor J., Soave, David, Ng, Karen, Latimer, Calli, Hardy, Claire, Raine, Keiran, Jones, David, Hoult, Diana, Britten, Abigail, McPherson, John D., Johansson, Mattias, Mbabaali, Faridah, Eagles, Jenna, Miller, Jessica, Pasternack, Danielle, Timms, Lee, Krzyzanowski, Paul, Awadalla, Phillip, Costa, Rui, Segal, Eran, Bratman, Scott V., Beer, Philip, Behjati, Sam, Martincorena, Inigo, Wang, Jean C.Y., Bowles, Kristian M., Quirós, J Ramón, Karakatsani, Anna, La Vecchia, Carlo, Trichopoulou, Antonia, Salamanca-Fernández, Elena, Huerta, José M., Barricarte, Aurelio, Travis, Ruth C., Tumino, Rosario, Masala, Giovanna, Boeing, Heiner, Panico, Salvatore, Kaaks, Rudolf, Krämer, Alwin, Sieri, Sabina, Riboli, Elio, Vineis, Paolo, Foll, Matthieu, McKay, James, Polidoro, Silvia, Sala, Núria, Khaw, Kay-Tee, Vermeulen, Roel, Campbell, Peter J, Papaemmanuil, Elli, Minden, Mark D, Tanay, Amos, Balicer, Ran D, Wareham, Nicholas J, Gerstung, Moritz, Dick, John E., Brennan, Paul, Vassiliou, George S., Shlush, Liran I.
Publicado 2018