The importance of using public data to validate reported associations

por Chenevix-Trench, Georgia, Beesley, Jonathan, Pharoah, Paul D. P., Berchuck, Andrew
Publicado 2018

SNPs in lncRNA Regions and Breast Cancer Risk

por Suvanto, Maija, Beesley, Jonathan, Blomqvist, Carl, Chenevix-Trench, Georgia, Khan, Sofia, Nevanlinna, Heli
Publicado 2020

Redefining normal breast cell populations using long noncoding RNAs

por Bitar, Mainá, Rivera, Isela Sarahi, Almeida, Isabela, Shi, Wei, Ferguson, Kaltin, Beesley, Jonathan, Lakhani, Sunil R, Edwards, Stacey L, French, Juliet D
Publicado 2023

A Common Cancer Risk-Associated Allele in the hTERT Locus Encodes a Dominant Negative Inhibitor of Telomerase

por Killedar, Anagha, Stutz, Michael D., Sobinoff, Alexander P., Tomlinson, Christopher G., Bryan, Tracy M., Beesley, Jonathan, Chenevix-Trench, Georgia, Reddel, Roger R., Pickett, Hilda A.
Publicado 2015

Candidate Causal Variants at the 8p12 Breast Cancer Risk Locus Regulate DUSP4

por Glubb, Dylan M., Shi, Wei, Beesley, Jonathan, Fachal, Laura, Pritchard, Jayne-Louise, McCue, Karen, Barnes, Daniel R., Antoniou, Antonis C., Dunning, Alison M., Easton, Douglas F., Chenevix-Trench, Georgia
Publicado 2020

Functional dissection of breast cancer risk-associated TERT promoter variants

por Helbig, Sonja, Wockner, Leesa, Bouendeu, Annick, Hille-Betz, Ursula, McCue, Karen, French, Juliet D, Edwards, Stacey L, Pickett, Hilda A, Reddel, Roger R, Chenevix-Trench, Georgia, Dörk, Thilo, Beesley, Jonathan
Publicado 2017

Paclitaxel sensitivity in relation to ABCB1 expression, efflux and single nucleotide polymorphisms in ovarian cancer

por Gao, Bo, Russell, Amanda, Beesley, Jonathan, Chen, Xiao Qing, Healey, Sue, Henderson, Michelle, Wong, Mark, Emmanuel, Catherine, Galletta, Laura, Johnatty, Sharon E., Bowtell, David, Haber, Michelle, Norris, Murray, Harnett, Paul, Chenevix-Trench, Georgia, Balleine, Rosemary L., deFazio, Anna
Publicado 2014

Functional polymorphisms in the TERT promoter are associated with risk of serious ovarian and breast cancer

por Beesley, Jonathan, Pickett, Hilda, Johnatty, Sharon, Chen, Xiaoqing, Li, Jun Jun, Rider, David, Stutz, Michael, Lambrecht, Diether, Chang-Claude, Jenny, Dork, Thilo, Goodman, Marc, Kiemmney, Bart, Bandera, Elisa, Kelemen, Linda, Wang-Gorke, Shan, Campbell, Ian, Gayther, Simon, Ramus, Susan, Goode, Ellen, Reddel, Roger, Chenevix-Trench, Georgia
Publicado 2012

Identification of a genetic variant associated with treatment outcome in ovarian cancer: the potential role of cholesterol metabolism as a determinant of response to chemotherapy

por Chenevix-Trench, Georgia, Lu, Yi, Johnatty, Sharon, Gamazon, Eric, Beesley, Jonathan, Chen, Xiaoqing, Gao, Bo, Harnett, Paul, Stephanie Huang, R, Despierre, Evelyn, Heitz, Florian, Hogdall, Estrid, Hogdall, Claus, Brown, Robert, Moyisch, Kirsten, Fasching, Peter, Goode, Ellen, Russell, Amanda, Henderson, Michelle, Haber, Michelle, Dolan, Eileen, Macgregor, Stuart, deFazio, Anna
Publicado 2012

Breast cancer risk prediction using a polygenic risk score in the familial setting: a prospective study from the Breast Cancer Family Registry and kConFab

por Li, Hongyan, Feng, Bingjian, Miron, Alexander, Chen, Xiaoqing, Beesley, Jonathan, Bimeh, Emmanuella, Barrowdale, Daniel, John, Esther M., Daly, Mary B., Andrulis, Irene L., Buys, Saundra S., Kraft, Peter, Thorne, Heather, Chenevix-Trench, Georgia, Southey, Melissa, Antoniou, Antonis C., James, Paul A., Terry, Mary Beth, Phillips, Kelly-Anne, Hopper, John L., Mitchell, Gillian, Goldgar, David E.
Publicado 2016

CRISPR screens identify gene targets at breast cancer risk loci

por Tuano, Natasha K., Beesley, Jonathan, Manning, Murray, Shi, Wei, Perlaza-Jimenez, Laura, Malaver-Ortega, Luis F., Paynter, Jacob M., Black, Debra, Civitarese, Andrew, McCue, Karen, Hatzipantelis, Aaron, Hillman, Kristine, Kaufmann, Susanne, Sivakumaran, Haran, Polo, Jose M., Reddel, Roger R., Band, Vimla, French, Juliet D., Edwards, Stacey L., Powell, David R., Chenevix-Trench, Georgia, Rosenbluh, Joseph
Publicado 2023

Genome-wide association study of paclitaxel and carboplatin disposition in women with epithelial ovarian cancer

por Gao, Bo, Lu, Yi, Nieuweboer, Annemieke J. M., Xu, Hongmei, Beesley, Jonathan, Boere, Ingrid, de Graan, Anne-Joy M., de Bruijn, Peter, Gurney, Howard, J. Kennedy, Catherine, Chiew, Yoke-Eng, Johnatty, Sharon E., Beale, Philip, Harrison, Michelle, Luccarini, Craig, Conroy, Don, Mathijssen, Ron H. J., R. Harnett, Paul, Balleine, Rosemary L., Chenevix-Trench, Georgia, Macgregor, Stuart, de Fazio, Anna
Publicado 2018

Chromatin interactome mapping at 139 independent breast cancer risk signals

por Beesley, Jonathan, Sivakumaran, Haran, Moradi Marjaneh, Mahdi, Lima, Luize G., Hillman, Kristine M., Kaufmann, Susanne, Tuano, Natasha, Hussein, Nehal, Ham, Sunyoung, Mukhopadhyay, Pamela, Kazakoff, Stephen, Lee, Jason S., Michailidou, Kyriaki, Barnes, Daniel R., Antoniou, Antonis C., Fachal, Laura, Dunning, Alison M., Easton, Douglas F., Waddell, Nicola, Rosenbluh, Joseph, Möller, Andreas, Chenevix-Trench, Georgia, French, Juliet D., Edwards, Stacey L.
Publicado 2020

Mixed ductal‐lobular carcinomas: evidence for progression from ductal to lobular morphology

por McCart Reed, Amy E, Kutasovic, Jamie R, Nones, Katia, Saunus, Jodi M, Da Silva, Leonard, Newell, Felicity, Kazakoff, Stephen, Melville, Lewis, Jayanthan, Janani, Vargas, Ana Cristina, Reid, Lynne E, Beesley, Jonathan, Chen, Xiao Qing, Patch, Anne-Marie, Clouston, David, Porter, Alan, Evans, Elizabeth, Pearson, John V, Chenevix‐Trench, Georgia, Cummings, Margaret C, Waddell, Nicola, Lakhani, Sunil R, Simpson, Peter T
Publicado 2018

HER3 and downstream pathways are involved in colonization of brain metastases from breast cancer

por Da Silva, Leonard, Simpson, Peter T, Smart, Chanel E, Cocciardi, Sibylle, Waddell, Nic, Lane, Annette, Morrison, Brian J, Vargas, Ana Cristina, Healey, Sue, Beesley, Jonathan, Pakkiri, Pria, Parry, Suzanne, Kurniawan, Nyoman, Reid, Lynne, Keith, Patricia, Faria, Paulo, Pereira, Emilio, Skalova, Alena, Bilous, Michael, Balleine, Rosemary L, Do, Hongdo, Dobrovic, Alexander, Fox, Stephen, Franco, Marcello, Reynolds, Brent, Khanna, Kum Kum, Cummings, Margaret, Chenevix-Trench, Georgia, Lakhani, Sunil R
Publicado 2010

Non-coding RNAs underlie genetic predisposition to breast cancer

por Moradi Marjaneh, Mahdi, Beesley, Jonathan, O’Mara, Tracy A., Mukhopadhyay, Pamela, Koufariotis, Lambros T., Kazakoff, Stephen, Hussein, Nehal, Fachal, Laura, Bartonicek, Nenad, Hillman, Kristine M., Kaufmann, Susanne, Sivakumaran, Haran, Smart, Chanel E., McCart Reed, Amy E., Ferguson, Kaltin, Saunus, Jodi M., Lakhani, Sunil R., Barnes, Daniel R., Antoniou, Antonis C., Dinger, Marcel E., Waddell, Nicola, Easton, Douglas F., Dunning, Alison M., Chenevix-Trench, Georgia, Edwards, Stacey L., French, Juliet D.
Publicado 2020

Immune Cell Associations with Cancer Risk

por Palomero, Luis, Galván-Femenía, Ivan, de Cid, Rafael, Espín, Roderic, Barnes, Daniel R., CIMBA, Blommaert, Eline, Gil-Gil, Miguel, Falo, Catalina, Stradella, Agostina, Ouchi, Dan, Roso-Llorach, Albert, Violan, Concepció, Peña-Chilet, María, Dopazo, Joaquín, Extremera, Ana Isabel, García-Valero, Mar, Herranz, Carmen, Mateo, Francesca, Mereu, Elisabetta, Beesley, Jonathan, Chenevix-Trench, Georgia, Roux, Cecilia, Mak, Tak, Brunet, Joan, Hakem, Razq, Gorrini, Chiara, Antoniou, Antonis C., Lázaro, Conxi, Pujana, Miquel Angel
Publicado 2020

Epigenome erosion and SOX10 drive neural crest phenotypic mimicry in triple-negative breast cancer

por Saunus, Jodi M., De Luca, Xavier M., Northwood, Korinne, Raghavendra, Ashwini, Hasson, Alexander, McCart Reed, Amy E., Lim, Malcolm, Lal, Samir, Vargas, A. Cristina, Kutasovic, Jamie R., Dalley, Andrew J., Miranda, Mariska, Kalaw, Emarene, Kalita-de Croft, Priyakshi, Gresshoff, Irma, Al-Ejeh, Fares, Gee, Julia M. W., Ormandy, Chris, Khanna, Kum Kum, Beesley, Jonathan, Chenevix-Trench, Georgia, Green, Andrew R., Rakha, Emad A., Ellis, Ian O., Nicolau, Dan V., Simpson, Peter T., Lakhani, Sunil R.
Publicado 2022

Estrogen Receptor Beta rs1271572 Polymorphism and Invasive Ovarian Carcinoma Risk: Pooled Analysis within the Ovarian Cancer Association Consortium

por Lurie, Galina, Wilkens, Lynne R., Thompson, Pamela J., Shvetsov, Yurii B., Matsuno, Rayna K., Carney, Michael E., Palmieri, Rachel T., Wu, Anna H., Pike, Malcolm C., Pearce, Celeste L., Menon, Usha, Gentry-Maharaj, Aleksandra, Gayther, Simon A., Ramus, Susan J., Whittemore, Alice S., McGuire, Valerie, Sieh, Weiva, Pharoah, Paul D. P., Song, Honglin, Gronwald, Jacek, Jakubowska, Anna, Cybulski, Cezary, Lubinski, Jan, Schildkraut, Joellen M., Berchuck, Andrew, Krüger Kjær, Susanne, Høgdall, Estrid, Fasching, Peter A., Beckmann, Matthias W., Ekici, Arif B., Hein, Alexander, Chenevix-Trench, Georgia, Webb, Penelope M., Beesley, Jonathan, Goodman, Marc T.
Publicado 2011

Effects of BRCA2 cis-regulation in normal breast and cancer risk amongst BRCA2 mutation carriers

por Maia, Ana-Teresa, Antoniou, Antonis C, O'Reilly, Martin, Samarajiwa, Shamith, Dunning, Mark, Kartsonaki, Christiana, Chin, Suet-Feung, Curtis, Christina N, McGuffog, Lesley, Domchek, Susan M, Easton, Douglas F, Peock, Susan, Frost, Debra, Evans, D Gareth, Eeles, Ros, Izatt, Louise, Adlard, Julian, Eccles, Diana, Sinilnikova, Olga M, Mazoyer, Sylvie, Stoppa-Lyonnet, Dominique, Gauthier-Villars, Marion, Faivre, Laurence, Venat-Bouvet, Laurence, Delnatte, Capucine, Nevanlinna, Heli, Couch, Fergus J, Godwin, Andrew K, Caligo, Maria Adelaide, Barkardottir, Rosa B, Chen, Xiaoqing, Beesley, Jonathan, Healey, Sue, Caldas, Carlos, Chenevix-Trench, Georgia, Ponder, Bruce AJ
Publicado 2012