Substrate binding and specificity of rhomboid intramembrane protease revealed by substrate–peptide complex structures

por Zoll, Sebastian, Stanchev, Stancho, Began, Jakub, Škerle, Jan, Lepšík, Martin, Peclinovská, Lucie, Majer, Pavel, Strisovsky, Kvido
Publicado 2014

The role of invariant surface glycoprotein 75 in xenobiotic acquisition by African trypanosomes

por Makarov, Alexandr, Began, Jakub, Mautone, Ileana Corvo, Pinto, Erika, Ferguson, Liam, Zoltner, Martin, Zoll, Sebastian, Field, Mark C.
Publicado 2023

The History of Anti-Trypanosome Vaccine Development Shows That Highly Immunogenic and Exposed Pathogen-Derived Antigens Are Not Necessarily Good Target Candidates: Enolase and ISG7...

por Magez, Stefan, Li, Zeng, Nguyen, Hang Thi Thu, Pinto Torres, Joar Esteban, Van Wielendaele, Pieter, Radwanska, Magdalena, Began, Jakub, Zoll, Sebastian, Sterckx, Yann G.-J.
Publicado 2021

Cryo-EM structures of Trypanosoma brucei gambiense ISG65 with human complement C3 and C3b and their roles in alternative pathway restriction

por Sülzen, Hagen, Began, Jakub, Dhillon, Arun, Kereïche, Sami, Pompach, Petr, Votrubova, Jitka, Zahedifard, Farnaz, Šubrtova, Adriana, Šafner, Marie, Hubalek, Martin, Thompson, Maaike, Zoltner, Martin, Zoll, Sebastian
Publicado 2023

Rhomboid intramembrane protease YqgP licenses bacterial membrane protein quality control as adaptor of FtsH AAA protease

por Began, Jakub, Cordier, Baptiste, Březinová, Jana, Delisle, Jordan, Hexnerová, Rozálie, Srb, Pavel, Rampírová, Petra, Kožíšek, Milan, Baudet, Mathieu, Couté, Yohann, Galinier, Anne, Veverka, Václav, Doan, Thierry, Strisovsky, Kvido
Publicado 2020

General and Modular Strategy for Designing Potent, Selective, and Pharmacologically Compliant Inhibitors of Rhomboid Proteases

por Tichá, Anežka, Stanchev, Stancho, Vinothkumar, Kutti R., Mikles, David C., Pachl, Petr, Began, Jakub, Škerle, Jan, Švehlová, Kateřina, Nguyen, Minh T.N., Verhelst, Steven H.L., Johnson, Darren C., Bachovchin, Daniel A., Lepšík, Martin, Majer, Pavel, Strisovsky, Kvido
Publicado 2017