Biosynthetic Versatility and Coordinated Action of 5′-Deoxyadenosyl Radicals in Deazaflavin Biosynthesis

por Philmus, Benjamin, Decamps, Laure, Berteau, Olivier, Begley, Tadhg P.
Publicado 2015

Biosynthesis of a Thiamin Antivitamin in Clostridium botulinum

por Cooper, Lisa E., O’Leary, Seán E., Begley, Tadhg P.
Publicado 2014

Radiosynthesis of 5-[(18)F]Fluoro-1,2,3-triazoles through Aqueous Iodine–[(18)F]Fluorine Exchange Reaction

por Zhang, Xiang, Basuli, Falguni, Abdelwahed, Sameh, Begley, Tadhg, Swenson, Rolf
Publicado 2021

Crystal Structure of a Sulfur Carrier Protein Complex Found in the Cysteine Biosynthetic Pathway of Mycobacterium tuberculosis

por Jurgenson, Christopher T., Burns, Kristin E., Begley, Tadhg P., Ealick, Steven E.
Publicado 2008

Molybdopterin Biosynthesis: Trapping of Intermediates for the MoaA-Catalyzed Reaction Using 2′-DeoxyGTP and 2′-ChloroGTP as Substrate Analogues.

por Mehta, Angad P., Abdelwahed, Sameh H., Xu, Hui, Begley, Tadhg P.
Publicado 2014

RNA-seq Analysis Reveals That an ECF σ Factor, AcsS, Regulates Achromobactin Biosynthesis in Pseudomonas syringae pv. syringae B728a

por Greenwald, Jessica W., Greenwald, Charles J., Philmus, Benjamin J., Begley, Tadhg P., Gross, Dennis C.
Publicado 2012

Non-canonical active site architecture of the radical SAM thiamin pyrimidine synthase

por Fenwick, Michael K., Mehta, Angad P., Zhang, Yang, Abdelwahed, Sameh H., Begley, Tadhg P., Ealick, Steven E.
Publicado 2015

The Vitamin B1 Metabolism of Staphylococcus aureus Is Controlled at Enzymatic and Transcriptional Levels

por Müller, Ingrid B., Bergmann, Bärbel, Groves, Matthew R., Couto, Isabel, Amaral, Leonard, Begley, Tadhg P., Walter, Rolf D., Wrenger, Carsten
Publicado 2009

Trapping and structural characterisation of a covalent intermediate in vitamin B(6) biosynthesis catalysed by the Pdx1 PLP synthase

por Rodrigues, Matthew J., Giri, Nitai, Royant, Antoine, Zhang, Yang, Bolton, Rachel, Evans, Gwyndaf, Ealick, Steve E., Begley, Tadhg, Tews, Ivo
Publicado 2021

Trapping and Electron Paramagnetic Resonance Characterization of the 5′dAdo(•) Radical in a Radical S-Adenosyl Methionine Enzyme Reaction with a Non-Native Substrate

por Sayler, Richard I., Stich, Troy A., Joshi, Sumedh, Cooper, Nicole, Shaw, Jared T., Begley, Tadhg P., Tantillo, Dean J., Britt, R. David
Publicado 2019

Saccharomyces cerevisiae THI4p is a suicidal thiamin thiazole synthase

por Chatterjee, Abhishek, Abeydeera, N. Dinuka, Bale, Shridhar, Pai, Pei-Jing, Dorrestein, Pieter C., Russell, David H., Ealick, Steven E., Begley, Tadhg P.
Publicado 2011

Globally Important Haptophyte Algae Use Exogenous Pyrimidine Compounds More Efficiently than Thiamin

por Gutowska, Magdalena A., Shome, Brateen, Sudek, Sebastian, McRose, Darcy L., Hamilton, Maria, Giovannoni, Stephen J., Begley, Tadhg P., Worden, Alexandra Z.
Publicado 2017

Alternatives to vitamin B(1) uptake revealed with discovery of riboswitches in multiple marine eukaryotic lineages

por McRose, Darcy, Guo, Jian, Monier, Adam, Sudek, Sebastian, Wilken, Susanne, Yan, Shuangchun, Mock, Thomas, Archibald, John M, Begley, Tadhg P, Reyes-Prieto, Adrian, Worden, Alexandra Z
Publicado 2014

The Subsystems Approach to Genome Annotation and its Use in the Project to Annotate 1000 Genomes

por Overbeek, Ross, Begley, Tadhg, Butler, Ralph M., Choudhuri, Jomuna V., Chuang, Han-Yu, Cohoon, Matthew, de Crécy-Lagard, Valérie, Diaz, Naryttza, Disz, Terry, Edwards, Robert, Fonstein, Michael, Frank, Ed D., Gerdes, Svetlana, Glass, Elizabeth M., Goesmann, Alexander, Hanson, Andrew, Iwata-Reuyl, Dirk, Jensen, Roy, Jamshidi, Neema, Krause, Lutz, Kubal, Michael, Larsen, Niels, Linke, Burkhard, McHardy, Alice C., Meyer, Folker, Neuweger, Heiko, Olsen, Gary, Olson, Robert, Osterman, Andrei, Portnoy, Vasiliy, Pusch, Gordon D., Rodionov, Dmitry A., Rückert, Christian, Steiner, Jason, Stevens, Rick, Thiele, Ines, Vassieva, Olga, Ye, Yuzhen, Zagnitko, Olga, Vonstein, Veronika
Publicado 2005