miR-21 expression and clinical outcome in locally advanced pancreatic cancer: exploratory analysis of the pancreatic cancer Erbitux, radiotherapy and UFT (PERU) trial

por Khan, Khurum, Cunningham, David, Peckitt, Clare, Barton, Sarah, Tait, Diana, Hawkins, Maria, Watkins, David, Starling, Naureen, Rao, Sheela, Begum, Ruwaida, Thomas, Janet, Oates, Jacqui, Guzzardo, Vincenza, Fassan, Matteo, Braconi, Chiara, Chau, Ian
Publicado 2016

Comparison between MRI and pathology in the assessment of tumour regression grade in rectal cancer

por Sclafani, Francesco, Brown, Gina, Cunningham, David, Wotherspoon, Andrew, Mendes, Larissa Sena Teixeira, Balyasnikova, Svetlana, Evans, Jessica, Peckitt, Clare, Begum, Ruwaida, Tait, Diana, Tabernero, Josep, Glimelius, Bengt, Roselló, Susana, Thomas, Janet, Oates, Jacqui, Chau, Ian
Publicado 2017

Rationale and design of the POLEM trial: avelumab plus fluoropyrimidine-based chemotherapy as adjuvant treatment for stage III mismatch repair deficient or POLE exonuclease domain...

por Lau, David, Kalaitzaki, Eleftheria, Church, David N, Pandha, Hardev, Tomlinson, Ian, Annels, Nicola, Gerlinger, Marco, Sclafani, Francesco, Smith, Gillian, Begum, Ruwaida, Crux, Richard, Gillbanks, Angela, Wordsworth, Sarah, Chau, Ian, Starling, Naureen, Cunningham, David, Dhillon, Tony
Publicado 2020

Detecting and Tracking Circulating Tumour DNA Copy Number Profiles during First Line Chemotherapy in Oesophagogastric Adenocarcinoma

por Davidson, Michael, Barber, Louise J., Woolston, Andrew, Cafferkey, Catherine, Mansukhani, Sonia, Griffiths, Beatrice, Moorcraft, Sing-Yu, Rana, Isma, Begum, Ruwaida, Assiotis, Ioannis, Matthews, Nik, Rao, Sheela, Watkins, David, Chau, Ian, Cunningham, David, Starling, Naureen, Gerlinger, Marco
Publicado 2019

ctDNA guided adjuvant chemotherapy versus standard of care adjuvant chemotherapy after curative surgery in patients with high risk stage II or stage III colorectal cancer: a multi-...

por Slater, Susanna, Bryant, Annette, Chen, Hsiang-Chi, Begum, Ruwaida, Rana, Isma, Aresu, Maria, Peckitt, Clare, Zhitkov, Oleg, Lazaro-Alcausi, Retchel, Borja, Victoria, Powell, Rachel, Lowery, David, Hubank, Michael, Rich, Thereasa, Anandappa, Gayathri, Chau, Ian, Starling, Naureen, Cunningham, David
Publicado 2023

Ibrutinib in c-MYC and HER2 Amplified Oesophagogastric Carcinoma: Results of the Proof-of-Concept iMYC Study

por Turkes, Fiona, Bryant, Annette, Begum, Ruwaida, Davidson, Michael, Kalaitzaki, Eleftheria, Aresu, Maria, Lazaro-Alcausi, Retchel, Bryant, Jane, Rana, Isma, Chua, Sue, Aronson, Lauren, Hulkki-Wilson, Sanna, Fribbens, Charlotte, Watkins, David, Rao, Sheela, Starling, Naureen, Cunningham, David, Chong, Irene Y., Chau, Ian
Publicado 2022

Genomic loss of heterozygosity and survival in the REAL3 trial

por Smyth, Elizabeth C., Cafferkey, Catherine, Loehr, Andrea, Waddell, Tom, Begum, Ruwaida, Peckitt, Clare, Harding, Thomas C., Nguyen, Minh, Okines, Alicia F., Raponi, Mitch, Rao, Sheela, Watkins, David, Starling, Naureen, Middleton, Gary W., Wadsley, Jonathan, Mansoor, Wasat, Crosby, Tom, Wotherspoon, Andrew, Chau, Ian, Cunningham, David
Publicado 2018

Analytical Validation of Multiplex Biomarker Assay to Stratify Colorectal Cancer into Molecular Subtypes

por Ragulan, Chanthirika, Eason, Katherine, Fontana, Elisa, Nyamundanda, Gift, Tarazona, Noelia, Patil, Yatish, Poudel, Pawan, Lawlor, Rita T., Del Rio, Maguy, Koo, Si-Lin, Tan, Wah-Siew, Sclafani, Francesco, Begum, Ruwaida, Teixeira Mendes, Larissa S., Martineau, Pierre, Scarpa, Aldo, Cervantes, Andrés, Tan, Iain Beehuat, Cunningham, David, Sadanandam, Anguraj
Publicado 2019

The Mutational Concordance of Fixed Formalin Paraffin Embedded and Fresh Frozen Gastro-Oesophageal Tumours Using Whole Exome Sequencing

por Chong, Irene Y., Starling, Naureen, Rust, Alistair, Alexander, John, Aronson, Lauren, Llorca-Cardenosa, Marta, Chauhan, Ritika, Chaudry, Asif, Kumar, Sacheen, Fenwick, Kerry, Assiotis, Ioannis, Matthews, Nik, Begum, Ruwaida, Wotherspoon, Andrew, Terlizzo, Monica, Watkins, David, Chau, Ian, Lord, Christopher J., Haider, Syed, Rao, Sheela, Cunningham, David
Publicado 2021

Sequence variation in mature microRNA-608 and benefit from neo-adjuvant treatment in locally advanced rectal cancer patients

por Sclafani, Francesco, Chau, Ian, Cunningham, David, Lampis, Andrea, Hahne, Jens Claus, Ghidini, Michele, Lote, Hazel, Zito, Domenico, Tabernero, Josep, Glimelius, Bengt, Cervantes, Andres, Begum, Ruwaida, De Castro, David Gonzalez, Wilson, Sanna Hulkki, Peckitt, Clare, Eltahir, Zakaria, Wotherspoon, Andrew, Tait, Diana, Brown, Gina, Oates, Jacqueline, Braconi, Chiara, Valeri, Nicola
Publicado 2016

KRAS and BRAF mutations in circulating tumour DNA from locally advanced rectal cancer

por Sclafani, Francesco, Chau, Ian, Cunningham, David, Hahne, Jens C., Vlachogiannis, George, Eltahir, Zakaria, Lampis, Andrea, Braconi, Chiara, Kalaitzaki, Eleftheria, De Castro, David Gonzalez, Wotherspoon, Andrew, Capdevila, Jaume, Glimelius, Bengt, Tarazona, Noelia, Begum, Ruwaida, Lote, Hazel, Hulkki Wilson, Sanna, Mentrasti, Giulia, Brown, Gina, Tait, Diana, Oates, Jacqueline, Valeri, Nicola
Publicado 2018

Diagnostic Accuracy and Safety of Coaxial System in Oncology Patients Treated in a Specialist Cancer Center With Prospective Validation Within Clinical Trial Data

por Khan, Khurum, Gonzalez-Exposito, Reyes, Cunningham, David, Koh, Dow-Mu, Woolston, Andrew, Barber, Louise, Griffiths, Beatrice, Kouvelakis, Kyriakos, Calamai, Vanessa, Bali, Monia, Khan, Nasir, Bryant, Annette, Saffery, Claire, Dearman, Charles, Begum, Ruwaida, Rao, Sheela, Starling, Naureen, Watkins, David, Chau, Ian, Braconi, Chiara, Valeri, Nicola, Gerlinger, Marco, Fotiadis, Nicos
Publicado 2020

Molecular profiling of colorectal pulmonary metastases and primary tumours: implications for targeted treatment

por Moorcraft, Sing Y., Jones, Thomas, Walker, Brian A., Ladas, George, Kalaitzaki, Eleftheria, Yuan, Lina, Begum, Ruwaida, Eltahir, Zakaria, Wotherspoon, Andrew, Montero-Fernandez, Angeles, Teixeira Mendes, Larissa S., Gonzalez de Castro, David, Wilson, Sanna Hulkki, Proszek, Paula, To, Ye M., Hawkes, Eliza, Roy, Amitesh, Cunningham, David, Rao, Sheela, Watkins, David, Starling, Naureen, Bowcock, Anne M., Chau, Ian
Publicado 2017

SARS-CoV-2 Vaccine Immunogenicity in Patients with Gastrointestinal Cancer Receiving Systemic Anti-Cancer Therapy

por Lau, David K, Aresu, Maria, Planche, Timothy, Tran, Amina, Lazaro-Alcausi, Retchel, Duncan, Julie, Kidd, Shannon, Cromarty, Susan, Begum, Ruwaida, Rana, Isma, Li, Su, Suwaidan, Ali Abdulnabi, Monahan, Irene, Clark, David J, Eckersley, Nicholas, Staines, Henry M, Groppelli, Elisabetta, Krishna, Sanjeev, Mayora-Neto, Martin, Temperton, Nigel, Fribbens, Charlotte, Watkins, David, Starling, Naureen, Chau, Ian, Cunningham, David, Rao, Sheela
Publicado 2022

CHOP versus GEM-P in previously untreated patients with peripheral T-cell lymphoma (CHEMO-T): a phase 2, multicentre, randomised, open-label trial

por Gleeson, Mary, Peckitt, Clare, To, Ye Mong, Edwards, Laurice, Oates, Jacqueline, Wotherspoon, Andrew, Attygalle, Ayoma D, Zerizer, Imene, Sharma, Bhupinder, Chua, Sue, Begum, Ruwaida, Chau, Ian, Johnson, Peter, Ardeshna, Kirit M, Hawkes, Eliza A, Macheta, Marian P, Collins, Graham P, Radford, John, Forbes, Adam, Hart, Alistair, Montoto, Silvia, McKay, Pamela, Benstead, Kim, Morley, Nicholas, Kalakonda, Nagesh, Hasan, Yasmin, Turner, Deborah, Cunningham, David
Publicado 2018

Intratumoral Transcriptome Heterogeneity Is Associated With Patient Prognosis and Sidedness in Patients With Colorectal Cancer Treated With Anti-EGFR Therapy From the CO.20 Trial

por Fontana, Elisa, Nyamundanda, Gift, Cunningham, David, Tu, Dongsheng, Cheang, Maggie C.U., Jonker, Derek J., Siu, Lillian L., Sclafani, Francesco, Eason, Katherine, Ragulan, Chanthirika, Bali, Maria Antonietta, Hulkki-Wilson, Sanna, Loree, Jonathan M., Waring, Paul M., Giordano, Mirella, Lawrence, Patrick, Rodrigues, Daniel Nava, Begum, Ruwaida, Shapiro, Jeremy D., Price, Timothy J., Cremolini, Chiara, Starling, Naureen, Pietrantonio, Filippo, Trusolino, Livio, O’Callaghan, Christopher J., Sadanandam, Anguraj
Publicado 2020

Functional imaging and circulating biomarkers of response to regorafenib in treatment-refractory metastatic colorectal cancer patients in a prospective phase II study

por Khan, Khurum, Rata, Mihaela, Cunningham, David, Koh, Dow-Mu, Tunariu, Nina, Hahne, Jens C, Vlachogiannis, George, Hedayat, Somaieh, Marchetti, Silvia, Lampis, Andrea, Damavandi, Mahnaz Darvish, Lote, Hazel, Rana, Isma, Williams, Anja, Eccles, Suzanne A, Fontana, Elisa, Collins, David, Eltahir, Zakaria, Rao, Sheela, Watkins, David, Starling, Naureen, Thomas, Jan, Kalaitzaki, Eleftheria, Fotiadis, Nicos, Begum, Ruwaida, Bali, Maria, Rugge, Massimo, Temple, Eleanor, Fassan, Matteo, Chau, Ian, Braconi, Chiara, Valeri, Nicola
Publicado 2018

EGFR amplification and outcome in a randomised phase III trial of chemotherapy alone or chemotherapy plus panitumumab for advanced gastro-oesophageal cancers

por Smyth, Elizabeth C, Vlachogiannis, Georgios, Hedayat, Somaieh, Harbery, Alice, Hulkki-Wilson, Sanna, Salati, Massimiliano, Kouvelakis, Kyriakos, Fernandez-Mateos, Javier, Cresswell, George D, Fontana, Elisa, Seidlitz, Therese, Peckitt, Clare, Hahne, Jens C, Lampis, Andrea, Begum, Ruwaida, Watkins, David, Rao, Sheela, Starling, Naureen, Waddell, Tom, Okines, Alicia, Crosby, Tom, Mansoor, Was, Wadsley, Jonathan, Middleton, Gary, Fassan, Matteo, Wotherspoon, Andrew, Braconi, Chiara, Chau, Ian, Vivanco, Igor, Sottoriva, Andrea, Stange, Daniel E, Cunningham, David, Valeri, Nicola
Publicado 2021

MIR21 Drives Resistance to Heat Shock Protein 90 Inhibition in Cholangiocarcinoma

por Lampis, Andrea, Carotenuto, Pietro, Vlachogiannis, Georgios, Cascione, Luciano, Hedayat, Somaieh, Burke, Rosemary, Clarke, Paul, Bosma, Else, Simbolo, Michele, Scarpa, Aldo, Yu, Sijia, Cole, Rebecca, Smyth, Elizabeth, Mateos, Javier Fernández, Begum, Ruwaida, Hezelova, Blanka, Eltahir, Zakaria, Wotherspoon, Andrew, Fotiadis, Nicos, Bali, Maria Antonietta, Nepal, Chirag, Khan, Khurum, Stubbs, Mark, Hahne, Jens C., Gasparini, Pierluigi, Guzzardo, Vincenza, Croce, Carlo M., Eccles, Suzanne, Fassan, Matteo, Cunningham, David, Andersen, Jesper B., Workman, Paul, Valeri, Nicola, Braconi, Chiara
Publicado 2018

Modulation of Biliary Cancer Chemo‐Resistance Through MicroRNA‐Mediated Rewiring of the Expansion of CD133+ Cells

por Carotenuto, Pietro, Hedayat, Somaieh, Fassan, Matteo, Cardinale, Vincenzo, Lampis, Andrea, Guzzardo, Vincenza, Vicentini, Caterina, Scarpa, Aldo, Cascione, Luciano, Costantini, Daniele, Carpino, Guido, Alvaro, Domenico, Ghidini, Michele, Trevisani, Francesco, Te Poele, Robert, Salati, Massimiliano, Ventura, Sofia, Vlachogiannis, Georgios, Hahne, Jens C., Boulter, Luke, Forbes, Stuart J., Guest, Rachel V., Cillo, Umberto, Said‐Huntingford, Ian, Begum, Ruwaida, Smyth, Elizabeth, Michalarea, Vasiliki, Cunningham, David, Rimassa, Lorenza, Santoro, Armando, Roncalli, Massimo, Kirkin, Vladimir, Clarke, Paul, Workman, Paul, Valeri, Nicola, Braconi, Chiara
Publicado 2020