CRISPR-Cas Systems and the Paradox of Self-Targeting Spacers

por Wimmer, Franziska, Beisel, Chase L.
Publicado 2020

CRISPR technologies and the search for the PAM-free nuclease

por Collias, Daphne, Beisel, Chase L.
Publicado 2021

CRISPR memories in single cells

por Sparmann, Anke, Beisel, Chase L
Publicado 2022

Design Principles for Riboswitch Function

por Beisel, Chase L., Smolke, Christina D.
Publicado 2009

Rapid Testing of CRISPR Nucleases and Guide RNAs in an E. coli Cell-Free Transcription-Translation System

por Marshall, Ryan, Beisel, Chase L., Noireaux, Vincent
Publicado 2020

A CRISPR design for next-generation antimicrobials

por Beisel, Chase L, Gomaa, Ahmed A, Barrangou, Rodolphe
Publicado 2014

Impact of Residual Inducer on Titratable Expression Systems

por Afroz, Taliman, Luo, Michelle L., Beisel, Chase L.
Publicado 2015

Shortened CRISPR-Cas9 arrays enable multiplexed gene targeting in bacteria from a smaller DNA footprint

por Gawlitt, Sandra, Liao, Chunyu, Achmedov, Tatjana, Beisel, Chase L.
Publicado 2023

Repurposing endogenous type I CRISPR-Cas systems for programmable gene repression

por Luo, Michelle L., Mullis, Adam S., Leenay, Ryan T., Beisel, Chase L.
Publicado 2015

Sequence-independent RNA sensing and DNA targeting by a split domain CRISPR–Cas12a gRNA switch

por Collins, Scott P, Rostain, William, Liao, Chunyu, Beisel, Chase L
Publicado 2021

Model-guided design of ligand-regulated RNAi for programmable control of gene expression

por Beisel, Chase L, Bayer, Travis S, Hoff, Kevin G, Smolke, Christina D
Publicado 2008

Trade-offs in Engineering Sugar Utilization Pathways for Titratable Control

por Afroz, Taliman, Biliouris, Konstantinos, Boykin, Kelsey E., Kaznessis, Yiannis, Beisel, Chase L.
Publicado 2014

An educational module to explore CRISPR technologies with a cell-free transcription-translation system

por Collias, Daphne, Marshall, Ryan, Collins, Scott P, Beisel, Chase L, Noireaux, Vincent
Publicado 2019

Synthetic control of a fitness tradeoff in yeast nitrogen metabolism

por Bayer, Travis S, Hoff, Kevin G, Beisel, Chase L, Lee, Jack J, Smolke, Christina D
Publicado 2009

Characterization of Cas12a nucleases reveals diverse PAM profiles between closely-related orthologs

por Jacobsen, Thomas, Ttofali, Fani, Liao, Chunyu, Manchalu, Srinivas, Gray, Benjamin N, Beisel, Chase L
Publicado 2020

Design of small molecule-responsive microRNAs based on structural requirements for Drosha processing

por Beisel, Chase L., Chen, Yvonne Y., Culler, Stephanie J., Hoff, Kevin G., Smolke, Christina D.
Publicado 2011

Tunable self-cleaving ribozymes for modulating gene expression in eukaryotic systems

por Jacobsen, Thomas, Yi, Gloria, Al Asafen, Hadel, Jermusyk, Ashley A., Beisel, Chase L., Reeves, Gregory T.
Publicado 2020

Programmable Removal of Bacterial Strains by Use of Genome-Targeting CRISPR-Cas Systems

por Gomaa, Ahmed A., Klumpe, Heidi E., Luo, Michelle L., Selle, Kurt, Barrangou, Rodolphe, Beisel, Chase L.
Publicado 2014

RNA targeting unleashes indiscriminate nuclease activity of CRISPR–Cas12a2

por Bravo, Jack P. K., Hallmark, Thomson, Naegle, Bronson, Beisel, Chase L., Jackson, Ryan N., Taylor, David W.
Publicado 2023

Bacterial Adaptation to the Host's Diet Is a Key Evolutionary Force Shaping Drosophila-Lactobacillus Symbiosis

por Martino, Maria Elena, Joncour, Pauline, Leenay, Ryan, Gervais, Hugo, Shah, Malay, Hughes, Sandrine, Gillet, Benjamin, Beisel, Chase, Leulier, François
Publicado 2018