Step by step: towards a better understanding of the genetic architecture of Alzheimer’s disease

por Lambert, Jean-Charles, Ramirez, Alfredo, Grenier-Boley, Benjamin, Bellenguez, Céline
Publicado 2023

A robust clustering algorithm for identifying problematic samples in genome-wide association studies

por Bellenguez, Céline, Strange, Amy, Freeman, Colin, Donnelly, Peter, Spencer, Chris C.A.
Publicado 2012

Accuracy of heritability estimations in presence of hidden population stratification

por Dandine-Roulland, Claire, Bellenguez, Céline, Debette, Stéphanie, Amouyel, Philippe, Génin, Emmanuelle, Perdry, Hervé
Publicado 2016

Genetics of PlGF plasma levels highlights a role of its receptors and supports the link between angiogenesis and immunity

por Ruggiero, Daniela, Nutile, Teresa, Nappo, Stefania, Tirozzi, Alfonsina, Bellenguez, Celine, Leutenegger, Anne-Louise, Ciullo, Marina
Publicado 2021

Genetic Variants Modulating CRIPTO Serum Levels Identified by Genome-Wide Association Study in Cilento Isolates

por Ruggiero, Daniela, Nappo, Stefania, Nutile, Teresa, Sorice, Rossella, Talotta, Francesco, Giorgio, Emilia, Bellenguez, Celine, Leutenegger, Anne-Louise, Liguori, Giovanna L., Ciullo, Marina
Publicado 2015

Comparative assessment of methods for estimating individual genome-wide homozygosity-by-descent from human genomic data

por Polašek, Ozren, Hayward, Caroline, Bellenguez, Celine, Vitart, Veronique, Kolčić, Ivana, McQuillan, Ruth, Saftić, Vanja, Gyllensten, Ulf, Wilson, James F, Rudan, Igor, Wright, Alan F, Campbell, Harry, Leutenegger, Anne-Louise
Publicado 2010

Six Novel Loci Associated with Circulating VEGF Levels Identified by a Meta-analysis of Genome-Wide Association Studies

por Choi, Seung Hoan, Ruggiero, Daniela, Sorice, Rossella, Song, Ci, Nutile, Teresa, Vernon Smith, Albert, Concas, Maria Pina, Traglia, Michela, Barbieri, Caterina, Ndiaye, Ndeye Coumba, Stathopoulou, Maria G., Lagou, Vasiliki, Maestrale, Giovanni Battista, Sala, Cinzia, Debette, Stephanie, Kovacs, Peter, Lind, Lars, Lamont, John, Fitzgerald, Peter, Tönjes, Anke, Gudnason, Vilmundur, Toniolo, Daniela, Pirastu, Mario, Bellenguez, Celine, Vasan, Ramachandran S., Ingelsson, Erik, Leutenegger, Anne-Louise, Johnson, Andrew D., DeStefano, Anita L., Visvikis-Siest, Sophie, Seshadri, Sudha, Ciullo, Marina
Publicado 2016

Association of variants in HTRA1 and NOTCH3 with MRI-defined extremes of cerebral small vessel disease in older subjects

por Mishra, Aniket, Chauhan, Ganesh, Violleau, Marie-Helene, Vojinovic, Dina, Jian, Xueqiu, Bis, Joshua C, Li, Shuo, Saba, Yasaman, Grenier-Boley, Benjamin, Yang, Qiong, Bartz, Traci M, Hofer, Edith, Soumaré, Aïcha, Peng, Fen, Duperron, Marie-Gabrielle, Foglio, Mario, Mosley, Thomas H, Schmidt, Reinhold, Psaty, Bruce M, Launer, Lenore J, Boerwinkle, Eric, Zhu, Yicheng, Mazoyer, Bernard, Lathrop, Mark, Bellenguez, Celine, Van Duijn, Cornelia M, Ikram, M Arfan, Schmidt, Helena, Longstreth, W T, Fornage, Myriam, Seshadri, Sudha, Joutel, Anne, Tzourio, Christophe, Debette, Stephanie
Publicado 2019

Multiomics integrative analysis identifies APOE allele-specific blood biomarkers associated to Alzheimer’s disease etiopathogenesis

por Madrid, Laura, Moreno-Grau, Sonia, Ahmad, Shahzad, González-Pérez, Antonio, de Rojas, Itziar, Xia, Rui, Martino Adami, Pamela V., García-González, Pablo, Kleineidam, Luca, Yang, Qiong, Damotte, Vincent, Bis, Joshua C., Noguera-Perea, Fuensanta, Bellenguez, Céline, Jian, Xueqiu, Marín-Muñoz, Juan, Grenier-Boley, Benjamin, Orellana, Adela, Ikram, M. Arfan, Amouyel, Philippe, Satizabal, Claudia L., Real, Luis Miguel, Antúnez-Almagro, Carmen, DeStefano, Anita, Cabrera-Socorro, Alfredo, Sims, Rebecca, Van Duijn, Cornelia M., Boerwinkle, Eric, Ramírez, Alfredo, Fornage, Myriam, Lambert, Jean-Charles, Williams, Julie, Seshadri, Sudha, Ried, Janina S., Ruiz, Agustín, Saez, Maria Eugenia
Publicado 2021

Missense variant in TREML2 protects against Alzheimer's disease

por Benitez, Bruno A., Jin, Sheng Chih, Guerreiro, Rita, Graham, Rob, Lord, Jenny, Harold, Denise, Sims, Rebecca, Lambert, Jean-Charles, Gibbs, J. Raphael, Bras, Jose, Sassi, Celeste, Harari, Oscar, Bertelsen, Sarah, Lupton, Michelle K., Powell, John, Bellenguez, Celine, Brown, Kristelle, Medway, Christopher, Haddick, Patrick CG., van der Brug, Marcel P., Bhangale, Tushar, Ortmann, Ward, Behrens, Tim, Mayeux, Richard, Pericak-Vance, Margaret A., Farrer, Lindsay A., Schellenberg, Gerard D., Haines, Jonathan L., Turton, Jim, Braae, Anne, Barber, Imelda, Fagan, Anne M., Holtzman, David M., Morris, John C., Williams, Julie, Kauwe, John S.K., Amouyel, Philippe, Morgan, Kevin, Singleton, Andy, Hardy, John, Goate, Alison M., Cruchaga, Carlos
Publicado 2014

Dissection of the genetics of Parkinson's disease identifies an additional association 5′ of SNCA and multiple associated haplotypes at 17q21

por Spencer, Chris C.A., Plagnol, Vincent, Strange, Amy, Gardner, Michelle, Paisan-Ruiz, Coro, Band, Gavin, Barker, Roger A., Bellenguez, Celine, Bhatia, Kailash, Blackburn, Hannah, Blackwell, Jennie M., Bramon, Elvira, Brown, Martin A., Brown, Matthew A., Burn, David, Casas, Juan-Pablo, Chinnery, Patrick F., Clarke, Carl E., Corvin, Aiden, Craddock, Nicholas, Deloukas, Panos, Edkins, Sarah, Evans, Jonathan, Freeman, Colin, Gray, Emma, Hardy, John, Hudson, Gavin, Hunt, Sarah, Jankowski, Janusz, Langford, Cordelia, Lees, Andrew J., Markus, Hugh S., Mathew, Christopher G., McCarthy, Mark I., Morrison, Karen E., Palmer, Colin N.A., Pearson, Justin P., Peltonen, Leena, Pirinen, Matti, Plomin, Robert, Potter, Simon, Rautanen, Anna, Sawcer, Stephen J., Su, Zhan, Trembath, Richard C., Viswanathan, Ananth C., Williams, Nigel W., Morris, Huw R., Donnelly, Peter, Wood, Nicholas W.
Publicado 2011

Common variants near ATM are associated with glycemic response to metformin in type 2 diabetes

por Zhou, Kaixin, Bellenguez, Celine, Spencer, Chris CA, Bennett, Amanda J, Coleman, Ruth L, Tavendale, Roger, Hawley, Simon A., Donnelly, Louise A, Schofield, Chris, Groves, Christopher J, Burch, Lindsay, Carr, Fiona, Strange, Amy, Freeman, Colin, Blackwell, Jenefer M, Bramon, Elvira, Brown, Matthew A, Casas, Juan P, Corvin, Aiden, Craddock, Nicholas, Deloukas, Panos, Dronov, Serge, Duncanson, Audrey, Edkins, Sarah, Gray, Emma, Hunt, Sarah, Jankowski, Janusz, Langford, Cordelia, Markus, Hugh S, Mathew, Christopher G, Plomin, Robert, Rautanen, Anna, Sawcer, Stephen J, Samani, Nilesh J, Trembath, Richard, Viswanathan, Ananth C, Wood, Nicholas W, Harries, Lorna W, Hattersley, Andrew T, Doney, Alex SF, Colhoun, Helen, Morris, Andrew D, Sutherland, Calum, Hardie, D. Grahame, Peltonen, Leena, McCarthy, Mark I, Holman, Rury R., Palmer, Colin N.A., Donnelly, Peter, Pearson, Ewan R
Publicado 2010

Common variants in the HLA-DRB1-HLA-DQA1 Class II region are associated with susceptibility to visceral leishmaniasis

por Fakiola, Michaela, Strange, Amy, Cordell, Heather J., Miller, E. Nancy, Pirinen, Matti, Su, Zhan, Mishra, Anshuman, Mehrotra, Sanjana, Monteiro, Gloria R., Band, Gavin, Bellenguez, Céline, Dronov, Serge, Edkins, Sarah, Freeman, Colin, Giannoulatou, Eleni, Gray, Emma, Hunt, Sarah E., Lacerda, Henio G., Langford, Cordelia, Pearson, Richard, Pontes, Núbia N., Rai, Madhukar, Singh, S.P., Smith, Linda, Sousa, Olivia, Vukcevic, Damjan, Bramon, Elvira, Brown, Matthew A., Casas, Juan P., Corvin, Aiden, Duncanson, Audrey, Jankowski, Janusz, Markus, Hugh S., Mathew, Christopher G., Palmer, Colin N.A., Plomin, Robert, Rautanen, Anna, Sawcer, Stephen J., Trembath, Richard C., Viswanathan, Ananth C., Wood, Nicholas W., Wilson, Mary E., Deloukas, Panos, Peltonen, Leena, Christiansen, Frank, Witt, Campbell, Jeronimo, Selma M.B., Sundar, Shyam, Spencer, Chris C.A., Blackwell, Jenefer M., Donnelly, Peter
Publicado 2013

Transethnic meta-analysis of rare coding variants in PLCG2, ABI3, and TREM2 supports their general contribution to Alzheimer’s disease

por Dalmasso, Maria Carolina, Brusco, Luis Ignacio, Olivar, Natividad, Muchnik, Carolina, Hanses, Claudia, Milz, Esther, Becker, Julian, Heilmann-Heimbach, Stefanie, Hoffmann, Per, Prestia, Federico A., Galeano, Pablo, Avalos, Mariana Soledad Sanchez, Martinez, Luis Eduardo, Carulla, Mariana Estela, Azurmendi, Pablo Javier, Liberczuk, Cynthia, Fezza, Cristina, Sampaño, Marcelo, Fierens, Maria, Jemar, Guillermo, Solis, Patricia, Medel, Nancy, Lisso, Julieta, Sevillano, Zulma, Bosco, Paolo, Bossù, Paola, Spalletta, Gianfranco, Galimberti, Daniela, Mancuso, Michelangelo, Nacmias, Benedetta, Sorbi, Sandro, Mecocci, Patrizia, Pilotto, Alberto, Caffarra, Paolo, Panza, Francesco, Bullido, Maria, Clarimon, Jordi, Sánchez-Juan, Pascual, Coto, Eliecer, Sanchez-Garcia, Florentino, Graff, Caroline, Ingelsson, Martin, Bellenguez, Céline, Castaño, Eduardo Miguel, Kairiyama, Claudia, Politis, Daniel Gustavo, Kochen, Silvia, Scaro, Horacio, Maier, Wolfgang, Jessen, Frank, Mangone, Carlos Alberto, Lambert, Jean-Charles, Morelli, Laura, Ramirez, Alfredo
Publicado 2019

The correlation between reading and mathematics ability at age twelve has a substantial genetic component

por Davis, Oliver S. P., Band, Gavin, Pirinen, Matti, Haworth, Claire M. A., Meaburn, Emma L., Kovas, Yulia, Harlaar, Nicole, Docherty, Sophia J., Hanscombe, Ken B., Trzaskowski, Maciej, Curtis, Charles J. C., Strange, Amy, Freeman, Colin, Bellenguez, Céline, Su, Zhan, Pearson, Richard, Vukcevic, Damjan, Langford, Cordelia, Deloukas, Panos, Hunt, Sarah, Gray, Emma, Dronov, Serge, Potter, Simon C., Tashakkori-Ghanbaria, Avazeh, Edkins, Sarah, Bumpstead, Suzannah J., Blackwell, Jenefer M., Bramon, Elvira, Brown, Matthew A., Casas, Juan P., Corvin, Aiden, Duncanson, Audrey, Jankowski, Janusz A. Z., Markus, Hugh S., Mathew, Christopher G., Palmer, Colin N. A., Rautanen, Anna, Sawcer, Stephen J., Trembath, Richard C., Viswanathan, Ananth C., Wood, Nicholas W., Barroso, Ines, Peltonen, Leena, Dale, Philip S., Petrill, Stephen A., Schalkwyk, Leonard S., Craig, Ian W., Lewis, Cathryn M., Price, Thomas S., Donnelly, Peter, Plomin, Robert, Spencer, Chris C. A.
Publicado 2014

Common Genetic Determinants of Intraocular Pressure and Primary Open-Angle Glaucoma

por van Koolwijk, Leonieke M. E., Ramdas, Wishal D., Ikram, M. Kamran, Jansonius, Nomdo M., Pasutto, Francesca, Hysi, Pirro G., Macgregor, Stuart, Janssen, Sarah F., Hewitt, Alex W., Viswanathan, Ananth C., ten Brink, Jacoline B., Hosseini, S. Mohsen, Amin, Najaf, Despriet, Dominiek D. G., Willemse-Assink, Jacqueline J. M., Kramer, Rogier, Rivadeneira, Fernando, Struchalin, Maksim, Aulchenko, Yurii S., Weisschuh, Nicole, Zenkel, Matthias, Mardin, Christian Y., Gramer, Eugen, Welge-Lüssen, Ulrich, Montgomery, Grant W., Carbonaro, Francis, Young, Terri L., Bellenguez, Céline, McGuffin, Peter, Foster, Paul J., Topouzis, Fotis, Mitchell, Paul, Wang, Jie Jin, Wong, Tien Y., Czudowska, Monika A., Hofman, Albert, Uitterlinden, Andre G., Wolfs, Roger C. W., de Jong, Paulus T. V. M., Oostra, Ben A., Paterson, Andrew D., Mackey, David A., Bergen, Arthur A. B., Reis, André, Hammond, Christopher J., Vingerling, Johannes R., Lemij, Hans G., Klaver, Caroline C. W., van Duijn, Cornelia M.
Publicado 2012

Polymorphism in a lincRNA Associates with a Doubled Risk of Pneumococcal Bacteremia in Kenyan Children

por Rautanen, Anna, Pirinen, Matti, Mills, Tara C., Rockett, Kirk A., Strange, Amy, Ndungu, Anne W., Naranbhai, Vivek, Gilchrist, James J., Bellenguez, Céline, Freeman, Colin, Band, Gavin, Bumpstead, Suzannah J., Edkins, Sarah, Giannoulatou, Eleni, Gray, Emma, Dronov, Serge, Hunt, Sarah E., Langford, Cordelia, Pearson, Richard D., Su, Zhan, Vukcevic, Damjan, Macharia, Alex W., Uyoga, Sophie, Ndila, Carolyne, Mturi, Neema, Njuguna, Patricia, Mohammed, Shebe, Berkley, James A., Mwangi, Isaiah, Mwarumba, Salim, Kitsao, Barnes S., Lowe, Brett S., Morpeth, Susan C., Khandwalla, Iqbal, Blackwell, Jenefer M., Bramon, Elvira, Brown, Matthew A., Casas, Juan P., Corvin, Aiden, Duncanson, Audrey, Jankowski, Janusz, Markus, Hugh S., Mathew, Christopher G., Palmer, Colin N.A., Plomin, Robert, Sawcer, Stephen J., Trembath, Richard C., Viswanathan, Ananth C., Wood, Nicholas W., Deloukas, Panos, Peltonen, Leena, Williams, Thomas N., Scott, J. Anthony G., Chapman, Stephen J., Donnelly, Peter, Hill, Adrian V.S., Spencer, Chris C.A.
Publicado 2016

Genome-wide association study of intraocular pressure identifies the GLCCI1/ICA1 region as a glaucoma susceptibility locus

por Strange, Amy, Bellenguez, Céline, Sim, Xueling, Luben, Robert, Hysi, Pirro G., Ramdas, Wishal D., van Koolwijk, Leonieke M.E., Freeman, Colin, Pirinen, Matti, Su, Zhan, Band, Gavin, Pearson, Richard, Vukcevic, Damjan, Langford, Cordelia, Deloukas, Panos, Hunt, Sarah, Gray, Emma, Dronov, Serge, Potter, Simon C., Tashakkori-Ghanbaria, Avazeh, Edkins, Sarah, Bumpstead, Suzannah J., Blackwell, Jenefer M., Bramon, Elvira, Brown, Matthew A., Casas, Juan P., Corvin, Aiden, Duncanson, Audrey, Jankowski, Janusz A.Z., Markus, Hugh S., Mathew, Christopher G., Palmer, Colin N.A., Plomin, Robert, Rautanen, Anna, Sawcer, Stephen J., Trembath, Richard C., Wood, Nicholas W., Barroso, Ines, Peltonen, Leena, Healey, Paul, McGuffin, Peter, Topouzis, Fotis, Klaver, Caroline C.W., van Duijn, Cornelia M., Mackey, David A., Young, Terri L., Hammond, Christopher J., Khaw, Kay-Tee, Wareham, Nick, Wang, Jie Jin, Wong, Tien Y., Foster, Paul J., Mitchell, Paul, Spencer, Chris C.A., Donnelly, Peter, Viswanathan, Ananth C.
Publicado 2013

Genetic Associations Between Modifiable Risk Factors and Alzheimer Disease

por Luo, Jiao, Thomassen, Jesper Qvist, Bellenguez, Céline, Grenier-Boley, Benjamin, de Rojas, Itziar, Castillo, Atahualpa, Parveen, Kayenat, Küçükali, Fahri, Nicolas, Aude, Peters, Oliver, Schneider, Anja, Dichgans, Martin, Rujescu, Dan, Scherbaum, Norbert, Jürgen, Deckert, Riedel-Heller, Steffi, Hausner, Lucrezia, Porcel, Laura Molina, Düzel, Emrah, Grimmer, Timo, Wiltfang, Jens, Heilmann-Heimbach, Stefanie, Moebus, Susanne, Tegos, Thomas, Scarmeas, Nikolaos, Clarimon, Jordi, Moreno, Fermin, Pérez-Tur, Jordi, Bullido, María J., Pastor, Pau, Sánchez-Valle, Raquel, Álvarez, Victoria, Boada, Mercè, García-González, Pablo, Puerta, Raquel, Mir, Pablo, Real, Luis M., Piñol-Ripoll, Gerard, García-Alberca, Jose María, Royo, Jose Luís, Rodriguez-Rodriguez, Eloy, Soininen, Hilkka, Kuulasmaa, Teemu, de Mendonça, Alexandre, Mehrabian, Shima, Hort, Jakub, Vyhnalek, Martin, van der Lee, Sven, Graff, Caroline, Papenberg, Goran, Giedraitis, Vilmantas, Boland, Anne, Bacq-Daian, Delphine, Deleuze, Jean-François, Nicolas, Gael, Dufouil, Carole, Pasquier, Florence, Hanon, Olivier, Debette, Stéphanie, Grünblatt, Edna, Popp, Julius, Benussi, Luisa, Galimberti, Daniela, Arosio, Beatrice, Mecocci, Patrizia, Solfrizzi, Vincenzo, Parnetti, Lucilla, Squassina, Alessio, Tremolizzo, Lucio, Borroni, Barbara, Nacmias, Benedetta, Sorbi, Sandro, Caffarra, Paolo, Seripa, Davide, Rainero, Innocenzo, Daniele, Antonio, Masullo, Carlo, Spalletta, Gianfranco, Williams, Julie, Amouyel, Philippe, Jessen, Frank, Kehoe, Patrick, Magda, Tsolaki, Rossi, Giacomina, Sánchez-Juan, Pascual, Sleegers, Kristel, Ingelsson, Martin, Andreassen, Ole A., Hiltunen, Mikko, Van Duijn, Cornelia, Sims, Rebecca, van der Flier, Wiesje, Ruiz, Agustín, Ramirez, Alfredo, Lambert, Jean-Charles, Frikke-Schmidt, Ruth
Publicado 2023

Genome-wide analysis of multiethnic cohorts identifies new loci influencing intraocular pressure and susceptibility to glaucoma

por Hysi, Pirro G, Cheng, Ching-Yu, Springelkamp, Henriët, Macgregor, Stuart, Bailey, Jessica N Cooke, Wojciechowski, Robert, Vitart, Veronique, Nag, Abhishek, Hewitt, Alex W, Höhn, René, Venturini, Cristina, Mirshahi, Alireza, Ramdas, Wishal D., Thorleifsson, Gudmar, Vithana, Eranga, Khor, Chiea-Chuen, Stefansson, Arni B, Liao, Jiemin, Haines, Jonathan L, Amin, Najaf, Wang, Ya Xing, Wild, Philipp S, Ozel, Ayse B, Li, Jun Z, Fleck, Brian W, Zeller, Tanja, Staffieri, Sandra E, Teo, Yik-Ying, Cuellar-Partida, Gabriel, Luo, Xiaoyan, Allingham, R Rand, Richards, Julia E, Senft, Andrea, Karssen, Lennart C, Zheng, Yingfeng, Bellenguez, Céline, Xu, Liang, Iglesias, Adriana I, Wilson, James F, Kang, Jae H, van Leeuwen, Elisabeth M, Jonsson, Vesteinn, Thorsteinsdottir, Unnur, Despriet, Dominiek D.G., Ennis, Sarah, Moroi, Sayoko E, Martin, Nicholas G, Jansonius, Nomdo M, Yazar, Seyhan, Tai, E-Shyong, Amouyel, Philippe, Kirwan, James, van Koolwijk, Leonieke M.E., Hauser, Michael A, Jonasson, Fridbert, Leo, Paul, Loomis, Stephanie J, Fogarty, Rhys, Rivadeneira, Fernando, Kearns, Lisa, Lackner, Karl J, de Jong, Paulus T.V.M., Simpson, Claire L, Pennell, Craig E, Oostra, Ben A, Uitterlinden, André G, Saw, Seang-Mei, Lotery, Andrew J, Bailey-Wilson, Joan E, Hofman, Albert, Vingerling, Johannes R, Maubaret, Cécilia, Pfeiffer, Norbert, Wolfs, Roger C.W., Lemij, Hans G, Young, Terri L, Pasquale, Louis R, Delcourt, Cécile, Spector, Timothy D, Klaver, Caroline C.W., Small, Kerrin S, Burdon, Kathryn P, Stefansson, Kari, Wong, Tien-Yin, Viswanathan, Ananth, Mackey, David A, Craig, Jamie E, Wiggs, Janey L, van Duijn, Cornelia M, Hammond, Christopher J, Aung, Tin
Publicado 2014