Structural Study of a New MbtI-Inhibitor Complex: Towards an Optimized Model for Structure-Based Drug Discovery

por Mori, Matteo, Villa, Stefania, Chiarelli, Laurent R., Meneghetti, Fiorella, Bellinzoni, Marco
Publicado 2023

Structural Basis for the Binding of Allosteric Activators Leucine and ADP to Mammalian Glutamate Dehydrogenase

por Aleshin, Vasily A., Bunik, Victoria I., Bruch, Eduardo M., Bellinzoni, Marco
Publicado 2022

Selective Inhibition of 2-Oxoglutarate and 2-Oxoadipate Dehydrogenases by the Phosphonate Analogs of Their 2-Oxo Acid Substrates

por Artiukhov, Artem V., Kazantsev, Alexey V., Lukashev, Nikolay V., Bellinzoni, Marco, Bunik, Victoria I.
Publicado 2021

Characteristics of the GlnH and GlnX Signal Transduction Proteins Controlling PknG-Mediated Phosphorylation of OdhI and 2-Oxoglutarate Dehydrogenase Activity in Corynebacterium glu...

por Sundermeyer, Lea, Bosco, Graziella, Gujar, Srushti, Brocker, Melanie, Baumgart, Meike, Willbold, Dieter, Weiergräber, Oliver H., Bellinzoni, Marco, Bott, Michael
Publicado 2022

High resolution cryo-EM and crystallographic snapshots of the actinobacterial two-in-one 2-oxoglutarate dehydrogenase

por Yang, Lu, Wagner, Tristan, Mechaly, Ariel, Boyko, Alexandra, Bruch, Eduardo M., Megrian, Daniela, Gubellini, Francesca, Alzari, Pedro M., Bellinzoni, Marco
Publicado 2023

The Antibacterial Type VII Secretion System of Bacillus subtilis: Structure and Interactions of the Pseudokinase YukC/EssB

por Tassinari, Matteo, Doan, Thierry, Bellinzoni, Marco, Chabalier, Maïalene, Ben-Assaya, Mathilde, Martinez, Mariano, Gaday, Quentin, Alzari, Pedro M., Cascales, Eric, Fronzes, Rémi, Gubellini, Francesca
Publicado 2022

Contactin 4, -5 and -6 differentially regulate neuritogenesis while they display identical PTPRG binding sites

por Mercati, Oriane, Danckaert, Anne, André-Leroux, Gwénaëlle, Bellinzoni, Marco, Gouder, Laura, Watanabe, Kazutada, Shimoda, Yasushi, Grailhe, Régis, De Chaumont, Fabrice, Bourgeron, Thomas, Cloëz-Tayarani, Isabelle
Publicado 2013

A Tetratricopeptide Repeat Scaffold Couples Signal Detection to OdhI Phosphorylation in Metabolic Control by the Protein Kinase PknG

por Lisa, María-Natalia, Sogues, Adrià, Barilone, Nathalie, Baumgart, Meike, Gil, Magdalena, Graña, Martín, Durán, Rosario, Biondi, Ricardo M., Bellinzoni, Marco, Bott, Michael, Alzari, Pedro M.
Publicado 2021

Shedding X-ray Light on the Role of Magnesium in the Activity of Mycobacterium tuberculosis Salicylate Synthase (MbtI) for Drug Design

por Mori, Matteo, Stelitano, Giovanni, Gelain, Arianna, Pini, Elena, Chiarelli, Laurent R., Sammartino, José C., Poli, Giulio, Tuccinardi, Tiziano, Beretta, Giangiacomo, Porta, Alessio, Bellinzoni, Marco, Villa, Stefania, Meneghetti, Fiorella
Publicado 2020

New insight into structure-activity of furan-based salicylate synthase (MbtI) inhibitors as potential antitubercular agents

por Chiarelli, Laurent R., Mori, Matteo, Beretta, Giangiacomo, Gelain, Arianna, Pini, Elena, Sammartino, Josè Camilla, Stelitano, Giovanni, Barlocco, Daniela, Costantino, Luca, Lapillo, Margherita, Poli, Giulio, Caligiuri, Isabella, Rizzolio, Flavio, Bellinzoni, Marco, Tuccinardi, Tiziano, Villa, Stefania, Meneghetti, Fiorella
Publicado 2019

PknG senses amino acid availability to control metabolism and virulence of Mycobacterium tuberculosis

por Rieck, Barbara, Degiacomi, Giulia, Zimmermann, Michael, Cascioferro, Alessandro, Boldrin, Francesca, Lazar-Adler, Natalie R., Bottrill, Andrew R., le Chevalier, Fabien, Frigui, Wafa, Bellinzoni, Marco, Lisa, María-Natalia, Alzari, Pedro M., Nguyen, Liem, Brosch, Roland, Sauer, Uwe, Manganelli, Riccardo, O’Hare, Helen M.
Publicado 2017

Thiophenecarboxamide Derivatives Activated by EthA Kill Mycobacterium tuberculosis by Inhibiting the CTP Synthetase PyrG

por Mori, Giorgia, Chiarelli, Laurent R., Esposito, Marta, Makarov, Vadim, Bellinzoni, Marco, Hartkoorn, Ruben C., Degiacomi, Giulia, Boldrin, Francesca, Ekins, Sean, de Jesus Lopes Ribeiro, Ana Luisa, Marino, Leonardo B., Centárová, Ivana, Svetlíková, Zuzana, Blaško, Jaroslav, Kazakova, Elena, Lepioshkin, Alexander, Barilone, Nathalie, Zanoni, Giuseppe, Porta, Alessio, Fondi, Marco, Fani, Renato, Baulard, Alain R., Mikušová, Katarína, Alzari, Pedro M., Manganelli, Riccardo, de Carvalho, Luiz Pedro S., Riccardi, Giovanna, Cole, Stewart T., Pasca, Maria Rosalia
Publicado 2015