Ultramicroscopy as a novel tool to unravel the tropism of AAV gene therapy vectors in the brain

por Alves, Sandro, Bode, Julia, Bemelmans, Alexis-Pierre, von Kalle, Christof, Cartier, Nathalie, Tews, Björn
Publicado 2016

rAAV-Mediated Cochlear Gene Therapy: Prospects and Challenges for Clinical Application

por Blanc, Fabian, Mondain, Michel, Bemelmans, Alexis-Pierre, Affortit, Corentin, Puel, Jean-Luc, Wang, Jing
Publicado 2020

mRNA trans‐splicing in gene therapy for genetic diseases

por Berger, Adeline, Maire, Séverine, Gaillard, Marie‐Claude, Sahel, José‐Alain, Hantraye, Philippe, Bemelmans, Alexis‐Pierre
Publicado 2016

Time-Course of Alterations in the Endocannabinoid System after Viral-Mediated Overexpression of α-Synuclein in the Rat Brain

por Kelly, Rachel, Bemelmans, Alexis-Pierre, Joséphine, Charlène, Brouillet, Emmanuel, McKernan, Declan P., Dowd, Eilís
Publicado 2022

A Single Cisterna Magna Injection of AAV Leads to Binaural Transduction in Mice

por Blanc, Fabian, Bemelmans, Alexis-Pierre, Affortit, Corentin, Joséphine, Charlène, Puel, Jean-Luc, Mondain, Michel, Wang, Jing
Publicado 2022

Gene Therapy Regenerates Protein Expression in Cone Photoreceptors in Rpe65(R91W/R91W) Mice

por Kostic, Corinne, Crippa, Sylvain Vincent, Pignat, Vérène, Bemelmans, Alexis-Pierre, Samardzija, Marijana, Grimm, Christian, Wenzel, Andreas, Arsenijevic, Yvan
Publicado 2011

Upregulation of astroglial connexin 30 impairs hippocampal synaptic activity and recognition memory

por Hardy, Eléonore, Moulard, Julien, Walter, Augustin, Ezan, Pascal, Bemelmans, Alexis-Pierre, Mouthon, Franck, Charvériat, Mathieu, Rouach, Nathalie, Rancillac, Armelle
Publicado 2023

A Single Intravenous AAV9 Injection Mediates Bilateral Gene Transfer to the Adult Mouse Retina

por Bemelmans, Alexis-Pierre, Duqué, Sandra, Rivière, Christel, Astord, Stéphanie, Desrosiers, Mélissa, Marais, Thibault, Sahel, José-Alain, Voit, Thomas, Barkats, Martine
Publicado 2013

Repair of Rhodopsin mRNA by Spliceosome-Mediated RNA Trans-Splicing: A New Approach for Autosomal Dominant Retinitis Pigmentosa

por Berger, Adeline, Lorain, Stéphanie, Joséphine, Charlène, Desrosiers, Melissa, Peccate, Cécile, Voit, Thomas, Garcia, Luis, Sahel, José-Alain, Bemelmans, Alexis-Pierre
Publicado 2015

Spectral-Domain Optical Coherence Tomography of the Rodent Eye: Highlighting Layers of the Outer Retina Using Signal Averaging and Comparison with Histology

por Berger, Adeline, Cavallero, Sophie, Dominguez, Elisa, Barbe, Peggy, Simonutti, Manuel, Sahel, José-Alain, Sennlaub, Florian, Raoul, William, Paques, Michel, Bemelmans, Alexis-Pierre
Publicado 2014

Connexin 30 controls astroglial polarization during postnatal brain development

por Ghézali, Grégory, Calvo, Charles-Félix, Pillet, Laure-Elise, Llense, Flora, Ezan, Pascal, Pannasch, Ulrike, Bemelmans, Alexis-Pierre, Etienne Manneville, Sandrine, Rouach, Nathalie
Publicado 2018

The Small Molecule Alpha-Synuclein Aggregator, FN075, Enhances Alpha-Synuclein Pathology in Subclinical AAV Rat Models

por Kelly, Rachel, Cairns, Andrew G., Ådén, Jörgen, Almqvist, Fredrik, Bemelmans, Alexis-Pierre, Brouillet, Emmanuel, Patton, Tommy, McKernan, Declan P., Dowd, Eilís
Publicado 2021

Lentiviral Gene Transfer of Rpe65 Rescues Survival and Function of Cones in a Mouse Model of Leber Congenital Amaurosis

por Bemelmans, Alexis-Pierre, Kostic, Corinne, Crippa, Sylvain V, Hauswirth, William W, Lem, Janis, Munier, Francis L, Seeliger, Mathias W, Wenzel, Andreas, Arsenijevic, Yvan
Publicado 2006

Apolipoprotein E promotes subretinal mononuclear phagocyte survival and chronic inflammation in age-related macular degeneration

por Levy, Olivier, Calippe, Bertrand, Lavalette, Sophie, Hu, Shulong J, Raoul, William, Dominguez, Elisa, Housset, Michael, Paques, Michel, Sahel, José-Alain, Bemelmans, Alexis-Pierre, Combadiere, Christophe, Guillonneau, Xavier, Sennlaub, Florian
Publicado 2015

Deciphering the molecular basis of invasiveness in Sdhb-deficient cells

por Loriot, Céline, Domingues, Mélanie, Berger, Adeline, Menara, Mélanie, Ruel, Maëva, Morin, Aurélie, Castro-Vega, Luis-Jaime, Letouzé, Éric, Martinelli, Cosimo, Bemelmans, Alexis-Pierre, Larue, Lionel, Gimenez-Roqueplo, Anne-Paule, Favier, Judith
Publicado 2015

Physiological synaptic activity and recognition memory require astroglial glutamine

por Cheung, Giselle, Bataveljic, Danijela, Visser, Josien, Kumar, Naresh, Moulard, Julien, Dallérac, Glenn, Mozheiko, Daria, Rollenhagen, Astrid, Ezan, Pascal, Mongin, Cédric, Chever, Oana, Bemelmans, Alexis-Pierre, Lübke, Joachim, Leray, Isabelle, Rouach, Nathalie
Publicado 2022

The ribosome-associated protein RACK1 represses Kir4.1 translation in astrocytes and influences neuronal activity

por Oudart, Marc, Avila-Gutierrez, Katia, Moch, Clara, Dossi, Elena, Milior, Giampaolo, Boulay, Anne-Cécile, Gaudey, Mathis, Moulard, Julien, Lombard, Bérangère, Loew, Damarys, Bemelmans, Alexis-Pierre, Rouach, Nathalie, Chapat, Clément, Cohen-Salmon, Martine
Publicado 2023

Local Translation in Perisynaptic Astrocytic Processes Is Specific and Changes after Fear Conditioning

por Mazaré, Noémie, Oudart, Marc, Moulard, Julien, Cheung, Giselle, Tortuyaux, Romain, Mailly, Philippe, Mazaud, David, Bemelmans, Alexis-Pierre, Boulay, Anne-Cécile, Blugeon, Corinne, Jourdren, Laurent, Le Crom, Stéphane, Rouach, Nathalie, Cohen-Salmon, Martine
Publicado 2020

Alzheimer’s disease-like APP processing in wild-type mice identifies synaptic defects as initial steps of disease progression

por Audrain, Mickael, Fol, Romain, Dutar, Patrick, Potier, Brigitte, Billard, Jean-Marie, Flament, Julien, Alves, Sandro, Burlot, Marie-Anne, Dufayet-Chaffaud, Gaelle, Bemelmans, Alexis-Pierre, Valette, Julien, Hantraye, Philippe, Déglon, Nicole, Cartier, Nathalie, Braudeau, Jérome
Publicado 2016

Multicolor multiscale brain imaging with chromatic multiphoton serial microscopy

por Abdeladim, Lamiae, Matho, Katherine S., Clavreul, Solène, Mahou, Pierre, Sintes, Jean-Marc, Solinas, Xavier, Arganda-Carreras, Ignacio, Turney, Stephen G., Lichtman, Jeff W., Chessel, Anatole, Bemelmans, Alexis-Pierre, Loulier, Karine, Supatto, Willy, Livet, Jean, Beaurepaire, Emmanuel
Publicado 2019