Repurposing Potential of Riluzole as an ITAF Inhibitor in mTOR Therapy Resistant Glioblastoma

por Benavides-Serrato, Angelica, Saunders, Jacquelyn T., Holmes, Brent, Nishimura, Robert N., Lichtenstein, Alan, Gera, Joseph
Publicado 2020

mTORC2-mediated direct phosphorylation regulates YAP activity promoting glioblastoma growth and invasive characteristics

por Holmes, Brent, Benavides-Serrato, Angelica, Saunders, Jacquelyn T., Kumar, Sunil, Nishimura, Robert N., Gera, Joseph
Publicado 2021

mTORC2 modulates feedback regulation of p38 MAPK activity via DUSP10/MKP5 to confer differential responses to PP242 in glioblastoma

por Benavides-Serrato, Angelica, Anderson, Lauren, Holmes, Brent, Cloninger, Cheri, Artinian, Nicholas, Bashir, Tariq, Gera, Joseph
Publicado 2014

mTORC2/AKT/HSF1/HuR constitute a feed-forward loop regulating Rictor expression and tumor growth in glioblastoma

por Holmes, Brent, Benavides-Serrato, Angelica, Freeman, Ryan S., Landon, Kenna A., Bashir, Tariq, Nishimura, Robert N., Gera, Joseph
Publicado 2017

Translation of circHGF RNA encodes an HGF protein variant promoting glioblastoma growth through stimulation of c-MET

por Saunders, Jacquelyn T., Kumar, Sunil, Benavides-Serrato, Angelica, Holmes, Brent, Benavides, Kennedy E., Bashir, Muhammad T., Nishimura, Robert N., Gera, Joseph
Publicado 2023

Specific blockade of Rictor-mTOR association inhibits mTORC2 activity and is cytotoxic in glioblastoma

por Benavides-Serrato, Angelica, Lee, Jihye, Holmes, Brent, Landon, Kenna A., Bashir, Tariq, Jung, Michael E., Lichtenstein, Alan, Gera, Joseph
Publicado 2017

Correction: Specific blockade of Rictor-mTOR association inhibits mTORC2 activity and is cytotoxic in glioblastoma

por Benavides-Serrato, Angelica, Lee, Jihye, Holmes, Brent, Landon, Kenna A., Bashir, Tariq, Jung, Michael E., Lichtenstein, Alan, Gera, Joseph
Publicado 2019

Conditional Astroglial Rictor Overexpression Induces Malignant Glioma in Mice

por Bashir, Tariq, Cloninger, Cheri, Artinian, Nicholas, Anderson, Lauren, Bernath, Andrew, Holmes, Brent, Benavides-Serrato, Angelica, Sabha, Nesrin, Nishimura, Robert N., Guha, Abhijit, Gera, Joseph
Publicado 2012