1-(Benzo[d]thiazol-2-yl)-3-phenylureas as dual inhibitors of casein kinase 1 and ABAD enzymes for treatment of neurodegenerative disorders

por Benek, Ondrej, Hroch, Lukas, Aitken, Laura, Gunn-Moore, Frank, Vinklarova, Lucie, Kuca, Kamil, Perez, Daniel I., Perez, Concepcion, Martinez, Ana, Fisar, Zdenek, Musilek, Kamil
Publicado 2018

Novel Benzothiazole-Based Ureas as 17β-HSD10 Inhibitors, A Potential Alzheimer’s Disease Treatment

por Aitken, Laura, Benek, Ondrej, McKelvie, Brogan E., Hughes, Rebecca E., Hroch, Lukas, Schmidt, Monika, Major, Louise L., Vinklarova, Lucie, Kuca, Kamil, Smith, Terry K., Musilek, Kamil, Gunn-Moore, Frank J.
Publicado 2019

Benzothiazolyl Ureas are Low Micromolar and Uncompetitive Inhibitors of 17β-HSD10 with Implications to Alzheimer’s Disease Treatment

por Schmidt, Monika, Benek, Ondrej, Vinklarova, Lucie, Hrabinova, Martina, Zemanova, Lucie, Chribek, Matej, Kralova, Vendula, Hroch, Lukas, Dolezal, Rafael, Lycka, Antonin, Prchal, Lukas, Jun, Daniel, Aitken, Laura, Gunn-Moore, Frank, Kuca, Kamil, Musilek, Kamil
Publicado 2020

Exploring the Chemical Space of Benzothiazole-Based DNA Gyrase B Inhibitors

por Skok, Žiga, Barančoková, Michaela, Benek, Ondřej, Cruz, Cristina Durante, Tammela, Päivi, Tomašič, Tihomir, Zidar, Nace, Mašič, Lucija Peterlin, Zega, Anamarija, Stevenson, Clare E. M., Mundy, Julia E. A., Lawson, David M., Maxwell, Anthony, Kikelj, Danijel, Ilaš, Janez
Publicado 2020