Clearance (née Rowland) concepts: a downdate and an update

por Benet, Leslie Z.
Publicado 2010

The Role of Transporters in the Pharmacokinetics of Orally Administered Drugs

por Shugarts, Sarah, Benet, Leslie Z.
Publicado 2009

Distinguishing between the Permeability Relationships with Absorption and Metabolism To Improve BCS and BDDCS Predictions in Early Drug Discovery

por Larregieu, Caroline A., Benet, Leslie Z.
Publicado 2014

Is Ciprofloxacin a Substrate of P-glycoprotein?

por Park, Miki Susanto, Okochi, Hideaki, Benet, Leslie Z
Publicado 2011

State of the Art and Uses for the Biopharmaceutics Drug Disposition Classification System (BDDCS): New Additions, Revisions, and Citation References

por Bocci, Giovanni, Oprea, Tudor I., Benet, Leslie Z.
Publicado 2022

Volume of Distribution is Unaffected by Metabolic Drug–Drug Interactions

por Sodhi, Jasleen K., Huang, Caroline H., Benet, Leslie Z.
Publicado 2020

There is Only One Valid Definition of Clearance: Critical Examination of Clearance Concepts Reveals the Potential for Errors in Clinical Drug Dosing Decisions

por Benet, Leslie Z., Sodhi, Jasleen K., Makrygiorgos, George, Mesbah, Ali
Publicado 2021

Using an animal model to predict the effective human dose for oral multiple sclerosis drugs

por Liu, Wei, Yu, Zhiheng, Wang, Ziyu, Waubant, Emmanuelle L., Zhai, Suodi, Benet, Leslie Z.
Publicado 2022

Mouse liver repopulation with hepatocytes generated from human fibroblasts

por Zhu, Saiyong, Rezvani, Milad, Harbell, Jack, Mattis, Aras N., Wolfe, Alan R., Benet, Leslie Z., Willenbring, Holger, Ding, Sheng
Publicado 2014

Local delivery of hormonal therapy with silastic tubing for prevention and treatment of breast cancer

por Park, Jeenah, Thomas, Scott, Zhong, Allison Y., Wolfe, Alan R., Krings, Gregor, Terranova-Barberio, Manuela, Pawlowska, Nela, Benet, Leslie Z., Munster, Pamela N.
Publicado 2018

TPT sulfonate, a single, oral dose schistosomicidal prodrug: In vivo efficacy, disposition and metabolic profiling

por Wolfe, Alan R., Neitz, R. Jeffrey, Burlingame, Mark, Suzuki, Brian M., Lim, KC, Scheideler, Mark, Nelson, David L., Benet, Leslie Z., Caffrey, Conor R.
Publicado 2018

Ascorbic acid metabolites are involved in intraocular pressure control in the general population

por Hysi, Pirro G., Khawaja, Anthony P., Menni, Cristina, Tamraz, Bani, Wareham, Nick, Khaw, Kay-Tee, Foster, Paul J., Benet, Leslie Z., Spector, Tim D., Hammond, Chris J.
Publicado 2018

Development and Validation of an Immunoassay for Tenofovir in Urine as a Real-Time Metric of Antiretroviral Adherence

por Gandhi, Monica, Bacchetti, Peter, Rodrigues, Warren C., Spinelli, Matthew, Koss, Catherine A., Drain, Paul K., Baeten, Jared M., Mugo, Nelly R., Ngure, Kenneth, Benet, Leslie Z., Okochi, Hideaki, Wang, Guohong, Vincent, Michael
Publicado 2018