A heme•DNAzyme activated by hydrogen peroxide catalytically oxidizes thioethers by direct oxygen atom transfer rather than by a Compound I-like intermediate

por Shumayrikh, Nisreen M, Warren, Jeffrey J, Bennet, Andrew J, Sen, Dipankar
Publicado 2021

Design and synthesis of constrained bicyclic molecules as candidate inhibitors of influenza A neuraminidase

por Colombo, Cinzia, Podlipnik, Črtomir, Lo Presti, Leonardo, Niikura, Masahiro, Bennet, Andrew J., Bernardi, Anna
Publicado 2018

Glycoside hydrolase stabilization of transition state charge: new directions for inhibitor design

por Ren, Weiwu, Farren-Dai, Marco, Sannikova, Natalia, Świderek, Katarzyna, Wang, Yang, Akintola, Oluwafemi, Britton, Robert, Moliner, Vicent, Bennet, Andrew J.
Publicado 2020

Structural Snapshots for Mechanism‐Based Inactivation of a Glycoside Hydrolase by Cyclopropyl Carbasugars

por Adamson, Christopher, Pengelly, Robert J., Shamsi Kazem Abadi, Saeideh, Chakladar, Saswati, Draper, Jason, Britton, Robert, Gloster, Tracey M., Bennet, Andrew J.
Publicado 2016

The Aspergillus fumigatus Sialidase (Kdnase) Contributes to Cell Wall Integrity and Virulence in Amphotericin B-Treated Mice

por Nesbitt, Jason R., Steves, Elizabeth Y., Schonhofer, Cole R., Cait, Alissa, Manku, Sukhbir S., Yeung, Juliana H. F., Bennet, Andrew J., McNagny, Kelly M., Choy, Jonathan C., Hughes, Michael R., Moore, Margo M.
Publicado 2018

Revealing the mechanism for covalent inhibition of glycoside hydrolases by carbasugars at an atomic level

por Ren, Weiwu, Pengelly, Robert, Farren-Dai, Marco, Shamsi Kazem Abadi, Saeideh, Oehler, Verena, Akintola, Oluwafemi, Draper, Jason, Meanwell, Michael, Chakladar, Saswati, Świderek, Katarzyna, Moliner, Vicent, Britton, Robert, Gloster, Tracey M., Bennet, Andrew J.
Publicado 2018

Author Correction: Revealing the mechanism for covalent inhibition of glycoside hydrolases by carbasugars at an atomic level

por Ren, Weiwu, Pengelly, Robert, Farren-Dai, Marco, Abadi, Saeideh Shamsi Kazem, Oehler, Verena, Akintola, Oluwafemi, Draper, Jason, Meanwell, Michael, Chakladar, Saswati, Świderek, Katarzyna, Moliner, Vicent, Britton, Robert, Gloster, Tracey M., Bennet, Andrew J.
Publicado 2018

An Epoxide Intermediate in Glycosidase Catalysis

por Sobala, Lukasz F., Speciale, Gaetano, Zhu, Sha, Raich, Lluís, Sannikova, Natalia, Thompson, Andrew J., Hakki, Zalihe, Lu, Dan, Shamsi Kazem Abadi, Saeideh, Lewis, Andrew R., Rojas-Cervellera, Víctor, Bernardo-Seisdedos, Ganeko, Zhang, Yongmin, Millet, Oscar, Jiménez-Barbero, Jesús, Bennet, Andrew J., Sollogoub, Matthieu, Rovira, Carme, Davies, Gideon J., Williams, Spencer J.
Publicado 2020