Degradation of D-2-hydroxyglutarate in the presence of isocitrate dehydrogenase mutations

por Berger, Raffaela S., Ellmann, Lisa, Reinders, Joerg, Kreutz, Marina, Stempfl, Thomas, Oefner, Peter J., Dettmer, Katja
Publicado 2019

Isotope Ratio Outlier Analysis (IROA) for HPLC–TOFMS-Based Metabolomics of Human Urine

por Fadil, Fadi, Samol, Claudia, Berger, Raffaela S., Kellermeier, Fabian, Gronwald, Wolfram, Oefner, Peter J., Dettmer, Katja
Publicado 2022

Optimized Protocol for the In Situ Derivatization of Glutathione with N-Ethylmaleimide in Cultured Cells and the Simultaneous Determination of Glutathione/Glutathione Disulfide Rat...

por Sun, Xueni, Berger, Raffaela S., Heinrich, Paul, Marchiq, Ibtissam, Pouyssegur, Jacques, Renner, Kathrin, Oefner, Peter J., Dettmer, Katja
Publicado 2020

Empagliflozin Reduces Renal Hyperfiltration in Response to Uninephrectomy, but Is Not Nephroprotective in UNx/DOCA/Salt Mouse Models

por Tauber, Philipp, Sinha, Frederick, Berger, Raffaela S., Gronwald, Wolfram, Dettmer, Katja, Kuhn, Michaela, Trum, Maximilian, Maier, Lars S., Wagner, Stefan, Schweda, Frank
Publicado 2021

D-2-hydroxyglutarate interferes with HIF-1α stability skewing T-cell metabolism towards oxidative phosphorylation and impairing Th17 polarization

por Böttcher, Martin, Renner, Kathrin, Berger, Raffaela, Mentz, Kristin, Thomas, Simone, Cardenas-Conejo, Zugey Elizabeth, Dettmer, Katja, Oefner, Peter J., Mackensen, Andreas, Kreutz, Marina, Mougiakakos, Dimitrios
Publicado 2018

Acidic Microenvironments Found in Cutaneous Leishmania Lesions Curtail NO-Dependent Antiparasitic Macrophage Activity

por Frick, Linus, Hinterland, Linda, Renner, Kathrin, Vogl, Marion, Babl, Nathalie, Heckscher, Simon, Weigert, Anna, Weiß, Susanne, Gläsner, Joachim, Berger, Raffaela, Oefner, Peter J., Dettmer, Katja, Kreutz, Marina, Schatz, Valentin, Jantsch, Jonathan
Publicado 2022

Lactonization of the Oncometabolite D-2-Hydroxyglutarate Produces a Novel Endogenous Metabolite

por Berger, Raffaela S., Wachsmuth, Christian J., Waldhier, Magdalena C., Renner-Sattler, Kathrin, Thomas, Simone, Chaturvedi, Anuhar, Niller, Hans-Helmut, Bumes, Elisabeth, Hau, Peter, Proescholdt, Martin, Gronwald, Wolfram, Heuser, Michael, Kreutz, Marina, Oefner, Peter J., Dettmer, Katja
Publicado 2021

Macrophages inhibit Coxiella burnetii by the ACOD1‐itaconate pathway for containment of Q fever

por Kohl, Lisa, Siddique, Md Nur A Alam, Bodendorfer, Barbara, Berger, Raffaela, Preikschat, Annica, Daniel, Christoph, Ölke, Martha, Liebler‐Tenorio, Elisabeth, Schulze‐Luehrmann, Jan, Mauermeir, Michael, Yang, Kai‐Ting, Hayek, Inaya, Szperlinski, Manuela, Andrack, Jennifer, Schleicher, Ulrike, Bozec, Aline, Krönke, Gerhard, Murray, Peter J, Wirtz, Stefan, Yamamoto, Masahiro, Schatz, Valentin, Jantsch, Jonathan, Oefner, Peter, Degrandi, Daniel, Pfeffer, Klaus, Mertens‐Scholz, Katja, Rauber, Simon, Bogdan, Christian, Dettmer, Katja, Lührmann, Anja, Lang, Roland
Publicado 2022