Receptor-interacting protein 1 kinase inhibition therapeutically ameliorates experimental T cell-dependent colitis in mice

por Gobbetti, Thomas, Berger, Scott B., Fountain, Kathryn, Slocombe, Tom, Rowles, Alison, Pearse, Gail, Harada, Isobel, Bertin, John, Haynes, Andrea C., Beal, Allison M.
Publicado 2020

A novel isoform of the Ly108 gene ameliorates murine lupus

por Keszei, Marton, Detre, Cynthia, Rietdijk, Svend T., Muñoz, Pilar, Romero, Xavier, Berger, Scott B., Calpe, Silvia, Liao, Gongxian, Castro, Wilson, Julien, Aimee, Wu, Ying-Yu, Shin, Dong-Mi, Sancho, Jaime, Zubiaur, Mercedes, Morse, Herbert C., Morel, Laurence, Engel, Pablo, Wang, Ninghai, Terhorst, Cox
Publicado 2011

MALT1 Protease Activity Is Required for Innate and Adaptive Immune Responses

por Yu, Jong W., Hoffman, Sandy, Beal, Allison M., Dykon, Angela, Ringenberg, Michael A., Hughes, Anna C., Dare, Lauren, Anderson, Amber D., Finger, Joshua, Kasparcova, Viera, Rickard, David, Berger, Scott B., Ramanjulu, Joshi, Emery, John G., Gough, Peter J., Bertin, John, Foley, Kevin P.
Publicado 2015

RIPK1-dependent apoptosis bypasses pathogen blockade of innate signaling to promote immune defense

por Peterson, Lance W., Philip, Naomi H., DeLaney, Alexandra, Wynosky-Dolfi, Meghan A., Asklof, Kendra, Gray, Falon, Choa, Ruth, Bjanes, Elisabet, Buza, Elisabeth L., Hu, Baofeng, Dillon, Christopher P., Green, Douglas R., Berger, Scott B., Gough, Peter J., Bertin, John, Brodsky, Igor E.
Publicado 2017

Identification of a RIP1 Kinase Inhibitor Clinical Candidate (GSK3145095) for the Treatment of Pancreatic Cancer

por Harris, Philip A., Marinis, Jill M., Lich, John D., Berger, Scott B., Chirala, Anirudh, Cox, Julie A., Eidam, Patrick M., Finger, Joshua N., Gough, Peter J., Jeong, Jae U., Kang, James, Kasparcova, Viera, Leister, Lara K., Mahajan, Mukesh K., Miller, George, Nagilla, Rakesh, Ouellette, Michael T., Reilly, Michael A., Rendina, Alan R., Rivera, Elizabeth J., Sun, Helen H., Thorpe, James H., Totoritis, Rachel D., Wang, Wei, Wu, Dongling, Zhang, Daohua, Bertin, John, Marquis, Robert W.
Publicado 2019

Identification of small-molecule protein–protein interaction inhibitors for NKG2D

por Thompson, Aaron A., Harbut, Michael B., Kung, Pei-Pei, Karpowich, Nathan K., Branson, Jeffrey D., Grant, Joanna C., Hagan, Deborah, Pascual, Heather A., Bai, Guoyun, Zavareh, Reza Beheshti, Coate, Heather R., Collins, Bernard C., Côte, Marjorie, Gelin, Christine F., Damm-Ganamet, Kelly L., Gholami, Hadi, Huff, Adam R., Limon, Luis, Lumb, Kevin J., Mak, Puiying A., Nakafuku, Kohki M., Price, Edmund V., Shih, Amy Y., Tootoonchi, Mandana, Vellore, Nadeem A., Wang, Jocelyn, Wei, Na, Ziff, Jeannie, Berger, Scott B., Edwards, James P., Gardet, Agnès, Sun, Siquan, Towne, Jennifer E., Venable, Jennifer D., Shi, Zhicai, Venkatesan, Hariharan, Rives, Marie-Laure, Sharma, Sujata, Shireman, Brock T., Allen, Samantha J.
Publicado 2023