Poisoning Pyridoxal 5-Phosphate-Dependent Enzymes: A New Strategy to Target the Malaria Parasite Plasmodium falciparum

por Müller, Ingrid B., Wu, Fang, Bergmann, Bärbel, Knöckel, Julia, Walter, Rolf D., Gehring, Heinz, Wrenger, Carsten
Publicado 2009

Stable Translocation Intermediates Jam Global Protein Export in Plasmodium falciparum Parasites and Link the PTEX Component EXP2 with Translocation Activity

por Mesén-Ramírez, Paolo, Reinsch, Ferdinand, Blancke Soares, Alexandra, Bergmann, Bärbel, Ullrich, Ann-Katrin, Tenzer, Stefan, Spielmann, Tobias
Publicado 2016

Substrate-analogous inhibitors exert antimalarial action by targeting the Plasmodium lactate transporter PfFNT at nanomolar scale

por Golldack, André, Henke, Björn, Bergmann, Bärbel, Wiechert, Marie, Erler, Holger, Blancke Soares, Alexandra, Spielmann, Tobias, Beitz, Eric
Publicado 2017

The Plasmodium Lactate/H(+) Transporter PfFNT Is Essential and Druggable In Vivo

por Davies, Heledd, Bergmann, Bärbel, Walloch, Philipp, Nerlich, Cornelius, Hansen, Christian, Wittlin, Sergio, Spielmann, Tobias, Treeck, Moritz, Beitz, Eric
Publicado 2023

The Vitamin B1 Metabolism of Staphylococcus aureus Is Controlled at Enzymatic and Transcriptional Levels

por Müller, Ingrid B., Bergmann, Bärbel, Groves, Matthew R., Couto, Isabel, Amaral, Leonard, Begley, Tadhg P., Walter, Rolf D., Wrenger, Carsten
Publicado 2009

EXP1 is critical for nutrient uptake across the parasitophorous vacuole membrane of malaria parasites

por Mesén-Ramírez, Paolo, Bergmann, Bärbel, Tran, Thuy Tuyen, Garten, Matthias, Stäcker, Jan, Naranjo-Prado, Isabel, Höhn, Katharina, Zimmerberg, Joshua, Spielmann, Tobias
Publicado 2019