A single-nuclei RNA sequencing study of Mendelian and sporadic AD in the human brain

por Del-Aguila, Jorge L., Li, Zeran, Dube, Umber, Mihindukulasuriya, Kathie A., Budde, John P., Fernandez, Maria Victoria, Ibanez, Laura, Bradley, Joseph, Wang, Fengxian, Bergmann, Kristy, Davenport, Richard, Morris, John C., Holtzman, David M., Perrin, Richard J., Benitez, Bruno A., Dougherty, Joseph, Cruchaga, Carlos, Harari, Oscar
Publicado 2019

Circular RNA detection identifies circPSEN1 alterations in brain specific to autosomal dominant Alzheimer's disease

por Chen, Hsiang-Han, Eteleeb, Abdallah, Wang, Ciyang, Fernandez, Maria Victoria, Budde, John P., Bergmann, Kristy, Norton, Joanne, Wang, Fengxian, Ebl, Curtis, Morris, John C., Perrin, Richard J., Bateman, Randall J., McDade, Eric, Xiong, Chengjie, Goate, Alison, Farlow, Martin, Chhatwal, Jasmeer, Schofield, Peter R., Chui, Helena, Harari, Oscar, Cruchaga, Carlos, Ibanez, Laura
Publicado 2022

Single-nucleus RNA-sequencing of autosomal dominant Alzheimer disease and risk variant carriers

por Brase, Logan, You, Shih-Feng, D’Oliveira Albanus, Ricardo, Del-Aguila, Jorge L., Dai, Yaoyi, Novotny, Brenna C., Soriano-Tarraga, Carolina, Dykstra, Taitea, Fernandez, Maria Victoria, Budde, John P., Bergmann, Kristy, Morris, John C., Bateman, Randall J., Perrin, Richard J., McDade, Eric, Xiong, Chengjie, Goate, Alison M., Farlow, Martin, Sutherland, Greg T., Kipnis, Jonathan, Karch, Celeste M., Benitez, Bruno A., Harari, Oscar
Publicado 2023

Functional genomic analyses uncover APOE-mediated regulation of brain and cerebrospinal fluid beta-amyloid levels in Parkinson disease

por Ibanez, Laura, Bahena, Jorge A., Yang, Chengran, Dube, Umber, Farias, Fabiana H. G., Budde, John P., Bergmann, Kristy, Brenner-Webster, Carol, Morris, John C., Perrin, Richard J., Cairns, Nigel J., O’Donnell, John, Álvarez, Ignacio, Diez-Fairen, Monica, Aguilar, Miquel, Miller, Rebecca, Davis, Albert A., Pastor, Pau, Kotzbauer, Paul, Campbell, Meghan C., Perlmutter, Joel S., Rhinn, Herve, Harari, Oscar, Cruchaga, Carlos, Benitez, Bruno A.
Publicado 2020

Metabolomic and lipidomic signatures in autosomal dominant and late-onset Alzheimer’s disease brains

por Novotny, Brenna C., Fernandez, Maria Victoria, Wang, Ciyang, Budde, John P., Bergmann, Kristy, Eteleeb, Abdallah M., Bradley, Joseph, Webster, Carol, Ebl, Curtis, Norton, Joanne, Gentsch, Jen, Dube, Umber, Wang, Fengxian, Morris, John C., Bateman, Randall J., Perrin, Richard J., McDade, Eric, Xiong, Chengjie, Chhatwal, Jasmeer, Goate, Alison, Farlow, Martin, Schofield, Peter, Chui, Helena, Karch, Celeste M., Cruchaga, Carlos, Benitez, Bruno A., Harari, Oscar
Publicado 2023

MULTI-ANCESTRY GENETIC STUDY IN 5,876 PATIENTS IDENTIFIES AN ASSOCIATION BETWEEN EXCITOTOXIC GENES AND EARLY OUTCOMES AFTER ACUTE ISCHEMIC STROKE.

por Ibanez, Laura, Heitsch, Laura, Carrera, Caty, Farias, Fabiana H.G., Dhar, Rajat, Budde, John, Bergmann, Kristy, Bradley, Joseph, Harari, Oscar, Phuah, Chia-Ling, Lemmens, Robin, Souza, Alessandro A. Viana Oliveira, Moniche, Francisco, Cabezas-Juan, Antonio, Arenillas, Juan Francisco, Krupinksi, Jerzy, Cullell, Natalia, Torres-Aguila, Nuria, Muiño, Elena, Cárcel-Márquez, Jara, Marti-Fabregas, Joan, Delgado-Mederos, Raquel, Marin-Bueno, Rebeca, Hornick, Alejandro, Vives-Bauza, Cristofol, Navarro, Rosa Diaz, Tur, Silvia, Jimenez, Carmen, Obach, Victor, Segura, Tomas, Serrano-Heras, Gemma, Chung, Jong-Won, Roquer, Jaume, Soriano-Tarraga, Carol, Giralt-Steinhauer, Eva, Mola-Caminal, Marina, Pera, Joanna, Lapicka-Bodzioch, Katarzyna, Derbisz, Justyna, Davalos, Antoni, Lopez-Cancio, Elena, Muñoz, Lucia, Tatlisumak, Turgut, Molina, Carlos, Ribo, Marc, Bustamante, Alejandro, Sobrino, Tomas, Castillo-Sanchez, Jose, Campos, Francisco, Rodriguez-Castro, Emilio, Arias-Rivas, Susana, Rodríguez-Yáñez, Manuel, Herbosa, Christina, Ford, Andria L., Arauz, Antonio, Lopes-Cendes, Iscia, Lowenkopf, Theodore, Barboza, Miguel A., Amini, Hajar, Stamova, Boryana, Ander, Bradley P., Sharp, Frank R, Kim, Gyeong Moon, Bang, Oh Young, Jimenez-Conde, Jordi, Slowik, Agnieszka, Stribian, Daniel, Tsai, Ellen A., Burkly, Linda C., Montaner, Joan, Fernandez-Cadenas, Israel, Lee, Jin-Moo, Cruchaga, Carlos
Publicado 2020