Multiple pathways of toxicity induced by C9orf72 dipeptide repeat aggregates and G(4)C(2) RNA in a cellular model

por Frottin, Frédéric, Pérez-Berlanga, Manuela, Hartl, F Ulrich, Hipp, Mark S
Publicado 2021

Establishment of a Structure–Activity Relationship of 1H-Imidazo[4,5-c]quinoline-Based Kinase Inhibitor NVP-BEZ235 as a Lead for African Sleeping Sickness

por Seixas, João D., Luengo-Arratta, Sandra A., Diaz, Rosario, Saldivia, Manuel, Rojas-Barros, Domingo I., Manzano, Pilar, Gonzalez, Silvia, Berlanga, Manuela, Smith, Terry K., Navarro, Miguel, Pollastri, Michael P.
Publicado 2014

Synaptic FUS accumulation triggers early misregulation of synaptic RNAs in a mouse model of ALS

por Sahadevan, Sonu, Hembach, Katharina M., Tantardini, Elena, Pérez-Berlanga, Manuela, Hruska-Plochan, Marian, Megat, Salim, Weber, Julien, Schwarz, Petra, Dupuis, Luc, Robinson, Mark D., De Rossi, Pierre, Polymenidou, Magdalini
Publicado 2021

Identification of “Preferred” Human Kinase Inhibitors for Sleeping Sickness Lead Discovery. Are Some Kinases Better than Others for Inhibitor Repurposing?

por Amata, Emanuele, Xi, Hualin, Colmenarejo, Gonzalo, Gonzalez-Diaz, Rosario, Cordon-Obras, Carlos, Berlanga, Manuela, Manzano, Pilar, Erath, Jessey, Roncal, Norma E., Lee, Patricia J., Leed, Susan E., Rodriguez, Ana, Sciotti, Richard J., Navarro, Miguel, Pollastri, Michael P.
Publicado 2016

Identification and Characterization of Hundreds of Potent and Selective Inhibitors of Trypanosoma brucei Growth from a Kinase-Targeted Library Screening Campaign

por Diaz, Rosario, Luengo-Arratta, Sandra A., Seixas, João D., Amata, Emanuele, Devine, William, Cordon-Obras, Carlos, Rojas-Barros, Domingo I., Jimenez, Elena, Ortega, Fatima, Crouch, Sabrinia, Colmenarejo, Gonzalo, Fiandor, Jose Maria, Martin, Jose Julio, Berlanga, Manuela, Gonzalez, Silvia, Manzano, Pilar, Navarro, Miguel, Pollastri, Michael P.
Publicado 2014

Loss of TDP‐43 oligomerization or RNA binding elicits distinct aggregation patterns

por Pérez‐Berlanga, Manuela, Wiersma, Vera I, Zbinden, Aurélie, De Vos, Laura, Wagner, Ulrich, Foglieni, Chiara, Mallona, Izaskun, Betz, Katharina M, Cléry, Antoine, Weber, Julien, Guo, Zhongning, Rigort, Ruben, de Rossi, Pierre, Manglunia, Ruchi, Tantardini, Elena, Sahadevan, Sonu, Stach, Oliver, Hruska‐Plochan, Marian, Allain, Frederic H‐T, Paganetti, Paolo, Polymenidou, Magdalini
Publicado 2023

FTLD‐TDP assemblies seed neoaggregates with subtype‐specific features via a prion‐like cascade

por De Rossi, Pierre, Lewis, Amanda J, Furrer, Johanna, De Vos, Laura, Demeter, Tomas, Zbinden, Aurélie, Zhong, Weijia, Wiersma, Vera I, Scialo, Carlo, Weber, Julien, Guo, Zhongning, Scaramuzza, Stefano, Di Fabrizio, Marta, Böing, Carolin, Castaño‐Díez, Daniel, Al‐Amoudi, Ashraf, Pérez‐Berlanga, Manuela, Lashley, Tammaryn, Stahlberg, Henning, Polymenidou, Magdalini
Publicado 2021

Comprehensive evaluation of human-derived anti-poly-GA antibodies in cellular and animal models of C9orf72 disease

por Jambeau, Melanie, Meyer, Kevin D., Hruska-Plochan, Marian, Tabet, Ricardos, Lee, Chao-Zong, Ray-Soni, Ananya, Aguilar, Corey, Savage, Kitty, Mishra, Nibha, Cavegn, Nicole, Borter, Petra, Lin, Chun-Chia, Jansen-West, Karen R., Jiang, Jie, Freyermuth, Fernande, Li, Nan, De Rossi, Pierre, Pérez-Berlanga, Manuela, Jiang, Xin, Daughrity, Lilian M., Pereira, João, Narayanan, Sarav, Gu, Yuanzheng, Dhokai, Shekhar, Dalkilic-Liddle, Isin, Maniecka, Zuzanna, Weber, Julien, Workman, Michael, McAlonis-Downes, Melissa, Berezovski, Eugene, Zhang, Yong-Jie, Berry, James, Wainger, Brian J., Kankel, Mark W., Rushe, Mia, Hock, Christoph, Nitsch, Roger M., Cleveland, Don W., Petrucelli, Leonard, Gendron, Tania F., Montrasio, Fabio, Grimm, Jan, Polymenidou, Magdalini, Lagier-Tourenne, Clotilde
Publicado 2022