Akt inhibition improves irinotecan treatment and prevents cell emergence by switching the senescence response to apoptosis

por Vétillard, Alexandra, Jonchère, Barbara, Moreau, Marie, Toutain, Bertrand, Henry, Cécile, Fontanel, Simon, Bernard, Anne-Charlotte, Campone, Mario, Guette, Catherine, Coqueret, Olivier
Publicado 2015

Irinotecan treatment and senescence failure promote the emergence of more transformed and invasive cells that depend on anti-apoptotic Mcl-1

por Jonchère, Barbara, Vétillard, Alexandra, Toutain, Bertrand, Lam, David, Bernard, Anne Charlotte, Henry, Cécile, Trécesson, Sophie De Carné, Gamelin, Erick, Juin, Philippe, Guette, Catherine, Coqueret, Olivier
Publicado 2014

BCL-X(L) directly modulates RAS signalling to favour cancer cell stemness

por Carné Trécesson, Sophie de, Souazé, Frédérique, Basseville, Agnès, Bernard, Anne-Charlotte, Pécot, Jessie, Lopez, Jonathan, Bessou, Margaux, Sarosiek, Kristopher A., Letai, Anthony, Barillé-Nion, Sophie, Valo, Isabelle, Coqueret, Olivier, Guette, Catherine, Campone, Mario, Gautier, Fabien, Juin, Philippe Paul
Publicado 2017