Engineered RBCs Encapsulating Antigen Induce Multi-Modal Antigen-Specific Tolerance and Protect Against Type 1 Diabetes

por Raposo, Colin J., Cserny, Judith D., Serena, Gloria, Chow, Jonathan N., Cho, Patricia, Liu, Hanyang, Kotler, David, Sharei, Armon, Bernstein, Howard, John, Shinu
Publicado 2022

Cell engineering with microfluidic squeezing preserves functionality of primary immune cells in vivo

por DiTommaso, Tia, Cole, Julie M., Cassereau, Luke, Buggé, Joshua A., Hanson, Jacquelyn L. Sikora, Bridgen, Devin T., Stokes, Brittany D., Loughhead, Scott M., Beutel, Bruce A., Gilbert, Jonathan B., Nussbaum, Kathrin, Sorrentino, Antonio, Toggweiler, Janine, Schmidt, Tobias, Gyuelveszi, Gabor, Bernstein, Howard, Sharei, Armon
Publicado 2018

Phase 1 study to determine the safety and dosing of autologous PBMCs modified to present HPV16 antigens (SQZ-PBMC-HPV) in HLA-A*02+ patients with HPV16+ solid tumors

por Jimeno, Antonio, Baranda, Joaquina, Iams, Wade T., Park, Jong Chul, Mita, Monica, Gordon, Michael S., Taylor, Matthew, Dhani, Neesha, Leal, Alexis D., Neupane, Prakash, Eng, Cathy, Yeku, Oladapo, Mita, Alain, Moser, Justin C., Butler, Marcus, Loughhead, Scott M., Jennings, Julia, Miselis, Nathan R., Ji, Rui-Ru, Nair, Nitya, Kornacker, Martin, Zwirtes, Ricardo F., Bernstein, Howard, Sharei, Armon
Publicado 2023

Engineered red blood cells (activating antigen carriers) drive potent T cell responses and tumor regression in mice

por Blagovic, Katarina, Smith, Carolyne K., Ramakrishnan, Amritha, Moore, Lindsay, Soto, David R., Thompson, Zachary, Stockmann, Adam P., Kruszelnicki, Sonia, Thakkar, Akshi, Murray, Jason, Torres, Sebastian, Wondimagegnhu, Bersabel, Yi, Roslyn, Dadgar, Maisam, Paracha, Abdul M., Page, Claire, Clear, Louise, Chaudhry, Omer A., Myint, Melissa, Bridgen, Devin T., Gilbert, Jonathan B., Seidl, Katherine J., Sharei, Armon, Loughhead, Scott, Bernstein, Howard, Yarar, Defne
Publicado 2022