Targeted Disruption of E6/p53 Binding Exerts Broad Activity and Synergism with Paclitaxel and Topotecan against HPV-Transformed Cancer Cells

por Celegato, Marta, Messa, Lorenzo, Bertagnin, Chiara, Mercorelli, Beatrice, Loregian, Arianna
Publicado 2021

A quantitative LumiFluo assay to test inhibitory compounds blocking p53 degradation induced by human papillomavirus oncoprotein E6 in living cells

por Messa, Lorenzo, Celegato, Marta, Bertagnin, Chiara, Mercorelli, Beatrice, Nannetti, Giulio, Palù, Giorgio, Loregian, Arianna
Publicado 2018

The Dimeric Form of HPV16 E6 Is Crucial to Drive YAP/TAZ Upregulation through the Targeting of hScrib

por Messa, Lorenzo, Celegato, Marta, Bertagnin, Chiara, Mercorelli, Beatrice, Alvisi, Gualtiero, Banks, Lawrence, Palù, Giorgio, Loregian, Arianna
Publicado 2021

A novel N-heterocycles substituted oseltamivir derivatives as potent inhibitors of influenza virus neuraminidase: discovery, synthesis and biological evaluation

por Zhang, Jiwei, Liu, Chuanfeng, Jia, Ruifang, Zhang, Xujie, Zhang, Jian, Bertagnin, Chiara, Bonomini, Anna, Guizzo, Laura, Jiang, Yuanmin, Jia, Huinan, Jia, Shuzhen, Ma, Xiuli, Loregian, Arianna, Huang, Bing, Zhan, Peng, Liu, Xinyong
Publicado 2023

Discovery of Novel Boron-Containing N-Substituted Oseltamivir Derivatives as Anti-Influenza A Virus Agents for Overcoming N1-H274Y Oseltamivir-Resistant

por Jia, Ruifang, Zhang, Jiwei, Zhang, Jian, Bertagnin, Chiara, Bonomini, Anna, Guizzo, Laura, Gao, Zhen, Ji, Xiangkai, Li, Zhuo, Liu, Chuanfeng, Ju, Han, Ma, Xiuli, Loregian, Arianna, Huang, Bing, Zhan, Peng, Liu, Xinyong
Publicado 2022

Synthesis and characterization of 1,2,4-triazolo[1,5-a]pyrimidine-2-carboxamide-based compounds targeting the PA-PB1 interface of influenza A virus polymerase

por Massari, Serena, Bertagnin, Chiara, Pismataro, Maria Chiara, Donnadio, Anna, Nannetti, Giulio, Felicetti, Tommaso, Di Bona, Stefano, Nizi, Maria Giulia, Tensi, Leonardo, Manfroni, Giuseppe, Loza, Maria Isabel, Sabatini, Stefano, Cecchetti, Violetta, Brea, Jose, Goracci, Laura, Loregian, Arianna, Tabarrini, Oriana
Publicado 2021