RNA Biogenesis Instructs Functional Inter-Chromosomal Genome Architecture

por Bertero, Alessandro
Publicado 2021

Systematic identification of inter-chromosomal interaction networks supports the existence of RNA factories

por Hristov, Borislav Hrisimirov, Noble, William Stafford, Bertero, Alessandro
Publicado 2023

Initiation of stem cell differentiation involves cell cycle-dependent regulation of developmental genes by Cyclin D

por Pauklin, Siim, Madrigal, Pedro, Bertero, Alessandro, Vallier, Ludovic
Publicado 2016

Inducible and Deterministic Forward Programming of Human Pluripotent Stem Cells into Neurons, Skeletal Myocytes, and Oligodendrocytes

por Pawlowski, Matthias, Ortmann, Daniel, Bertero, Alessandro, Tavares, Joana M., Pedersen, Roger A., Vallier, Ludovic, Kotter, Mark R.N.
Publicado 2017

Dynamics of genome reorganization during human cardiogenesis reveal an RBM20-dependent splicing factory

por Bertero, Alessandro, Fields, Paul A., Ramani, Vijay, Bonora, Giancarlo, Yardimci, Galip G., Reinecke, Hans, Pabon, Lil, Noble, William S., Shendure, Jay, Murry, Charles E.
Publicado 2019

Activin/Nodal signaling and NANOG orchestrate human embryonic stem cell fate decisions by controlling the H3K4me3 chromatin mark

por Bertero, Alessandro, Madrigal, Pedro, Galli, Antonella, Hubner, Nina C., Moreno, Inmaculada, Burks, Deborah, Brown, Stephanie, Pedersen, Roger A., Gaffney, Daniel, Mendjan, Sasha, Pauklin, Siim, Vallier, Ludovic
Publicado 2015

Dynamic chromatin organization and regulatory interactions in human endothelial cell differentiation

por Alavattam, Kris G., Mitzelfelt, Katie A., Bonora, Giancarlo, Fields, Paul A., Yang, Xiulan, Chiu, Han Sheng, Pabon, Lil, Bertero, Alessandro, Palpant, Nathan J., Noble, William S., Murry, Charles E.
Publicado 2022

Epicardially secreted fibronectin drives cardiomyocyte maturation in 3D-engineered heart tissues

por Ong, Lay Ping, Bargehr, Johannes, Knight-Schrijver, Vincent R., Lee, Jonathan, Colzani, Maria, Bayraktar, Semih, Bernard, William G., Marchiano, Silvia, Bertero, Alessandro, Murry, Charles E., Gambardella, Laure, Sinha, Sanjay
Publicado 2023

Chromatin compartment dynamics in a haploinsufficient model of cardiac laminopathy

por Bertero, Alessandro, Fields, Paul A., Smith, Alec S.T., Leonard, Andrea, Beussman, Kevin, Sniadecki, Nathan J., Kim, Deok-Ho, Tse, Hung-Fat, Pabon, Lil, Shendure, Jay, Noble, William S., Murry, Charles E.
Publicado 2019

Early anteroposterior regionalisation of human neural crest is shaped by a pro-mesodermal factor

por Gogolou, Antigoni, Souilhol, Celine, Granata, Ilaria, Wymeersch, Filip J, Manipur, Ichcha, Wind, Matthew, Frith, Thomas JR, Guarini, Maria, Bertero, Alessandro, Bock, Christoph, Halbritter, Florian, Takasato, Minoru, Guarracino, Mario R, Tsakiridis, Anestis
Publicado 2022

The K219T-Lamin mutation induces conduction defects through epigenetic inhibition of SCN5A in human cardiac laminopathy

por Salvarani, Nicolò, Crasto, Silvia, Miragoli, Michele, Bertero, Alessandro, Paulis, Marianna, Kunderfranco, Paolo, Serio, Simone, Forni, Alberto, Lucarelli, Carla, Dal Ferro, Matteo, Larcher, Veronica, Sinagra, Gianfranco, Vezzoni, Paolo, Murry, Charles E., Faggian, Giuseppe, Condorelli, Gianluigi, Di Pasquale, Elisa
Publicado 2019

The SMAD2/3 interactome reveals that TGFβ controls m(6)A mRNA methylation in pluripotency

por Bertero, Alessandro, Brown, Stephanie, Madrigal, Pedro, Osnato, Anna, Ortmann, Daniel, Yiangou, Loukia, Kadiwala, Juned, Hubner, Nina C., de los Mozos, Igor Ruiz, Sadee, Christoph, Lenaerts, An-Sofie, Nakanoh, Shota, Grandy, Rodrigo, Farnell, Edward, Ule, Jernej, Stunnenberg, Hendrik G., Mendjan, Sasha, Vallier, Ludovic
Publicado 2018

Cholangiocytes derived from human induced pluripotent stem cells for disease modeling and drug validation

por Sampaziotis, Fotios, de Brito, Miguel Cardoso, Madrigal, Pedro, Bertero, Alessandro, Saeb-Parsy, Kourosh, Soares, Filipa A. C., Schrumpf, Elisabeth, Melum, Espen, Karlsen, Tom H., Bradley, J. Andrew, Gelson, William TH, Davies, Susan, Baker, Alastair, Kaser, Arthur, Alexander, Graeme J., Hannan, Nicholas R.F., Vallier, Ludovic
Publicado 2015

Epicardial cells derived from human embryonic stem cells augment cardiomyocyte-driven heart regeneration

por Bargehr, Johannes, Ong, Lay Ping, Colzani, Maria, Davaapil, Hongorzul, Hofsteen, Peter, Bhandari, Shiv, Gambardella, Laure, Novère, Nicolas Le, Iyer, Dharini, Sampaziotis, Fotios, Weinberger, Florian, Bertero, Alessandro, Leonard, Andrea, Bernard, William G, Martinson, Amy, Figg, Nichola, Regnier, Michael, Bennett, Martin R, Murry, Charles E, Sinha, Sanjay
Publicado 2019

SARS-CoV-2 Infects Human Pluripotent Stem Cell-Derived Cardiomyocytes, Impairing Electrical and Mechanical Function

por Marchiano, Silvia, Hsiang, Tien-Ying, Khanna, Akshita, Higashi, Ty, Whitmore, Leanne S., Bargehr, Johannes, Davaapil, Hongorzul, Chang, Jean, Smith, Elise, Ong, Lay Ping, Colzani, Maria, Reinecke, Hans, Yang, Xiulan, Pabon, Lil, Sinha, Sanjay, Najafian, Behzad, Sniadecki, Nathan J., Bertero, Alessandro, Gale, Michael, Murry, Charles E.
Publicado 2021

Optimized inducible shRNA and CRISPR/Cas9 platforms for in vitro studies of human development using hPSCs

por Bertero, Alessandro, Pawlowski, Matthias, Ortmann, Daniel, Snijders, Kirsten, Yiangou, Loukia, Cardoso de Brito, Miguel, Brown, Stephanie, Bernard, William G., Cooper, James D., Giacomelli, Elisa, Gambardella, Laure, Hannan, Nicholas R. F., Iyer, Dharini, Sampaziotis, Fotios, Serrano, Felipe, Zonneveld, Mariëlle C. F., Sinha, Sanjay, Kotter, Mark, Vallier, Ludovic
Publicado 2016

Genome editing reveals a role for OCT4 in human embryogenesis

por Fogarty, Norah M. E., McCarthy, Afshan, Snijders, Kirsten E., Powell, Benjamin E., Kubikova, Nada, Blakeley, Paul, Lea, Rebecca, Elder, Kay, Wamaitha, Sissy E., Kim, Daesik, Maciulyte, Valdone, Kleinjung, Jens, Kim, Jin-Soo, Wells, Dagan, Vallier, Ludovic, Bertero, Alessandro, Turner, James M. A., Niakan, Kathy K.
Publicado 2017

Pharmacologic therapy for engraftment arrhythmia induced by transplantation of human cardiomyocytes

por Nakamura, Kenta, Neidig, Lauren E., Yang, Xiulan, Weber, Gerhard J., El-Nachef, Danny, Tsuchida, Hiroshi, Dupras, Sarah, Kalucki, Faith A., Jayabalu, Anu, Futakuchi-Tsuchida, Akiko, Nakamura, Daisy S., Marchianò, Silvia, Bertero, Alessandro, Robinson, Melissa R., Cain, Kevin, Whittington, Dale, Tian, Rong, Reinecke, Hans, Pabon, Lil, Knollmann, Björn C., Kattman, Steven, Thies, R. Scott, MacLellan, W. Robb, Murry, Charles E.
Publicado 2021

Gain-of-function cardiomyopathic mutations in RBM20 rewire splicing regulation and re-distribute ribonucleoprotein granules within processing bodies

por Fenix, Aidan M., Miyaoka, Yuichiro, Bertero, Alessandro, Blue, Steven M., Spindler, Matthew J., Tan, Kenneth K. B., Perez-Bermejo, Juan A., Chan, Amanda H., Mayerl, Steven J., Nguyen, Trieu D., Russell, Caitlin R., Lizarraga, Paweena P., Truong, Annie, So, Po-Lin, Kulkarni, Aishwarya, Chetal, Kashish, Sathe, Shashank, Sniadecki, Nathan J., Yeo, Gene W., Murry, Charles E., Conklin, Bruce R., Salomonis, Nathan
Publicado 2021