Inferring Reasons for the Failure of Staphylococcus aureus Vaccines in Clinical Trials

por Bagnoli, Fabio, Bertholet, Sylvie, Grandi, Guido
Publicado 2012

Novel Platforms for the Development of a Universal Influenza Vaccine

por Kumar, Arun, Meldgaard, Trine Sundebo, Bertholet, Sylvie
Publicado 2018

Technological approaches to streamline vaccination schedules, progressing towards single-dose vaccines

por Lofano, Giuseppe, Mallett, Corey P., Bertholet, Sylvie, O’Hagan, Derek T.
Publicado 2020

B Cells and Functional Antibody Responses to Combat Influenza

por Lofano, Giuseppe, Kumar, Arun, Finco, Oretta, Del Giudice, Giuseppe, Bertholet, Sylvie
Publicado 2015

Single-Cell Analysis of Antigen-Specific CD8+ T-Cell Transcripts Reveals Profiles Specific to mRNA or Adjuvanted Protein Vaccines

por Meldgaard, Trine Sundebo, Blengio, Fabiola, Maffione, Denise, Sammicheli, Chiara, Tavarini, Simona, Nuti, Sandra, Kratzer, Roland, Medini, Duccio, Siena, Emilio, Bertholet, Sylvie
Publicado 2021

Innate Response Activator (IRA) B Cells Reside in Human Tonsils and Internalize Bacteria In Vitro

por Chiappini, Nico, Cantisani, Rocco, Pancotto, Laura, Ruggiero, Paolo, Rosa, Domenico, Manetti, Andrea, Romano, Antonio, Montagnani, Francesca, Bertholet, Sylvie, Castellino, Flora, Del Giudice, Giuseppe
Publicado 2015

Self-Amplifying mRNA Vaccines Expressing Multiple Conserved Influenza Antigens Confer Protection against Homologous and Heterosubtypic Viral Challenge

por Magini, Diletta, Giovani, Cinzia, Mangiavacchi, Simona, Maccari, Silvia, Cecchi, Raffaella, Ulmer, Jeffrey B., De Gregorio, Ennio, Geall, Andrew J., Brazzoli, Michela, Bertholet, Sylvie
Publicado 2016

An Innovative Pseudotypes-Based Enzyme-Linked Lectin Assay for the Measurement of Functional Anti-Neuraminidase Antibodies

por Prevato, Marua, Cozzi, Roberta, Pezzicoli, Alfredo, Taddei, Anna Rita, Ferlenghi, Ilaria, Nandi, Avishek, Montomoli, Emanuele, Settembre, Ethan C., Bertholet, Sylvie, Bonci, Alessandra, Legay, Francois
Publicado 2015

Expression and Characterization of Recombinant, Tetrameric and Enzymatically Active Influenza Neuraminidase for the Setup of an Enzyme-Linked Lectin-Based Assay

por Prevato, Marua, Ferlenghi, Ilaria, Bonci, Alessandra, Uematsu, Yasushi, Anselmi, Giulia, Giusti, Fabiola, Bertholet, Sylvie, Legay, Francois, Telford, John Laird, Settembre, Ethan C., Maione, Domenico, Cozzi, Roberta
Publicado 2015

Development and Characterization of Synthetic Glucopyranosyl Lipid Adjuvant System as a Vaccine Adjuvant

por Coler, Rhea N., Bertholet, Sylvie, Moutaftsi, Magdalini, Guderian, Jeff A., Windish, Hillarie Plessner, Baldwin, Susan L., Laughlin, Elsa M., Duthie, Malcolm S., Fox, Christopher B., Carter, Darrick, Friede, Martin, Vedvick, Thomas S., Reed, Steven G.
Publicado 2011

Early Rise of Blood T Follicular Helper Cell Subsets and Baseline Immunity as Predictors of Persisting Late Functional Antibody Responses to Vaccination in Humans

por Spensieri, Fabiana, Siena, Emilio, Borgogni, Erica, Zedda, Luisanna, Cantisani, Rocco, Chiappini, Nico, Schiavetti, Francesca, Rosa, Domenico, Castellino, Flora, Montomoli, Emanuele, Bodinham, Caroline L., Lewis, David J., Medini, Duccio, Bertholet, Sylvie, Del Giudice, Giuseppe
Publicado 2016

A Synthetic Adjuvant to Enhance and Expand Immune Responses to Influenza Vaccines

por Coler, Rhea N., Baldwin, Susan L., Shaverdian, Narek, Bertholet, Sylvie, Reed, Steven J., Raman, Vanitha S., Lu, Xiuhua, DeVos, Joshua, Hancock, Kathy, Katz, Jacqueline M., Vedvick, Thomas S., Duthie, Malcolm S., Clegg, Christopher H., Van Hoeven, Neal, Reed, Steven G.
Publicado 2010

Staphylococcus aureus-dependent septic arthritis in murine knee joints: local immune response and beneficial effects of vaccination

por Corrado, Alessia, Donato, Paolo, Maccari, Silvia, Cecchi, Raffaella, Spadafina, Tiziana, Arcidiacono, Letizia, Tavarini, Simona, Sammicheli, Chiara, Laera, Donatello, Manetti, Andrea Guido Oreste, Ruggiero, Paolo, Galletti, Bruno, Nuti, Sandra, De Gregorio, Ennio, Bertholet, Sylvie, Seubert, Anja, Bagnoli, Fabio, Bensi, Giuliano, Chiarot, Emiliano
Publicado 2016

MF59- and Al(OH)(3)-Adjuvanted Staphylococcus aureus (4C-Staph) Vaccines Induce Sustained Protective Humoral and Cellular Immune Responses, with a Critical Role for Effector CD4 T...

por Monaci, Elisabetta, Mancini, Francesca, Lofano, Giuseppe, Bacconi, Marta, Tavarini, Simona, Sammicheli, Chiara, Arcidiacono, Letizia, Giraldi, Monica, Galletti, Bruno, Rossi Paccani, Silvia, Torre, Antonina, Fontana, Maria Rita, Grandi, Guido, de Gregorio, Ennio, Bensi, Giuliano, Chiarot, Emiliano, Nuti, Sandra, Bagnoli, Fabio, Soldaini, Elisabetta, Bertholet, Sylvie
Publicado 2015

One Dose of Staphylococcus aureus 4C-Staph Vaccine Formulated with a Novel TLR7-Dependent Adjuvant Rapidly Protects Mice through Antibodies, Effector CD4(+) T Cells, and IL-17A

por Mancini, Francesca, Monaci, Elisabetta, Lofano, Giuseppe, Torre, Antonina, Bacconi, Marta, Tavarini, Simona, Sammicheli, Chiara, Arcidiacono, Letizia, Galletti, Bruno, Laera, Donatello, Pallaoro, Michele, Tuscano, Giovanna, Fontana, Maria Rita, Bensi, Giuliano, Grandi, Guido, Rossi-Paccani, Silvia, Nuti, Sandra, Rappuoli, Rino, De Gregorio, Ennio, Bagnoli, Fabio, Soldaini, Elisabetta, Bertholet, Sylvie
Publicado 2016

A phase I, randomized, controlled, dose-ranging study of investigational acellular pertussis (aP) and reduced tetanus-diphtheria-acellular pertussis (TdaP) booster vaccines in adul...

por Leroux-Roels, Geert, Lattanzi, Maria, Solis, Claudia Dovali, Contorni, Mario, Costantini, Marco, Moraschini, Luca, Bardelli, Monia, Bertholet, Sylvie, Borgogni, Erica, Buricchi, Francesca, Cantisani, Rocco, Faenzi, Elisa, Finco, Oretta, Leuzzi, Rosanna, Pizza, Mariagrazia, Rosa, Domenico, Schiavetti, Francesca, Seubert, Anja, Spensieri, Fabiana, Volpini, Gianfranco, Zedda, Luisanna, Giudice, Giuseppe Del, Galgani, Ilaria
Publicado 2017

MRI/PET multimodal imaging of the innate immune response in skeletal muscle and draining lymph node post vaccination in rats

por Madi, Saaussan, Xie, Fang, Farhangi, Kamyar, Hsu, Chih-Yang, Cheng, Shih-Hsun, Aweda, Tolulope, Radaram, Bhasker, Slania, Stephanie, Lambert, Tammy, Rambo, Mary, Skedzielewski, Tina, Cole, Austin, Sherina, Valeriia, McKearnan, Shannon, Tran, Hoang, Alsaid, Hasan, Doan, Minh, Stokes, Alan H., O’Hagan, Derek T., Maruggi, Giulietta, Bertholet, Sylvie, Temmerman, Stéphane T., Johnson, Russell, Jucker, Beat M.
Publicado 2023

Rapidly produced SAM(®) vaccine against H7N9 influenza is immunogenic in mice

por Hekele, Armin, Bertholet, Sylvie, Archer, Jacob, Gibson, Daniel G, Palladino, Giuseppe, Brito, Luis A, Otten, Gillis R, Brazzoli, Michela, Buccato, Scilla, Bonci, Alessandra, Casini, Daniele, Maione, Domenico, Qi, Zhi-Qing, Gill, John E, Caiazza, Nicky C, Urano, Jun, Hubby, Bolyn, Gao, George F, Shu, Yuelong, De Gregorio, Ennio, Mandl, Christian W, Mason, Peter W, Settembre, Ethan C, Ulmer, Jeffrey B, Craig Venter, J, Dormitzer, Philip R, Rappuoli, Rino, Geall, Andrew J
Publicado 2013

A self-amplifying mRNA SARS-CoV-2 vaccine candidate induces safe and robust protective immunity in preclinical models

por Maruggi, Giulietta, Mallett, Corey P., Westerbeck, Jason W., Chen, Tiffany, Lofano, Giuseppe, Friedrich, Kristian, Qu, Lin, Sun, Jennifer Tong, McAuliffe, Josie, Kanitkar, Amey, Arrildt, Kathryn T., Wang, Kai-Fen, McBee, Ian, McCoy, Deborah, Terry, Rebecca, Rowles, Alison, Abrahim, Maia Araujo, Ringenberg, Michael A., Gains, Malcolm J., Spickler, Catherine, Xie, Xuping, Zou, Jing, Shi, Pei-Yong, Dutt, Taru, Henao-Tamayo, Marcela, Ragan, Izabela, Bowen, Richard A., Johnson, Russell, Nuti, Sandra, Luisi, Kate, Ulmer, Jeffrey B., Steff, Ann-Muriel, Jalah, Rashmi, Bertholet, Sylvie, Stokes, Alan H., Yu, Dong
Publicado 2022