A dual phosphorylation switch controls 14-3-3-dependent cell surface expression of TASK-1

por Kilisch, Markus, Lytovchenko, Olga, Arakel, Eric C., Bertinetti, Daniela, Schwappach, Blanche
Publicado 2016

Crystal structures of the carboxyl cGMP binding domain of plasmodium falciparum cGMP-dependent protein kinase reveals a novel salt bridge crucial for activation

por Kim, Jeong Joo, Figueroa, Eduardo Sanabria, Franz, Eugen, Bertinetti, Daniela, Herberg, Friedrich, Kim, Choel
Publicado 2013

The role of a parasite-specific D-site in activation of Plasmodium falciparum cGMP-dependent protein kinase

por Franz, Eugen, Kim, Jeong Joo, Schneider, Olga, Bertinetti, Daniela, Kim, Choel, Herberg, Friedrich W
Publicado 2015

A novel c-di-GMP binding domain in glycosyltransferase BgsA is responsible for the synthesis of a mixed-linkage β-glucan

por Pérez-Mendoza, Daniel, Bertinetti, Daniela, Lorenz, Robin, Gallegos, María-Trinidad, Herberg, Friedrich W., Sanjuán, Juan
Publicado 2017

S-Adenosyl-L-Homocysteine Hydrolase Inhibition by a Synthetic Nicotinamide Cofactor Biomimetic

por Kailing, Lyn L., Bertinetti, Daniela, Paul, Caroline E., Manszewski, Tomasz, Jaskolski, Mariusz, Herberg, Friedrich W., Pavlidis, Ioannis V.
Publicado 2018

Binding of the Human 14-3-3 Isoforms to Distinct Sites in the Leucine-Rich Repeat Kinase 2

por Manschwetus, Jascha T., Wallbott, Maximilian, Fachinger, Alexandra, Obergruber, Claudia, Pautz, Sabine, Bertinetti, Daniela, Schmidt, Sven H., Herberg, Friedrich W.
Publicado 2020

Capturing the domain crosstalk in full length LRRK2 and LRRK2(RCKW)

por Störmer, Eliza, Weng, Jui-Hung, Wu, Jian, Bertinetti, Daniela, Kaila Sharma, Pallavi, Ma, Wen, Herberg, Friedrich W., Taylor, Susan S.
Publicado 2023

Chemical tools selectively target components of the PKA system

por Bertinetti, Daniela, Schweinsberg, Sonja, Hanke, Susanne E, Schwede, Frank, Bertinetti, Oliver, Drewianka, Stephan, Genieser, Hans-Gottfried, Herberg, Friedrich W
Publicado 2009

The Pseudomonas aeruginosa Chemotaxis Methyltransferase CheR1 Impacts on Bacterial Surface Sampling

por Schmidt, Juliane, Müsken, Mathias, Becker, Tanja, Magnowska, Zofia, Bertinetti, Daniela, Möller, Stefan, Zimmermann, Bastian, Herberg, Friedrich W., Jänsch, Lothar, Häussler, Susanne
Publicado 2011

Molecular Basis for Ser/Thr Specificity in PKA Signaling

por Knape, Matthias J., Wallbott, Maximilian, Burghardt, Nicole C. G., Bertinetti, Daniela, Hornung, Jan, Schmidt, Sven H., Lorenz, Robin, Herberg, Friedrich W.
Publicado 2020

Transforming PKA into PKG – a structure-function approach to understand cyclic nucleotide selectivity

por Lorenz, Robin, Moon, Eui-Whan, Huang, Gilbert Y, Reger, Albert S, Kim, Jeong J, Franz, Eugen, Bertinetti, Daniela, Kim, Choel, Herberg, Friedrich W
Publicado 2013

Crystal Structures of the Carboxyl cGMP Binding Domain of the Plasmodium falciparum cGMP-dependent Protein Kinase Reveal a Novel Capping Triad Crucial for Merozoite Egress

por Kim, Jeong Joo, Flueck, Christian, Franz, Eugen, Sanabria-Figueroa, Eduardo, Thompson, Eloise, Lorenz, Robin, Bertinetti, Daniela, Baker, David A., Herberg, Friedrich W., Kim, Choel
Publicado 2015

New cGMP analogues restrain proliferation and migration of melanoma cells

por Vighi, Eleonora, Rentsch, Andreas, Henning, Philipp, Comitato, Antonella, Hoffmann, Dorit, Bertinetti, Daniela, Bertolotti, Evelina, Schwede, Frank, Herberg, Friedrich W., Genieser, Hans-Gottfried, Marigo, Valeria
Publicado 2017

cAMP-Dependent Signaling Pathways as Potential Targets for Inhibition of Plasmodium falciparum Blood Stages

por Lasonder, Edwin, More, Kunal, Singh, Shailja, Haidar, Malak, Bertinetti, Daniela, Kennedy, Eileen J., Herberg, Friedrich W., Holder, Anthony A., Langsley, Gordon, Chitnis, Chetan E.
Publicado 2021

Isoform-Selective Disruption of AKAP-Localized PKA Using Hydrocarbon Stapled Peptides

por Wang, Yuxiao, Ho, Tienhuei G., Bertinetti, Daniela, Neddermann, Matthias, Franz, Eugen, Mo, Gary C. H., Schendowich, Lewis P., Sukhu, Avinash, Spelts, Raybun C., Zhang, Jin, Herberg, Friedrich W., Kennedy, Eileen J.
Publicado 2014

Correction to Isoform-Selective Disruption of AKAP-Localized PKA Using Hydrocarbon Stapled Peptides

por Wang, Yuxiao, Ho, Tienhuei G., Bertinetti, Daniela, Neddermann, Matthias, Franz, Eugen, Mo, Gary C. H., Schendowich, Lewis P., Sukhu, Avinash, Spelts, Raybun C., Zhang, Jin, Herberg, Friedrich W., Kennedy, Eileen J.
Publicado 2014

Structure-Guided Design of Selective Epac1 and Epac2 Agonists

por Schwede, Frank, Bertinetti, Daniela, Langerijs, Carianne N., Hadders, Michael A., Wienk, Hans, Ellenbroek, Johanne H., de Koning, Eelco J. P., Bos, Johannes L., Herberg, Friedrich W., Genieser, Hans-Gottfried, Janssen, Richard A. J., Rehmann, Holger
Publicado 2015

Structures of human PKG reveal cGMP-selectived activation mechanisms

por Huang, Gilbert Y, Kim, Jeong J, Reger, Albert S, Lorenz, Robin, Moon, Eui-Whan, Zhao, Chi, Casteel, Darren E, Bertinetti, Daniela, VanSchouwen, Bryan, Selvaratnam, Rajeevan, Pflugrath, James W, Sankaran, Banumathi, Melacini, Giuseppe, Herberg, Friedrich W, Kim, Choel
Publicado 2013

Abstracts from the 8th International Conference on cGMP Generators, Effectors and Therapeutic Implications: Bamberg, Germany. 23-25 June, 2017

por Todd Milne, G., Sandner, Peter, Lincoln, Kathleen A., Harrison, Paul C., Chen, Hongxing, Wang, Hong, Clifford, Holly, Qian, Hu Sheng, Wong, Diane, Sarko, Chris, Fryer, Ryan, Richman, Jeremy, Reinhart, Glenn A., Boustany, Carine M., Pullen, Steven S., Andresen, Henriette, Moltzau, Lise Román, Cataliotti, Alessandro, Levy, Finn Olav, Lukowski, Robert, Frankenreiter, Sandra, Friebe, Andreas, Calamaras, Timothy, Baumgartner, Robert, McLaughlin, Angela, Aronovitz, Mark, Baur, Wendy, Wang, Guang-Rong, Kapur, Navin, Karas, Richard, Blanton, Robert, Hell, Stefan, Waldman, Scott A., Lin, Jieru E., Colon-Gonzalez, Francheska, Kim, Gilbert W., Blomain, Erik S., Merlino, Dante, Snook, Adam, Erdmann, Jeanette, Wobst, Jana, Kessler, Thorsten, Schunkert, Heribert, Walter, Ulrich, Pagel, Oliver, Walter, Elena, Gambaryan, Stepan, Smolenski, Albert, Jurk, Kerstin, Zahedi, Rene, Klinger, James R., Benza, Raymond L., Corris, Paul A., Langleben, David, Naeije, Robert, Simonneau, Gérald, Meier, Christian, Colorado, Pablo, Chang, Mi Kyung, Busse, Dennis, Hoeper, Marius M., Masferrer, Jaime L., Jacobson, Sarah, Liu, Guang, Sarno, Renee, Bernier, Sylvie, Zhang, Ping, Todd Milne, G., Flores-Costa, Roger, Currie, Mark, Hall, Katherine, Möhrle, Dorit, Reimann, Katrin, Wolter, Steffen, Wolters, Markus, Mergia, Evanthia, Eichert, Nicole, Geisler, Hyun-Soon, Ruth, Peter, Friebe, Andreas, Feil, Robert, Zimmermann, Ulrike, Koesling, Doris, Knipper, Marlies, Rüttiger, Lukas, Tanaka, Yasutake, Okamoto, Atsuko, Nojiri, Takashi, Kumazoe, Motofumi, Tokudome, Takeshi, Miura, Koichi, Hino, Jun, Hosoda, Hiroshi, Miyazato, Mikiya, Kangawa, Kenji, Kapil, Vikas, Ahluwalia, Amrita, Paolocci, Nazareno, Eaton, Philip, Campbell, James C., Henning, Philipp, Franz, Eugen, Sankaran, Banumathi, Herberg, Friedrich W., Kim, Choel, Wittwer, M., Luo, Q., Kaila, V., Dames, S. A., Tobin, Andrew, Alam, Mahmood, Rudyk, Olena, Krasemann, Susanne, Hartmann, Kristin, Prysyazhna, Oleksandra, Zhang, Min, Zhao, Lan, Weiss, Astrid, Schermuly, Ralph, Eaton, Philip, Moyes, Amie J., Chu, Sandy M., Baliga, Reshma S., Hobbs, Adrian J., Michalakis, Stylianos, Mühlfriedel, Regine, Schön, Christian, Fischer, Dominik M., Wilhelm, Barbara, Zobor, Ditta, Kohl, Susanne, Peters, Tobias, Zrenner, Eberhart, Bartz-Schmidt, Karl Ulrich, Ueffing, Marius, Wissinger, Bernd, Seeliger, Mathias, Biel, Martin, Ranek, Mark J., Kokkonen, Kristen M., Lee, Dong I., Holewinski, Ronald J., Agrawal, Vineet, Virus, Cornelia, Stevens, Donté A., Sasaki, Masayuki, Zhang, Huaqun, Mannion, Mathew M., Rainer, Peter P., Page, Richard C., Schisler, Jonathan C., Van Eyk, Jennifer E., Willis, Monte S., Kass, David A., Zaccolo, Manuela, Russwurm, Michael, Giesen, Jan, Russwurm, Corina, Füchtbauer, Ernst-Martin, Koesling, Doris, Bork, Nadja I., Nikolaev, Viacheslav O., Agulló, Luis, Floor, Martin, Villà-Freixa, Jordi, Manfra, Ornella, Calamera, Gaia, Surdo, Nicoletta C., Meier, Silja, Froese, Alexander, Nikolaev, Viacheslav O., Zaccolo, Manuela, Levy, Finn Olav, Andressen, Kjetil Wessel, Aue, Annemarie, Schwiering, Fabian, Groneberg, Dieter, Friebe, Andreas, Bajraktari, Gzona, Burhenne, Jürgen, Haefeli, Walter E., Weiss, Johanna, Beck, Katharina, Voussen, Barbara, Vincent, Alexander, Parsons, Sean P., Huizinga, Jan D., Friebe, Andreas, Mónica, Fabiola Zakia, Seto, Edward, Murad, Ferid, Bian, Ka, Burgoyne, Joseph R., Prysyazhna, Oleksandra, Richards, Daniel, Eaton, Philip, Calamera, Gaia, Bjørnerem, Marianne, Ulsund, Andrea Hembre, Kim, Jeong Joo, Kim, Choel, Levy, Finn Olav, Andressen, Kjetil Wessel, Donzelli, Sonia, Goetz, Mara, Schmidt, Kjestine, Wolters, Markus, Stathopoulou, Konstantina, Prysyazhna, Oleksandra, Scotcher, Jenna, Dees, Christian, Subramanian, Hariharan, Butt, Elke, Kamynina, Alisa, Bruce King, S., Nikolaev, Viacheslav O., de Witt, Cor, Leichert, Lars I., Feil, Robert, Eaton, Philip, Cuello, Friederike, Dobrowinski, Hyazinth, Lehners, Moritz, Schmidt, Michael Paolillo Hannes, Feil, Robert, Feil, Susanne, Wen, Lai, Wolters, Markus, Thunemann, Martin, Schmidt, Kjestine, Olbrich, Marcus, Langer, Harald, Gawaz, Meinrad, Friebe, Andreas, de Wit, Cor, Feil, Robert, Franz, Eugen, Kim, Jeong Joo, Bertinetti, Daniela, Kim, Choel, Herberg, Friedrich W., Ghofrani, Hossein-Ardeschir, Grimminger, Friedrich, Grünig, Ekkehard, Huang, Yigao, Jansa, Pavel, Jing, Zhi Cheng, Kilpatrick, David, Langleben, David, Rosenkranz, Stephan, Menezes, Flavia, Fritsch, Arno, Nikkho, Sylvia, Frey, Reiner, Humbert, Marc, Groneberg, Dieter, Aue, Annemarie, Schwiering, Fabian, Friebe, Andreas, Harloff, Manuela, Reinders, Joerg, Schlossmann, Jens, Jung, Joon, Wales, Jessica A., Chen, Cheng-Yu, Breci, Linda, Weichsel, Andrzej, Bernier, Sylvie G., Solinga, Robert, Sheppeck, James E., Renhowe, Paul A., Montfort, William R., Qin, Liying, Sung, Ying-Ju, Casteel, Darren, Kim, Choel, Kollau, Alexander, Neubauer, Andrea, Schrammel, Astrid, Russwurm, Michael, Koesling, Doris, Mayer, Bernd, Kumazoe, Motofumi, Takai, Mika, Takeuchi, Chieri, Kadomatsu, Mai, Hiroi, Shun, Takamatsu, Kanako, Nojiri, Takashi, Kangawa, Kenji, Tachibana, Hirofumi, Opelt, Marissa, Eroglu, Emrah, Waldeck-Weiermair, Markus, Russwurm, Michael, Koesling, Doris, Malli, Roland, Graier, Wolfgang F., Fassett, John T., Schrammel, Astrid, Mayer, Bernd, Sollie, Selene J., Moltzau, Lise Román, Hernandez-Valladares, Maria, Berven, Frode, Levy, Finn Olav, Andressen, Kjetil W., Nojiri, Takashi, Tokudome, Takeshi, Kumazoe, Motofumi, Arai, Miki, Suzuki, Yutaka, Miura, Koichi, Hino, Jun, Hosoda, Hiroshi, Miyazato, Mikiya, Okumura, Meinoshin, Kawaoka, Shinpei, Kangawa, Kenji, Peters, Stefanie, Schmidt, Hannes, Selin Kenet, B., Nies, Sarah Helena, Frank, Katharina, Wen, Lai, Rathjen, Fritz G., Feil, Robert, Petrova, Olga N., Lamarre, Isabelle, Négrerie, Michel, Robinson, Jerid W., Egbert, Jeremy R., Davydova, Julia, Jaffe, Laurinda A., Potter, Lincoln R., Robinson, Jerid W., Blixt, Nicholas, Shuhaibar, Leia C., Warren, Gordon L., Mansky, Kim C., Jaffe, Laurinda A., Potter, Lincoln R., Romoli, Simone, Bauch, Tobias, Dröbner, Karoline, Eitner, Frank, Ruppert, Mihály, Radovits, Tamás, Korkmaz-Icöz, Sevil, Li, Shiliang, Hegedűs, Péter, Loganathan, Sivakanan, Németh, Balázs Tamás, Oláh, Attila, Mátyás, Csaba, Benke, Kálmán, Merkely, Béla, Karck, Matthias, Szabó, Gábor, Scheib, Ulrike, Broser, Matthias, Mukherjee, Shatanik, Stehfest, Katja, Gee, Christine E., Körschen, Heinz G., Oertner, Thomas G., Hegemann, Peter, Schmidt, Hannes, Dickey, Deborah M., Dumoulin, Alexandre, Kühn, Ralf, Jaffe, Laurinda, Potter, Lincoln R., Rathjen, Fritz G., Schobesberger, Sophie, Wright, Peter, Poulet, Claire, Mansfield, Catherine, Friebe, Andreas, Harding, Sian E., Nikolaev, Viacheslav O., Gorelik, Julia, Kollau, Alexander, Opelt, Marissa, Wölkart, Gerald, Gorren, Antonius C. F., Russwurm, Michael, Koesling, Doris, Schrammel, Astrid, Mayer, Bernd, Schwaerzer, Gerburg K., Casteel, Darren E., Dalton, Nancy D., Gu, Yusu, Zhuang, Shunhui, Milewicz, Dianna M., Peterson, Kirk L., Pilz, Renate, Schwiering, Fabian, Aue, Annemarie, Groneberg, Dieter, Friebe, Andreas, Argyriou, Aikaterini I., Makrynitsa, Garyfalia, Alexandropoulos, Ioannis I., Stamopoulou, Andriana, Bantzi, Marina, Giannis, Athanassios, Topouzis, Stavros, Papapetropoulos, Andreas, Spyroulias, Georgios A., Stuehr, Dennis J., Ghosh, Arnab, Dai, Yue, Misra, Saurav, Tchernychev, Boris, Jung, Joon, Liu, Guang, Silos-Santiago, Inmaculada, Hannig, Gerhard, Dao, Vu Thao-Vi, Deile, Martin, Nedvetsky, Pavel I., Güldner, Andreas, Ibarra-Alvarado, César, Gödecke, Axel, Schmidt, Harald H. H. W., Vachaviolos, Angelos, Gerling, Andrea, Thunemann, Martin, Lutz, Stefan Z., Häring, Hans-Ulrich, Krüger, Marcel A., Pichler, Bernd J., Shipston, Michael J., Feil, Susanne, Feil, Robert, Vandenwijngaert, Sara, Ledsky, Clara D., Agha, Obiajulu, Hu, Dongjian, Domian, Ibrahim J., Buys, Emmanuel S., Newton-Cheh, Christopher, Bloch, Donald B., Voussen, Barbara, Beck, Katharina, Mauro, Nadine, Keppler, Jonas, Friebe, Andreas, Ferreira, Wilson A., Chweih, Hanan, Brito, Pamela L., Almeida, Camila B., Penteado, Carla F. F., Saad, Sara S. O., Costa, Fernando F., Frenette, Paul S., Brockschnieder, Damian, Stasch, Johannes-Peter, Sandner, Peter, Conran, Nicola, Zimmer, Daniel P., Tobin, Jenny, Shea, Courtney, Sarno, Renee, Long, Kimberly, Jacobson, Sarah, Tang, Kim, Germano, Peter, Wakefield, James, Banijamali, Ali, Im, G-Yoon Jamie, Sheppeck, James E., Profy, Albert T., Todd Milne, G., Currie, Mark G., Masferrer, Jaime L.
Publicado 2017