A Novel Class of Norovirus Inhibitors Targeting the Viral Protease with Potent Antiviral Activity In Vitro and In Vivo

por Van Dycke, Jana, Dai, Wenhao, Stylianidou, Zoe, Li, Jian, Cuvry, Arno, Roux, Emma, Li, Bingqian, Rymenants, Jasper, Bervoets, Lindsey, de Witte, Peter, Liu, Hong, Neyts, Johan, Rocha-Pereira, Joana
Publicado 2021

Updated vaccine protects against SARS-CoV-2 variants including Omicron (B.1.1.529) and prevents transmission in hamsters

por Sharma, Sapna, Vercruysse, Thomas, Sanchez-Felipe, Lorena, Kerstens, Winnie, Rasulova, Madina, Bervoets, Lindsey, De Keyzer, Carolien, Abdelnabi, Rana, Foo, Caroline S., Lemmens, Viktor, Van Looveren, Dominique, Maes, Piet, Baele, Guy, Weynand, Birgit, Lemey, Philippe, Neyts, Johan, Thibaut, Hendrik Jan, Dallmeier, Kai
Publicado 2022

Favipiravir at high doses has potent antiviral activity in SARS-CoV-2−infected hamsters, whereas hydroxychloroquine lacks activity

por Kaptein, Suzanne J. F., Jacobs, Sofie, Langendries, Lana, Seldeslachts, Laura, ter Horst, Sebastiaan, Liesenborghs, Laurens, Hens, Bart, Vergote, Valentijn, Heylen, Elisabeth, Barthelemy, Karine, Maas, Elke, De Keyzer, Carolien, Bervoets, Lindsey, Rymenants, Jasper, Van Buyten, Tina, Zhang, Xin, Abdelnabi, Rana, Pang, Juanita, Williams, Rachel, Thibaut, Hendrik Jan, Dallmeier, Kai, Boudewijns, Robbert, Wouters, Jens, Augustijns, Patrick, Verougstraete, Nick, Cawthorne, Christopher, Breuer, Judith, Solas, Caroline, Weynand, Birgit, Annaert, Pieter, Spriet, Isabel, Vande Velde, Greetje, Neyts, Johan, Rocha-Pereira, Joana, Delang, Leen
Publicado 2020

STAT2 signaling restricts viral dissemination but drives severe pneumonia in SARS-CoV-2 infected hamsters

por Boudewijns, Robbert, Thibaut, Hendrik Jan, Kaptein, Suzanne J. F., Li, Rong, Vergote, Valentijn, Seldeslachts, Laura, Van Weyenbergh, Johan, De Keyzer, Carolien, Bervoets, Lindsey, Sharma, Sapna, Liesenborghs, Laurens, Ma, Ji, Jansen, Sander, Van Looveren, Dominique, Vercruysse, Thomas, Wang, Xinyu, Jochmans, Dirk, Martens, Erik, Roose, Kenny, De Vlieger, Dorien, Schepens, Bert, Van Buyten, Tina, Jacobs, Sofie, Liu, Yanan, Martí-Carreras, Joan, Vanmechelen, Bert, Wawina-Bokalanga, Tony, Delang, Leen, Rocha-Pereira, Joana, Coelmont, Lotte, Chiu, Winston, Leyssen, Pieter, Heylen, Elisabeth, Schols, Dominique, Wang, Lanjiao, Close, Lila, Matthijnssens, Jelle, Van Ranst, Marc, Compernolle, Veerle, Schramm, Georg, Van Laere, Koen, Saelens, Xavier, Callewaert, Nico, Opdenakker, Ghislain, Maes, Piet, Weynand, Birgit, Cawthorne, Christopher, Vande Velde, Greetje, Wang, Zhongde, Neyts, Johan, Dallmeier, Kai
Publicado 2020