Mycobacterial cell wall biosynthesis: a multifaceted antibiotic target

por ABRAHAMS, KATHERINE A., BESRA, GURDYAL S.
Publicado 2018

Synthesis and recycling of the mycobacterial cell envelope

por Abrahams, Katherine A, Besra, Gurdyal S
Publicado 2021

Mycobacterial drug discovery

por Abrahams, Katherine A., Besra, Gurdyal S.
Publicado 2020

The role of triacylglycerols and repurposing DGAT1 inhibitors for the treatment of Mycobacterium tuberculosis

por Moorey, Alice R., Besra, Gurdyal S.
Publicado 2022

Synthesis and biological evaluation of NAS-21 and NAS-91 analogues as potential inhibitors of the mycobacterial FAS-II dehydratase enzyme Rv0636

por Bhowruth, Veemal, Brown, Alistair K., Besra, Gurdyal S.
Publicado 2008

Synthesis of a Versatile Building Block for the Preparation of 6-N-Derivatized α-Galactosyl Ceramides: Rapid Access to Biologically Active Glycolipids

por Jervis, Peter J., Cox, Liam R., Besra, Gurdyal S.
Publicado 2010

Structural and functional analysis of the solute-binding protein UspC from Mycobacterium tuberculosis that is specific for amino sugars

por Fullam, Elizabeth, Prokes, Ivan, Fütterer, Klaus, Besra, Gurdyal S.
Publicado 2016

The thick waxy coat of mycobacteria, a protective layer against antibiotics and the host's immune system

por Batt, Sarah M., Minnikin, David E., Besra, Gurdyal S.
Publicado 2020

Calreticulin Controls the Rate of Assembly of CD1d Molecules in the Endoplasmic Reticulum

por Zhu, Yajuan, Zhang, Wei, Veerapen, Natacha, Besra, Gurdyal, Cresswell, Peter
Publicado 2010

Synthesis of truncated analogues of the iNKT cell agonist, α-galactosyl ceramide (KRN7000), and their biological evaluation

por Veerapen, Natacha, Reddington, Faye, Salio, Mariolina, Cerundolo, Vincenzo, Besra, Gurdyal S.
Publicado 2011

Elucidation of a protein-protein interaction network involved in Corynebacterium glutamicum cell wall biosynthesis as determined by bacterial two-hybrid analysis

por Jankute, Monika, Byng, Charlotte V., Alderwick, Luke J., Besra, Gurdyal S.
Publicado 2014

Synthesis and biological activity of α-l-fucosyl ceramides, analogues of the potent agonist, α-d-galactosyl ceramide KRN7000

por Veerapen, Natacha, Reddington, Faye, Bricard, Gabriel, Porcelli, Steven A., Besra, Gurdyal S.
Publicado 2010

Inhibition of Escherichia coli glycosyltransferase MurG and Mycobacterium tuberculosis Gal transferase by uridine-linked transition state mimics

por Trunkfield, Amy E., Gurcha, Sudagar S., Besra, Gurdyal S., Bugg, Timothy D.H.
Publicado 2010

Lipoarabinomannan and related glycoconjugates: structure, biogenesis and role in Mycobacterium tuberculosis physiology and host–pathogen interaction

por Mishra, Arun K, Driessen, Nicole N, Appelmelk, Ben J, Besra, Gurdyal S
Publicado 2011

Antibiotics and resistance: the two-sided coin of the mycobacterial cell wall

por Batt, Sarah M., Burke, Christopher E., Moorey, Alice R., Besra, Gurdyal S.
Publicado 2020

Tuberculosis diagnostics: overcoming ancient challenges with modern solutions

por MacGregor-Fairlie, Michael, Wilkinson, Samuel, Besra, Gurdyal S., Goldberg Oppenheimer, Pola
Publicado 2020

Loss of a Mycobacterial Gene Encoding a Reductase Leads to an Altered Cell Wall Containing β-oxo- Mycolic Acid Analogs and Accumulation of Ketones

por Bhatt, Apoorva, Brown, Alistair K., Singh, Albel, Minnikin, David E., Besra, Gurdyal S.
Publicado 2008

Platensimycin Activity against Mycobacterial β-Ketoacyl-ACP Synthases

por Brown, Alistair K., Taylor, Rebecca C., Bhatt, Apoorva, Fütterer, Klaus, Besra, Gurdyal S.
Publicado 2009

Identification of Novel Mt-Guab2 Inhibitor Series Active against M. tuberculosis

por Usha, Veeraraghavan, Hobrath, Judith V., Gurcha, Sudagar S., Reynolds, Robert C., Besra, Gurdyal S.
Publicado 2012

Differential effects of Mycobacterium bovis - derived polar and apolar lipid fractions on bovine innate immune cells

por Pirson, Chris, Jones, Gareth J, Steinbach, Sabine, Besra, Gurdyal S, Vordermeier, H Martin
Publicado 2012