Monitoring TRPC7 Conformational Changes by BRET Following GPCR Activation

por Pétigny, Cécile, Dumont, Audrey-Ann, Giguère, Hugo, Collette, Audrey, Holleran, Brian J., Iftinca, Mircea, Altier, Christophe, Besserer-Offroy, Élie, Auger-Messier, Mannix, Leduc, Richard
Publicado 2022

Structure-Based Virtual Screening of Ultra-Large Library Yields Potent Antagonists for a Lipid GPCR

por Sadybekov, Arman A., Brouillette, Rebecca L., Marin, Egor, Sadybekov, Anastasiia V., Luginina, Aleksandra, Gusach, Anastasiia, Mishin, Alexey, Besserer-Offroy, Élie, Longpré, Jean-Michel, Borshchevskiy, Valentin, Cherezov, Vadim, Sarret, Philippe, Katritch, Vsevolod
Publicado 2020

Data set describing the in vitro biological activity of JMV2009, a novel silylated neurotensin(8–13) analog

por Besserer-Offroy, Élie, Tétreault, Pascal, Brouillette, Rebecca L, René, Adeline, Murza, Alexandre, Fanelli, Roberto, Kirby, Karyn, Parent, Alexandre, Dubuc, Isabelle, Beaudet, Nicolas, Côté, Jérôme, Longpré, Jean-Michel, Martinez, Jean, Cavelier, Florine, Sarret, Philippe
Publicado 2020

Structural insights on ligand recognition at the human leukotriene B4 receptor 1

por Michaelian, Nairie, Sadybekov, Anastasiia, Besserer-Offroy, Élie, Han, Gye Won, Krishnamurthy, Harini, Zamlynny, Beata A., Fradera, Xavier, Siliphaivanh, Phieng, Presland, Jeremy, Spencer, Kerrie B., Soisson, Stephen M., Popov, Petr, Sarret, Philippe, Katritch, Vsevolod, Cherezov, Vadim
Publicado 2021

Structural basis of ligand selectivity and disease mutations in cysteinyl leukotriene receptors

por Gusach, Anastasiia, Luginina, Aleksandra, Marin, Egor, Brouillette, Rebecca L., Besserer-Offroy, Élie, Longpré, Jean-Michel, Ishchenko, Andrii, Popov, Petr, Patel, Nilkanth, Fujimoto, Taku, Maruyama, Toru, Stauch, Benjamin, Ergasheva, Margarita, Romanovskaia, Daria, Stepko, Anastasiia, Kovalev, Kirill, Shevtsov, Mikhail, Gordeliy, Valentin, Han, Gye Won, Katritch, Vsevolod, Borshchevskiy, Valentin, Sarret, Philippe, Mishin, Alexey, Cherezov, Vadim
Publicado 2019

Structure-based mechanism of cysteinyl leukotriene receptor inhibition by antiasthmatic drugs

por Luginina, Aleksandra, Gusach, Anastasiia, Marin, Egor, Mishin, Alexey, Brouillette, Rebecca, Popov, Petr, Shiriaeva, Anna, Besserer-Offroy, Élie, Longpré, Jean-Michel, Lyapina, Elizaveta, Ishchenko, Andrii, Patel, Nilkanth, Polovinkin, Vitaly, Safronova, Nadezhda, Bogorodskiy, Andrey, Edelweiss, Evelina, Hu, Hao, Weierstall, Uwe, Liu, Wei, Batyuk, Alexander, Gordeliy, Valentin, Han, Gye Won, Sarret, Philippe, Katritch, Vsevolod, Borshchevskiy, Valentin, Cherezov, Vadim
Publicado 2019