Optimization of Tubulysin Antibody–Drug Conjugates: A Case Study in Addressing ADC Metabolism

por Tumey, L. Nathan, Leverett, Carolyn A., Vetelino, Beth, Li, Fengping, Rago, Brian, Han, Xiaogang, Loganzo, Frank, Musto, Sylvia, Bai, Guoyun, Sukuru, Sai Chetan K., Graziani, Edmund I., Puthenveetil, Sujiet, Casavant, Jeffrey, Ratnayake, Anokha, Marquette, Kimberly, Hudson, Sarah, Doppalapudi, Venkata Ramana, Stock, Joseph, Tchistiakova, Lioudmila, Bessire, Andrew J., Clark, Tracey, Lucas, Judy, Hosselet, Christine, O’Donnell, Christopher J., Subramanyam, Chakrapani
Publicado 2016