Immune Tolerance Maintained by Cooperative Interactions between T Cells and Antigen Presenting Cells Shapes a Diverse TCR Repertoire

por Best, Katharine, Chain, Benny, Watkins, Chris
Publicado 2015

Computational analysis of stochastic heterogeneity in PCR amplification efficiency revealed by single molecule barcoding

por Best, Katharine, Oakes, Theres, Heather, James M., Shawe-Taylor, John, Chain, Benny
Publicado 2015

Zika virus dynamics: Effects of inoculum dose, the innate immune response and viral interference

por Best, Katharine, Barouch, Dan H., Guedj, Jeremie, Ribeiro, Ruy M., Perelson, Alan S.
Publicado 2021

The impact of DAMP-mediated inflammation in severe COVID-19 and related disorders

por Parthasarathy, Upasana, Martinelli, Roberta, Vollmann, Elisabeth H., Best, Katharine, Therien, Alex G.
Publicado 2022

T-cell receptor repertoires share a restricted set of public and abundant CDR3 sequences that are associated with self-related immunity

por Madi, Asaf, Shifrut, Eric, Reich-Zeliger, Shlomit, Gal, Hilah, Best, Katharine, Ndifon, Wilfred, Chain, Benjamin, Cohen, Irun R., Friedman, Nir
Publicado 2014

Dynamic Perturbations of the T-Cell Receptor Repertoire in Chronic HIV Infection and following Antiretroviral Therapy

por Heather, James M., Best, Katharine, Oakes, Theres, Gray, Eleanor R., Roe, Jennifer K., Thomas, Niclas, Friedman, Nir, Noursadeghi, Mahdad, Chain, Benjamin
Publicado 2016

Specificity, Privacy, and Degeneracy in the CD4 T Cell Receptor Repertoire Following Immunization

por Sun, Yuxin, Best, Katharine, Cinelli, Mattia, Heather, James M., Reich-Zeliger, Shlomit, Shifrut, Eric, Friedman, Nir, Shawe-Taylor, John, Chain, Benny
Publicado 2017

Feature selection using a one dimensional naïve Bayes’ classifier increases the accuracy of support vector machine classification of CDR3 repertoires

por Cinelli, Mattia, Sun, , Yuxin, Best, Katharine, Heather, James M, Reich-Zeliger, Shlomit, Shifrut, Eric, Friedman, Nir, Shawe-Taylor, John, Chain, Benny
Publicado 2017

Pericyte derived chemokines amplify neutrophil recruitment across the cerebrovascular endothelial barrier

por Gil, Eliza, Venturini, Cristina, Stirling, David, Turner, Carolin, Tezera, Liku B., Ercoli, Giuseppe, Baker, Tina, Best, Katharine, Brown, Jeremy S., Noursadeghi, Mahdad
Publicado 2022

Tracking global changes induced in the CD4 T-cell receptor repertoire by immunization with a complex antigen using short stretches of CDR3 protein sequence

por Thomas, Niclas, Best, Katharine, Cinelli, Mattia, Reich-Zeliger, Shlomit, Gal, Hilah, Shifrut, Eric, Madi, Asaf, Friedman, Nir, Shawe-Taylor, John, Chain, Benny
Publicado 2014

The T Cell Response to the Contact Sensitizer Paraphenylenediamine Is Characterized by a Polyclonal Diverse Repertoire of Antigen-Specific Receptors

por Oakes, Theres, Popple, Amy Lee, Williams, Jason, Best, Katharine, Heather, James M., Ismail, Mazlina, Maxwell, Gavin, Gellatly, Nichola, Dearman, Rebecca J., Kimber, Ian, Chain, Benny
Publicado 2017

Transcriptional Profiling of Endobronchial Ultrasound-Guided Lymph Node Samples Aids Diagnosis of Mediastinal Lymphadenopathy

por Tomlinson, Gillian S., Thomas, Niclas, Chain, Benjamin M., Best, Katharine, Simpson, Nandi, Hardavella, Georgia, Brown, James, Bhowmik, Angshu, Navani, Neal, Janes, Samuel M., Miller, Robert F., Noursadeghi, Mahdad
Publicado 2016

Blood transcriptomic diagnosis of pulmonary and extrapulmonary tuberculosis

por Roe, Jennifer K, Thomas, Niclas, Gil, Eliza, Best, Katharine, Tsaliki, Evdokia, Morris‑Jones, Stephen, Stafford, Sian, Simpson, Nandi, Witt, Karolina D, Chain, Benjamin, Miller, Robert F, Martineau, Adrian, Noursadeghi, Mahdad
Publicado 2016

Quantitative Characterization of the T Cell Receptor Repertoire of Naïve and Memory Subsets Using an Integrated Experimental and Computational Pipeline Which Is Robust, Economical,...

por Oakes, Theres, Heather, James M., Best, Katharine, Byng-Maddick, Rachel, Husovsky, Connor, Ismail, Mazlina, Joshi, Kroopa, Maxwell, Gavin, Noursadeghi, Mahdad, Riddell, Natalie, Ruehl, Tabea, Turner, Carolin T., Uddin, Imran, Chain, Benny
Publicado 2017

Very early life microbiome and metabolome correlates with primary vaccination variability in children

por Shaffer, Michael, Best, Katharine, Tang, Catherine, Liang, Xue, Schulz, Steven, Gonzalez, Eduardo, White, Cory H., Wyche, Thomas P., Kang, John, Wesseling, Hendrik, Topçuoğlu, Begüm D., Cairns, Thomas, Sana, Theodore R., Kaufhold, Robin M., Maritz, Julia M., Woelk, Christopher H., Swaminathan, Gokul, Norton, James E., Pichichero, Michael E.
Publicado 2023