Th2 cells inhibit growth of colon and pancreas cancers by promoting anti-tumorigenic responses from macrophages and eosinophils

por Jacenik, Damian, Karagiannidis, Ioannis, Beswick, Ellen J.
Publicado 2022

MK2 drives progression of pancreas and colon cancers by suppressing CD8(+) T cell cytotoxic function and is a potential immunotherapy target

por Jacenik, Damian, Lebish, Eric J., Beswick, Ellen J.
Publicado 2023

Role of PD-L1 in Gut Mucosa Tolerance and Chronic Inflammation

por Chulkina, Marina, Beswick, Ellen J., Pinchuk, Irina V.
Publicado 2020

MK2 Promotes the Development and Progression of Pancreatic Neuroendocrine Tumors Mediated by Macrophages and Metabolomic Factors

por Jacenik, Damian, Lebish, Eric J., Beswick, Ellen J.
Publicado 2022

Staphylococcal Enterotoxins

por Pinchuk, Irina V., Beswick, Ellen J., Reyes, Victor E.
Publicado 2010

MK2: an unrecognized regulator of tumor promoting macrophages in colorectal cancer?

por Castillo, Eliseo F., Ray, Anita L., Beswick, Ellen J.
Publicado 2016

The MK2 pathway is linked to G-CSF, cytokine production and metastasis in gastric cancer: a novel intercorrelation analysis approach

por Qeadan, Fares, Bansal, Pranshu, Hanson, Joshua A., Beswick, Ellen J.
Publicado 2020

Chronic Macrophage Migration Inhibitory Factor Exposure Induces Mesenchymal Epithelial Transition and Promotes Gastric and Colon Cancers

por Morris, Katherine T., Nofchissey, Robert A., Pinchuk, Irina V., Beswick, Ellen J.
Publicado 2014

G protein-coupled estrogen receptor in colon function, immune regulation and carcinogenesis

por Jacenik, Damian, Beswick, Ellen J, Krajewska, Wanda M, Prossnitz, Eric R
Publicado 2019

MK2 Inhibitors as a Potential Crohn’s Disease Treatment Approach for Regulating MMP Expression, Cleavage of Checkpoint Molecules and T Cell Activity

por Lebish, Eric J., Morgan, Natalie J., Valentine, John F., Beswick, Ellen J.
Publicado 2022

Cytokine release syndrome in COVID-19: Innate immune, vascular, and platelet pathogenic factors differ in severity of disease and sex

por Petrey, Aaron C, Qeadan, Fares, Middleton, Elizabeth A, Pinchuk, Irina V, Campbell, Robert A, Beswick, Ellen J
Publicado 2020

G-CSF and G-CSFR Modulate CD4 and CD8 T Cell Responses to Promote Colon Tumor Growth and Are Potential Therapeutic Targets

por Karagiannidis, Ioannis, Jerman, Stephanie J., Jacenik, Damian, Phinney, Brandon B., Yao, Ruoxin, Prossnitz, Eric R., Beswick, Ellen J.
Publicado 2020

Differential Susceptibility of Human Peripheral Blood T Cells to Suppression by Environmental Levels of Sodium Arsenite and Monomethylarsonous Acid

por Burchiel, Scott W., Lauer, Fredine T., Beswick, Ellen J., Gandolfi, A. Jay, Parvez, Faruque, Liu, Ke Jian, Hudson, Laurie G.
Publicado 2014

MK2 Regulates Macrophage Chemokine Activity and Recruitment to Promote Colon Tumor Growth

por Phinney, Brandon B., Ray, Anita L., Peretti, Amanda S., Jerman, Stephanie J., Grim, Carl, Pinchuk, Irina V., Beswick, Ellen J.
Publicado 2018

Stromal Cells Induce Th17 during Helicobacter pylori Infection and in the Gastric Tumor Microenvironment

por Pinchuk, Irina V., Morris, Katherine T., Nofchissey, Robert A., Earley, Rachel B., Wu, Jeng-Yih, Ma, Thomas Y., Beswick, Ellen J.
Publicado 2013

G-CSF and G-CSFR Induce a Pro-Tumorigenic Macrophage Phenotype to Promote Colon and Pancreas Tumor Growth

por Karagiannidis, Ioannis, de Santana Van Vilet, Eliane, Said Abu Egal, Erika, Phinney, Brandon, Jacenik, Damian, Prossnitz, Eric R., Beswick, Ellen J.
Publicado 2020

COVID-19 generates hyaluronan fragments that directly induce endothelial barrier dysfunction

por Queisser, Kimberly A., Mellema, Rebecca A., Middleton, Elizabeth A., Portier, Irina, Manne, Bhanu Kanth, Denorme, Frederik, Beswick, Ellen J., Rondina, Matthew T., Campbell, Robert A., Petrey, Aaron C.
Publicado 2021

Anti-G-CSF treatment induces protective tumor immunity in mouse colon cancer by promoting NK cell, macrophage and T cell responses

por Morris, Katherine T., Castillo, Eliseo F., Ray, Anita L., Weston, Lea L., Nofchissey, Robert A., Hanson, Joshua A., Samedi, Von G., Pinchuk, Irina V., Hudson, Laurie G., Beswick, Ellen J.
Publicado 2015

Expression of Programmed Death-Ligand 1 by Human Colonic CD90(+) Stromal Cells Differs Between Ulcerative Colitis and Crohn’s Disease and Determines Their Capacity to Suppress Th1...

por Beswick, Ellen J., Grim, Carl, Singh, Abinav, Aguirre, Jose E., Tafoya, Marissa, Qiu, Suimin, Rogler, Gerhard, McKee, Rohini, Samedi, Von, Ma, Thomas Y., Reyes, Victor E., Powell, Don W., Pinchuk, Irina V.
Publicado 2018

MAPKAPK2 (MK2) inhibition mediates radiation-induced inflammatory cytokine production and tumor growth in head and neck squamous cell carcinoma

por Berggren, Kiersten L., Cruz, Sebastian Restrepo, Hixon, Michael D, Cowan, Andrew, Keysar, Stephen B., Craig, Stephanie, James, Jacqueline, Barry, Marc, Ozbun, Michelle A., Jimeno, Antonio, McCance, Dennis J., Beswick, Ellen J., Gan, Gregory N.
Publicado 2019