NSMCE2, a novel super-enhancer-regulated gene, is linked to poor prognosis and therapy resistance in breast cancer

por Di Benedetto, Carolina, Oh, Justin, Choudhery, Zainab, Shi, Weiquan, Valdes, Gilmer, Betancur, Paola
Publicado 2022

Enhancer Clusters Drive Type I Interferon-Induced TRAIL Overexpression in Cancer, and Its Intracellular Protein Accumulation Fails to Induce Apoptosis

por Di Benedetto, Carolina, Khan, Taimoor, Serrano-Saenz, Santiago, Rodriguez-Lemus, Anthony, Klomsiri, Chananat, Beutel, Tim-Mathis, Thach, Alysia, Walczak, Henning, Betancur, Paola
Publicado 2023

Activation of JUN in fibroblasts promotes pro-fibrotic programme and modulates protective immunity

por Cui, Lu, Chen, Shih-Yu, Lerbs, Tristan, Lee, Jin-Wook, Domizi, Pablo, Gordon, Sydney, Kim, Yong-hun, Nolan, Garry, Betancur, Paola, Wernig, Gerlinde
Publicado 2020

CD47 blocking antibodies restore phagocytosis and prevent atherosclerosis

por Kojima, Yoko, Volkmer, Jens-Peter, McKenna, Kelly, Civelek, Mete, Lusis, A. Jake, Miller, Clint, Direnzo, Daniel, Nanda, Vivek, Ye, Jianqin, Connolly, Andrew, Schadt, Eric, Quertermous, Thomas, Betancur, Paola, Maegdefessel, Lars, Perisic, Ljubica, Hedin, Ulf, Weissman, Irv, Leeper, Nicholas J.
Publicado 2016

A CD47-associated super-enhancer links pro-inflammatory signalling to CD47 upregulation in breast cancer

por Betancur, Paola A., Abraham, Brian J., Yiu, Ying Y., Willingham, Stephen B., Khameneh, Farnaz, Zarnegar, Mark, Kuo, Angera H., McKenna, Kelly, Kojima, Yoko, Leeper, Nicholas J., Ho, Po, Gip, Phung, Swigut, Tomek, Sherwood, Richard I., Clarke, Michael F., Somlo, George, Young, Richard A., Weissman, Irving L.
Publicado 2017