Detection of SHV β-lactamases in Gram-negative bacilli using fluorescein-labeled antibodies

por Hujer, Andrea M, Keslar, Karen S, Dietenberger, Nicole J, Bethel, Christopher R, Endimiani, Andrea, Bonomo, Robert A
Publicado 2009

2178. Resistance to Cefepime/Taniborbactam in NDM-1 -Are We Losing the Battle against MDROs?

por Ono, Daisuke, Mojica, Maria F, Bethel, Christopher R, Ishii, Yoshikazu, Moreno, Diego, Vila, Alejandro J, Bonomo, Robert A
Publicado 2023

2160. Emergence of INDEL Mutations in KPC-2: Insights into Ceftazidime-Avibactam and Imipenem-Relebactam Efficacy

por Brunetti, Florencia, Bethel, Christopher R, Sanz, María Belén, Pasterán, Fernando, Gutkind, Gabriel, Gomez, Sonia, Bonomo, Robert A, Power, Pablo
Publicado 2023

Structures of SHV-1 β-Lactamase with Penem and Penam Sulfone Inhibitors That Form Cyclic Intermediates Stabilized by Carbonyl Conjugation

por Ke, Wei, Pattanaik, Priyaranjan, Bethel, Christopher R., Sheri, Anjaneyulu, Buynak, John D., Bonomo, Robert A., van den Akker, Focco
Publicado 2012

Collateral Changes in Cell Physiology Associated with ADC-7 β-Lactamase Expression in Acinetobacter baumannii

por Colquhoun, Jennifer M., Farokhyfar, Marjan, Anderson, Alexander C., Bethel, Christopher R., Bonomo, Robert A., Clarke, Anthony J., Rather, Philip N.
Publicado 2023

The Novel β-Lactamase Inhibitor, ETX-2514, in Combination with Sulbactam Effectively Inhibits Acinetobacter baumannii

por Barnes, Melissa D, Bethel, Christopher R, Rutter, Joseph D, Akker, Focco Van Den, Papp-Wallace, Krisztina M, Bonomo, Robert A
Publicado 2017

Following Drug Uptake and Reactions inside Escherichia coli Cells by Raman Microspectroscopy

por Heidari Torkabadi, Hossein, Bethel, Christopher R., Papp-Wallace, Krisztina M., de Boer, Piet A. J., Bonomo, Robert A., Carey, Paul R.
Publicado 2014

2806. The Mechanism of β-Lactam Antibiotic Action: Structural Analysis of Mycobacterium abscessus l,d-Transpeptidases, d,d-Carboxypeptidase and penicillin-binding-proteins binding...

por Shin, Eunjeong, Nantongo, Mary, Dousa, Khalid M, Bethel, Christopher R, Taracila, Magdalena A, Kreiswirth, Barry N, Holland, Steven M, Bonomo, Robert A
Publicado 2023

OXA-23 β-Lactamase Overexpression in Acinetobacter baumannii Drives Physiological Changes Resulting in New Genetic Vulnerabilities

por Colquhoun, Jennifer M., Farokhyfar, Marjan, Hutcheson, Anna R., Anderson, Alexander, Bethel, Christopher R., Bonomo, Robert A., Clarke, Anthony J., Rather, Philip N.
Publicado 2021

Insights Into the Inhibition of MOX-1 β-Lactamase by S02030, a Boronic Acid Transition State Inhibitor

por Ishikawa, Tatsuya, Furukawa, Nayuta, Caselli, Emilia, Prati, Fabio, Taracila, Magdalena A., Bethel, Christopher R., Ishii, Yoshikazu, Shimizu-Ibuka, Akiko, Bonomo, Robert A.
Publicado 2021

The Effectiveness of Imipenem–Relebactam against Ceftazidime-Avibactam Resistant Variants of the KPC-2 β-Lactamase

por Papp-Wallace, Krisztina M., Barnes, Melissa D., Taracila, Magdalena A., Bethel, Christopher R., Rutter, Joseph D., Zeiser, Elise T., Young, Katherine, Bonomo, Robert A.
Publicado 2023

Penam Sulfones and β-Lactamase Inhibition: SA2-13 and the Importance of the C2 Side Chain Length and Composition

por Rodkey, Elizabeth A., Winkler, Marisa L., Bethel, Christopher R., Pagadala, Sundar Ram Reddy, Buynak, John D., Bonomo, Robert A., van den Akker, Focco
Publicado 2014

AAI101, a Novel β-Lactamase Inhibitor: Microbiological and Enzymatic Profiling

por Papp-Wallace, Krisztina M, Bethel, Christopher R, Barnes, Melissa D, Rutter, Joseph D, Taracila, Magdalena A, Bajaksouzian, Saralee, Jacobs, Michael R, Bonomo, Robert A
Publicado 2017

Penicillanic Acid Sulfones Inactivate the Extended-Spectrum β-Lactamase CTX-M-15 through Formation of a Serine-Lysine Cross-Link: an Alternative Mechanism of β-Lactamase Inhibition...

por Hinchliffe, Philip, Tooke, Catherine L., Bethel, Christopher R., Wang, Benlian, Arthur, Christopher, Heesom, Kate J., Shapiro, Stuart, Schlatzer, Daniela M., Papp-Wallace, Krisztina M., Bonomo, Robert A., Spencer, James
Publicado 2022

1385. Mechanism-Based, In Vitro Inhibition of Mycobacterium abscessus: Assessing β-Lactam Therapy

por Dousa, Khalid M, Kurz, Sebastian G, Bethel, Christopher R, Barnes, Melissa D, Taracilla, Magdalena A, Selvaraju, Suresh, Jacobs, Michael R, Kreiswirth, Barry, Kasperbauer, Shannon H, Daley, Charles L, Bonomo, Robert A
Publicado 2019

Detecting a Quasi-stable Imine Species on the Reaction Pathway of SHV-1 β-Lactamase and 6β-(Hydroxymethyl)penicillanic Acid Sulfone

por Che, Tao, Rodkey, Elizabeth A., Bethel, Christopher R., Shanmugam, Sivaprakash, Ding, Zhe, Pusztai-Carey, Marianne, Nottingham, Michael, Chai, Weirui, Buynak, John D., Bonomo, Robert A., van den Akker, Focco, Carey, Paul R.
Publicado 2014

Deciphering the Evolution of Cephalosporin Resistance to Ceftolozane-Tazobactam in Pseudomonas aeruginosa

por Barnes, Melissa D., Taracila, Magdalena A., Rutter, Joseph D., Bethel, Christopher R., Galdadas, Ioannis, Hujer, Andrea M., Caselli, Emilia, Prati, Fabio, Dekker, John P., Papp-Wallace, Krisztina M., Haider, Shozeb, Bonomo, Robert A.
Publicado 2018

Inhibiting Mycobacterium abscessus Cell Wall Synthesis: Using a Novel Diazabicyclooctane β-Lactamase Inhibitor To Augment β-Lactam Action

por Dousa, Khalid M., Nguyen, David C., Kurz, Sebastian G., Taracila, Magdalena A., Bethel, Christopher R., Schinabeck, William, Kreiswirth, Barry N., Brown, Sheldon T., Boom, W. Henry, Hotchkiss, Richard S., Remy, Kenneth E., Jacono, Frank J., Daley, Charles L., Holland, Steven M., Miller, Alita A., Bonomo, Robert A.
Publicado 2022

Boronic Acid Transition State Inhibitors as Potent Inactivators of KPC and CTX-M β-Lactamases: Biochemical and Structural Analyses

por Alsenani, Tahani A., Rodríguez, María Margarita, Ghiglione, Barbara, Taracila, Magdalena A., Mojica, Maria F., Rojas, Laura J., Hujer, Andrea M., Gutkind, Gabriel, Bethel, Christopher R., Rather, Philip N., Introvigne, Maria Luisa, Prati, Fabio, Caselli, Emilia, Power, Pablo, van den Akker, Focco, Bonomo, Robert A.
Publicado 2023

Targeting Multidrug-Resistant Acinetobacter spp.: Sulbactam and the Diazabicyclooctenone β-Lactamase Inhibitor ETX2514 as a Novel Therapeutic Agent

por Barnes, Melissa D., Kumar, Vijay, Bethel, Christopher R., Moussa, Samir H., O’Donnell, John, Rutter, Joseph D., Good, Caryn E., Hujer, Kristine M., Hujer, Andrea M., Marshall, Steve H., Kreiswirth, Barry N., Richter, Sandra S., Rather, Philip N., Jacobs, Michael R., Papp-Wallace, Krisztina M., van den Akker, Focco, Bonomo, Robert A.
Publicado 2019