Current status on Alzheimer disease molecular genetics: from past, to present, to future

por Bettens, Karolien, Sleegers, Kristel, Van Broeckhoven, Christine
Publicado 2010

Allorecognition of HLA-C Mismatches by CD8(+) T Cells in Hematopoietic Stem Cell Transplantation Is a Complex Interplay between Mismatched Peptide-Binding Region Residues, HLA-C Ex...

por Bettens, Florence, Buhler, Stéphane, Tiercy, Jean-Marie
Publicado 2016

CD8+ T-Cell Repertoire in Human Leukocyte Antigen Class I-Mismatched Alloreactive Immune Response

por Bettens, Florence, Calderin Sollet, Zuleika, Buhler, Stéphane, Villard, Jean
Publicado 2021

The hunt for reactive alkynes in bio-orthogonal click reactions: insights from mechanochemical and conceptual DFT calculations

por Bettens, Tom, Alonso, Mercedes, Geerlings, Paul, De Proft, Frank
Publicado 2019

Alkaline Earth Metals Activate N(2) and CO in Cubic Complexes Just Like Transition Metals: A Conceptual Density Functional Theory and Energy Decomposition Analysis Study

por Bettens, Tom, Pan, Sudip, De Proft, Frank, Frenking, Gernot, Geerlings, Paul
Publicado 2020

Ambident Nucleophilic Substitution: Understanding Non‐HSAB Behavior through Activation Strain and Conceptual DFT Analyses

por Bettens, Tom, Alonso, Mercedes, De Proft, Frank, Hamlin, Trevor A., Bickelhaupt, F. Matthias
Publicado 2020

Mechanochemically Triggered Topology Changes in Expanded Porphyrins

por Bettens, Tom, Hoffmann, Marvin, Alonso, Mercedes, Geerlings, Paul, Dreuw, Andreas, De Proft, Frank
Publicado 2021

Conceptual density functional theory under pressure: Part I. XP-PCM method applied to atoms

por Eeckhoudt, J., Bettens, T., Geerlings, P., Cammi, R., Chen, B., Alonso, M., De Proft, F.
Publicado 2022

Regulation of HLA class I expression by non-coding gene variations

por Bettens, Florence, Ongen, Halit, Rey, Guillaume, Buhler, Stéphane, Calderin Sollet, Zuleika, Dermitzakis, Emmanouil, Villard, Jean
Publicado 2022

A Quantum Chemical Deep-Dive into the π-π Interactions of 3-Methylindole and Its Halogenated Derivatives—Towards an Improved Ligand Design and Tryptophan Stacking

por Van Lommel, Ruben, Bettens, Tom, Barlow, Thomas M. A., Bertouille, Jolien, Ballet, Steven, De Proft, Frank
Publicado 2022

PROTOCOL: Interview and interrogation methods and their effects on true and false confessions: An update and extension

por Catlin, Mary, Wilson, David B., Redlich, Allison D., Bettens, Talley, Meissner, Christian A., Bhatt, Sujeeta, Brandon, Susan
Publicado 2023

Development of a homogeneous screening assay for automated detection of antiviral agents active against severe acute respiratory syndrome-associated coronavirus

por Ivens, Tania, Eynde, Christel Van den, Acker, Koen Van, Nijs, Erik, Dams, Géry, Bettens, Eva, Ohagen, Asa, Pauwels, Rudi, Hertogs, Kurt
Publicado 2005

Polymorphism of brain derived neurotrophic factor influences β amyloid load in cognitively intact apolipoprotein E ε4 carriers()

por Adamczuk, Katarzyna, De Weer, An-Sofie, Nelissen, Natalie, Chen, Kewei, Sleegers, Kristel, Bettens, Karolien, Van Broeckhoven, Christine, Vandenbulcke, Mathieu, Thiyyagura, Pradeep, Dupont, Patrick, Van Laere, Koen, Reiman, Eric M., Vandenberghe, Rik
Publicado 2013

Reduced secreted clusterin as a mechanism for Alzheimer-associated CLU mutations

por Bettens, Karolien, Vermeulen, Steven, Van Cauwenberghe, Caroline, Heeman, Bavo, Asselbergh, Bob, Robberecht, Caroline, Engelborghs, Sebastiaan, Vandenbulcke, Mathieu, Vandenberghe, Rik, De Deyn, Peter Paul, Cruts, Marc, Van Broeckhoven, Christine, Sleegers, Kristel
Publicado 2015

Alzheimer risk associated with a copy number variation in the complement receptor 1 increasing C3b/C4b binding sites

por Brouwers, N, Van Cauwenberghe, C, Engelborghs, S, Lambert, J-C, Bettens, K, Le Bastard, N, Pasquier, F, Montoya, A Gil, Peeters, K, Mattheijssens, M, Vandenberghe, R, De Deyn, P P, Cruts, M, Amouyel, P, Sleegers, K, Van Broeckhoven, C
Publicado 2012

Both common variations and rare non-synonymous substitutions and small insertion/deletions in CLU are associated with increased Alzheimer risk

por Bettens, Karolien, Brouwers, Nathalie, Engelborghs, Sebastiaan, Lambert, Jean-Charles, Rogaeva, Ekaterina, Vandenberghe, Rik, Le Bastard, Nathalie, Pasquier, Florence, Vermeulen, Steven, Van Dongen, Jasper, Mattheijssens, Maria, Peeters, Karin, Mayeux, Richard, St George-Hyslop, Peter, Amouyel, Philippe, De Deyn, Peter P, Sleegers, Kristel, Van Broeckhoven, Christine
Publicado 2012

A comprehensive study of the genetic impact of rare variants in SORL1 in European early-onset Alzheimer’s disease

por Verheijen, Jan, Van den Bossche, Tobi, van der Zee, Julie, Engelborghs, Sebastiaan, Sanchez-Valle, Raquel, Lladó, Albert, Graff, Caroline, Thonberg, Håkan, Pastor, Pau, Ortega-Cubero, Sara, Pastor, Maria A., Benussi, Luisa, Ghidoni, Roberta, Binetti, Giuliano, Clarimon, Jordi, Lleó, Alberto, Fortea, Juan, de Mendonça, Alexandre, Martins, Madalena, Grau-Rivera, Oriol, Gelpi, Ellen, Bettens, Karolien, Mateiu, Ligia, Dillen, Lubina, Cras, Patrick, De Deyn, Peter P., Van Broeckhoven, Christine, Sleegers, Kristel
Publicado 2016

Genome-wide haplotype association study identifies the FRMD4A gene as a risk locus for Alzheimer's disease

por Lambert, J-C, Grenier-Boley, B, Harold, D, Zelenika, D, Chouraki, V, Kamatani, Y, Sleegers, K, Ikram, M A, Hiltunen, M, Reitz, C, Mateo, I, Feulner, T, Bullido, M, Galimberti, D, Concari, L, Alvarez, V, Sims, R, Gerrish, A, Chapman, J, Deniz-Naranjo, C, Solfrizzi, V, Sorbi, S, Arosio, B, Spalletta, G, Siciliano, G, Epelbaum, J, Hannequin, D, Dartigues, J-F, Tzourio, C, Berr, C, Schrijvers, E M C, Rogers, R, Tosto, G, Pasquier, F, Bettens, K, Van Cauwenberghe, C, Fratiglioni, L, Graff, C, Delepine, M, Ferri, R, Reynolds, C A, Lannfelt, L, Ingelsson, M, Prince, J A, Chillotti, C, Pilotto, A, Seripa, D, Boland, A, Mancuso, M, Bossù, P, Annoni, G, Nacmias, B, Bosco, P, Panza, F, Sanchez-Garcia, F, Del Zompo, M, Coto, E, Owen, M, O'Donovan, M, Valdivieso, F, Caffara, P, Scarpini, E, Combarros, O, Buée, L, Campion, D, Soininen, H, Breteler, M, Riemenschneider, M, Van Broeckhoven, C, Alpérovitch, A, Lathrop, M, Trégouët, D-A, Williams, J, Amouyel, P
Publicado 2013

Genome-wide haplotype association study identifies the FRMD4A gene as a risk locus for Alzheimer's disease

por Lambert, J-C, Grenier-Boley, B, Harold, D, Zelenika, D, Chouraki, V, Kamatani, Y, Sleegers, K, Ikram, M A, Hiltunen, M, Reitz, C, Mateo, I, Feulner, T, Bullido, M, Galimberti, D, Concari, L, Alvarez, V, Sims, R, Gerrish, A, Chapman, J, Deniz-Naranjo, C, Solfrizzi, V, Sorbi, S, Arosio, B, Spalletta, G, Siciliano, G, Epelbaum, J, Hannequin, D, Dartigues, J-F, Tzourio, C, Berr, C, Schrijvers, E M C, Rogers, R, Tosto, G, Pasquier, F, Bettens, K, Van Cauwenberghe, C, Fratiglioni, L, Graff, C, Delepine, M, Ferri, R, Reynolds, C A, Lannfelt, L, Ingelsson, M, Prince, J A, Chillotti, C, Pilotto, A, Seripa, D, Boland, A, Mancuso, M, Bossù, P, Annoni, G, Nacmias, B, Bosco, P, Panza, F, Sanchez-Garcia, F, Zompo, M Del, Coto, E, Owen, M, O'Donovan, M, Valdivieso, F, Caffara, P, Scarpini, E, Combarros, O, Buée, L, Campion, D, Soininen, H, Breteler, M, Riemenschneider, M, Van Broeckhoven, C, Alpérovitch, A, Lathrop, M, Trégouët, D-A, Williams, J, Amouyel, P
Publicado 2013

Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease, and shows evidence for additional susceptibility genes

por Harold, Denise, Abraham, Richard, Hollingworth, Paul, Sims, Rebecca, Gerrish, Amy, Hamshere, Marian, Singh Pahwa, Jaspreet, Moskvina, Valentina, Dowzell, Kimberley, Williams, Amy, Jones, Nicola, Thomas, Charlene, Stretton, Alexandra, Morgan, Angharad, Lovestone, Simon, Powell, John, Proitsi, Petroula, Lupton, Michelle K, Brayne, Carol, Rubinsztein, David C., Gill, Michael, Lawlor, Brian, Lynch, Aoibhinn, Morgan, Kevin, Brown, Kristelle, Passmore, Peter, Craig, David, McGuinness, Bernadette, Todd, Stephen, Holmes, Clive, Mann, David, Smith, A. David, Love, Seth, Kehoe, Patrick G., Hardy, John, Mead, Simon, Fox, Nick, Rossor, Martin, Collinge, John, Maier, Wolfgang, Jessen, Frank, Schürmann, Britta, van den Bussche, Hendrik, Heuser, Isabella, Kornhuber, Johannes, Wiltfang, Jens, Dichgans, Martin, Frölich, Lutz, Hampel, Harald, Hüll, Michael, Rujescu, Dan, Goate, Alison, Kauwe, John S.K., Cruchaga, Carlos, Nowotny, Petra, Morris, John C., Mayo, Kevin, Sleegers, Kristel, Bettens, Karolien, Engelborghs, Sebastiaan, De Deyn, Peter, van Broeckhoven, Christine, Livingston, Gill, Bass, Nicholas J., Gurling, Hugh, McQuillin, Andrew, Gwilliam, Rhian, Deloukas, Panagiotis, Al-Chalabi, Ammar, Shaw, Christopher E., Tsolaki, Magda, Singleton, Andrew, Guerreiro, Rita, Mühleisen, Thomas W., Nöthen, Markus M., Moebus, Susanne, Jöckel, Karl-Heinz, Klopp, Norman, Wichmann, H-Erich, Carrasquillo, Minerva M., Pankratz, V. Shane, Younkin, Steven G., Holmans, Peter, O'Donovan, Michael, Owen, Michael J., Williams, Julie
Publicado 2009