Mammary Gland Involution Provides a Unique Model to Study the TGF-β Cancer Paradox

por Guo, Qiuchen, Betts, Courtney, Pennock, Nathan, Mitchell, Elizabeth, Schedin, Pepper
Publicado 2017

Quantitative Spatial Profiling of Immune Populations in Pancreatic Ductal Adenocarcinoma Reveals Tumor Microenvironment Heterogeneity and Prognostic Biomarkers

por Mi, Haoyang, Sivagnanam, Shamilene, Betts, Courtney B., Liudahl, Shannon M., Jaffee, Elizabeth M., Coussens, Lisa M., Popel, Aleksander S.
Publicado 2022

Ibuprofen supports macrophage differentiation, T cell recruitment, and tumor suppression in a model of postpartum breast cancer

por Pennock, Nathan D., Martinson, Holly A., Guo, Qiuchen, Betts, Courtney B., Jindal, Sonali, Tsujikawa, Takahiro, Coussens, Lisa M., Borges, Virginia F., Schedin, Pepper
Publicado 2018

High IRF8 expression correlates with CD8 T cell infiltration and is a predictive biomarker of therapy response in ER-negative breast cancer

por Gatti, Gerardo, Betts, Courtney, Rocha, Darío, Nicola, Maribel, Grupe, Verónica, Ditada, Cecilia, Nuñez, Nicolas G., Roselli, Emiliano, Araya, Paula, Dutto, Jeremías, Boffelli, Lucia, Fernández, Elmer, Coussens, Lisa M., Maccioni, Mariana
Publicado 2021

Correction to: High IRF8 expression correlates with CD8 T cell infiltration and is a predictive biomarker of therapy response in ER-negative breast cancer

por Gatti, Gerardo, Betts, Courtney, Rocha, Darío, Nicola, Maribel, Grupe, Verónica, Ditada, Cecilia, Nuñez, Nicolas G., Roselli, Emiliano, Araya, Paula, Dutto, Jeremías, Boffelli, Lucia, Fernández, Elmer, Coussens, Lisa M., Maccioni, Mariana
Publicado 2021

A Cancer Cell–Intrinsic GOT2–PPARδ Axis Suppresses Antitumor Immunity

por Abrego, Jaime, Sanford-Crane, Hannah, Oon, Chet, Xiao, Xu, Betts, Courtney B., Sun, Duanchen, Nagarajan, Shanthi, Diaz, Luis, Sandborg, Holly, Bhattacharyya, Sohinee, Xia, Zheng, Coussens, Lisa M., Tontonoz, Peter, Sherman, Mara H.
Publicado 2022

Machine learning links T cell function and spatial localization to neoadjuvant immunotherapy and clinical outcome in pancreatic cancer

por Blise, Katie E., Sivagnanam, Shamilene, Betts, Courtney B., Betre, Konjit, Kirchberger, Nell, Tate, Benjamin, Furth, Emma E., Dias Costa, Andressa, Nowak, Jonathan A., Wolpin, Brian M., Vonderheide, Robert H., Goecks, Jeremy, Coussens, Lisa M., Byrne, Katelyn T.
Publicado 2023

Therapeutics That Promote Sympathetic Reinnervation Modulate the Inflammatory Response After Myocardial Infarction

por Sepe, Joseph J., Gardner, Ryan T., Blake, Matthew R., Brooks, Deja M., Staffenson, Melanie A., Betts, Courtney B., Sivagnanam, Sam, Larson, William, Kumar, Sushil, Bayles, Richard G., Jin, Haihong, Cohen, Michael S., Coussens, Lisa M., Habecker, Beth A.
Publicado 2022

Safety and Efficacy of Pembrolizumab in Combination with Acalabrutinib in Advanced Head and Neck Squamous Cell Carcinoma: Phase 2 Proof-of-Concept Study

por Taylor, Matthew H., Betts, Courtney B., Maloney, Lauren, Nadler, Eric, Algazi, Alain, Guarino, Michael J., Nemunaitis, John, Jimeno, Antonio, Patel, Priti, Munugalavadla, Veerendra, Tao, Lin, Adkins, Douglas, Goldschmidt, Jerome H., Cohen, Ezra E.W., Coussens, Lisa M.
Publicado 2022

Tumor-Infiltrating Leukocyte Phenotypes Distinguish Outcomes in Related Patients With Pancreatic Adenocarcinoma

por Link, Jason M., Liudahl, Shannon M., Betts, Courtney B., Sivagnanam, Shamilene, Leis, Kenna R., McDonnell, Mary, Pelz, Carl R., Johnson, Brett, Hamman, Kelly J., Keith, Dove, Sampson, Jone E., Morgan, Terry K., Lopez, Charles D., Coussens, Lisa M., Sears, Rosalie C.
Publicado 2021

Modulation of myeloid and T cells in vivo by Bruton’s tyrosine kinase inhibitor ibrutinib in patients with metastatic pancreatic ductal adenocarcinoma

por Sinha, Meenal, Betts, Courtney, Zhang, Li, Griffith, Madeline J, Solman, Isabelle, Chen, Brandon, Liu, Eric, Tamaki, Whitney, Stultz, Jacob, Marquez, Jaqueline, Sivagnanam, Shamilene, Cheung, Alexander, Pener, Denise, Fahlman, Anne, Taber, Erin, Lerner, Kimberly, Crocker, Matthew, Todd, Kendra, Rajagopalan, Brindha, Ware, Clarisha, Bridge, Mark, Vo, Johnson, Dragomanovich, Hannah, Sudduth-Klinger, Julie, Vaccaro, Gina, Lopez, Charles D, Tempero, Margaret, Coussens, Lisa M, Fong, Lawrence
Publicado 2023

Multiomics analysis of serial PARP inhibitor treated metastatic TNBC inform on rational combination therapies

por Labrie, Marilyne, Li, Allen, Creason, Allison, Betts, Courtney, Keck, Jamie, Johnson, Brett, Sivagnanam, Shamilene, Boniface, Christopher, Ma, Hongli, Blucher, Aurora, Chang, Young Hwan, Chin, Koei, Vuky, Jacqueline, Guimaraes, Alexander R., Downey, Molly, Lim, Jeong Youn, Gao, Lina, Siex, Kiara, Parmar, Swapnil, Kolodzie, Annette, Spellman, Paul T., Goecks, Jeremy, Coussens, Lisa M., Corless, Christopher L., Bergan, Raymond, Gray, Joe W., Mills, Gordon B., Mitri, Zahi I.
Publicado 2021

MCMICRO: a scalable, modular image-processing pipeline for multiplexed tissue imaging

por Schapiro, Denis, Sokolov, Artem, Yapp, Clarence, Chen, Yu-An, Muhlich, Jeremy L., Hess, Joshua, Creason, Allison L., Nirmal, Ajit J., Baker, Gregory J., Nariya, Maulik K., Lin, Jia-Ren, Maliga, Zoltan, Jacobson, Connor A., Hodgman, Matthew W., Ruokonen, Juha, Farhi, Samouil L., Abbondanza, Domenic, McKinley, Eliot T., Persson, Daniel, Betts, Courtney, Sivagnanam, Shamilene, Regev, Aviv, Goecks, Jeremy, Coffey, Robert J., Coussens, Lisa M., Santagata, Sandro, Sorger, Peter K.
Publicado 2021

MYC Deregulation and PTEN Loss Model Tumor and Stromal Heterogeneity of Aggressive Triple-Negative Breast Cancer

por Doha, Zinab O., Wang, Xiaoyan, Calistri, Nicholas L., Eng, Jennifer, Daniel, Colin J., Ternes, Luke, Kim, Eun Na, Pelz, Carl, Munks, Michael, Betts, Courtney, Kwon, Sunjong, Bucher, Elmar, Li, Xi, Waugh, Trent, Tatarova, Zuzana, Blumberg, Dylan, Ko, Aaron, Kirchberger, Nell, Pietenpol, Jennifer A., Sanders, Melinda E., Langer, Ellen M., Dai, Mu-Shui, Mills, Gordon, Chin, Koei, Chang, Young Hwan, Coussens, Lisa M., Gray, Joe W., Heiser, Laura M., Sears, Rosalie C.
Publicado 2023

Neoadjuvant Selicrelumab, an Agonist CD40 Antibody, Induces Changes in the Tumor Microenvironment in Patients with Resectable Pancreatic Cancer

por Byrne, Katelyn T., Betts, Courtney B., Mick, Rosemarie, Sivagnanam, Shamilene, Bajor, David L., Laheru, Daniel A., Chiorean, E. Gabriela, O'Hara, Mark H., Liudahl, Shannon M., Newcomb, Craig, Alanio, Cécile, Ferreira, Ana P., Park, Byung S., Ohtani, Takuya, Huffman, Austin P., Väyrynen, Sara A., Dias Costa, Andressa, Kaiser, Judith C., Lacroix, Andreanne M., Redlinger, Colleen, Stern, Martin, Nowak, Jonathan A., Wherry, E. John, Cheever, Martin A., Wolpin, Brian M., Furth, Emma E., Jaffee, Elizabeth M., Coussens, Lisa M., Vonderheide, Robert H.
Publicado 2021

An omic and multidimensional spatial atlas from serial biopsies of an evolving metastatic breast cancer

por Johnson, Brett E., Creason, Allison L., Stommel, Jayne M., Keck, Jamie M., Parmar, Swapnil, Betts, Courtney B., Blucher, Aurora, Boniface, Christopher, Bucher, Elmar, Burlingame, Erik, Camp, Todd, Chin, Koei, Eng, Jennifer, Estabrook, Joseph, Feiler, Heidi S., Heskett, Michael B., Hu, Zhi, Kolodzie, Annette, Kong, Ben L., Labrie, Marilyne, Lee, Jinho, Leyshock, Patrick, Mitri, Souraya, Patterson, Janice, Riesterer, Jessica L., Sivagnanam, Shamilene, Somers, Julia, Sudar, Damir, Thibault, Guillaume, Weeder, Benjamin R., Zheng, Christina, Nan, Xiaolin, Thompson, Reid F., Heiser, Laura M., Spellman, Paul T., Thomas, George, Demir, Emek, Chang, Young Hwan, Coussens, Lisa M., Guimaraes, Alexander R., Corless, Christopher, Goecks, Jeremy, Bergan, Raymond, Mitri, Zahi, Mills, Gordon B., Gray, Joe W.
Publicado 2022