Anatolicin, a Highly Potent and Selective Cytotoxic Sesquiterpene Coumarin from the Root Extract of Heptaptera anatolica

por Tosun, Fatma, Beutler, John A., Ransom, Tanya T., Miski, Mahmut
Publicado 2019

Neopapillarine, an Unusual Coumarino-Alkaloid from the Root Extract of Neocryptodiscus papillaris with Cytotoxic Activity on Renal Cancer Cells

por Tosun, Fatma, Mıhoğlugil, Feyyaz, Beutler, John A., Eroğlu Özkan, Esra, Miski, Mahmut
Publicado 2020

Synthesis of a Coumarin-Based Analogue of Schweinfurthin F

por Schroeder, Chloe M., Dey, Patrick N., Beutler, John A., Wiemer, David F.
Publicado 2021

Identification of Four Potential Epigenetic Modulators from the NCI Structural Diversity Library Using a Cell-Based Assay

por Best, Anne M., Chang, Jianjun, Dull, Angie B., Beutler, John A., Martinez, Elisabeth D.
Publicado 2011

Stilbenes as κ-Selective, Non-nitrogenous Opioid Receptor Antagonists

por Hartung, Alyssa M., Beutler, John A., Navarro, Hernán A., Wiemer, David F., Neighbors, Jeffrey D.
Publicado 2014

Synthesis and Biological Evaluation of New (−)‐Englerin Analogues

por López‐Suárez, Laura, Riesgo, Lorena, Bravo, Fernando, Ransom, Tanya T., Beutler, John A., Echavarren, Antonio M.
Publicado 2016

Inhibition of Nitric Oxide Production in BV2 Microglial Cells by Triterpenes from Tetrapanax papyriferus

por Cho, Namki, Moon, Eun Hye, Kim, Hyun Woo, Hong, Jaewoo, Beutler, John A., Sung, Sang Hyun
Publicado 2016

Preparative Purification of Anti-Proliferative Diarylheptanoids from Betula platyphylla by High-Speed Counter-Current Chromatography

por Cho, Namki, Kim, Hyun Woo, Kim, Tae Bum, Ransom, Tanya T., Beutler, John A., Sung, Sang Hyun
Publicado 2016

Bioactive Cembranoids from the South China Sea Soft Coral Sarcophyton elegans

por Liu, Xin, Zhang, Junsheng, Liu, Qiao, Tang, Guihua, Wang, Hongsheng, Fan, Chengqi, Yin, Sheng, Beutler, John
Publicado 2015

Novel Cytotoxic Sesquiterpene Coumarin Ethers and Sulfur-Containing Compounds from the Roots of Ferula turcica

por Eruçar, Fatma Memnune, Senadeera, Sarath P. D., Wilson, Jennifer A., Goncharova, Ekaterina, Beutler, John A., Miski, Mahmut
Publicado 2023

Steroidal Alkaloids from the Marine Sponge Corticium niger That Inhibit Growth of Human Colon Carcinoma Cells

por Sunassee, Suthananda N., Ransom, Tanya, Henrich, Curtis J., Beutler, John A., Covell, David G., McMahon, James B., Gustafson, Kirk R.
Publicado 2014

Two distinct modes of metal ion binding in the nuclease active site of a viral DNA-packaging terminase: insight into the two-metal-ion catalytic mechanism

por Zhao, Haiyan, Lin, Zihan, Lynn, Anna Y., Varnado, Brittany, Beutler, John A., Murelli, Ryan P., Le Grice, Stuart F. J., Tang, Liang
Publicado 2015

Tonantzitlolone cytotoxicity toward renal cancer cells is PKCθ- and HSF1-dependent

por Sourbier, Carole, Scroggins, Bradley T., Mannes, Philip Z., Liao, Pei-Jyun, Siems, Karsten, Wolf, Dietmar, Beutler, John A., Linehan, W. Marston, Neckers, Leonard
Publicado 2015

Cytotoxic Triterpenes from Salacia crassifolia and Metabolite Profiling of Celastraceae Species

por Espindola, Laila S., Dusi, Renata G., Demarque, Daniel P., Braz-Filho, Raimundo, Yan, Pengcheng, Bokesch, Heidi R., Gustafson, Kirk R., Beutler, John A.
Publicado 2018

Scaffold hopping and optimisation of 3’,4’-dihydroxyphenyl- containing thienopyrimidinones: synthesis of quinazolinone derivatives as novel allosteric inhibitors of HIV-1 reverse t...

por Tocco, Graziella, Esposito, Francesca, Caboni, Pierluigi, Laus, Antonio, Beutler, John A., Wilson, Jennifer A., Corona, Angela, Le Grice, Stuart F. J., Tramontano, Enzo
Publicado 2020

A Molecular Networking Strategy: High-Throughput Screening and Chemical Analysis of Brazilian Cerrado Plant Extracts against Cancer Cells

por Cortelo, Patrícia C., Demarque, Daniel P., Dusi, Renata G., Albernaz, Lorena C., Braz-Filho, Raimundo, Goncharova, Ekaterina I., Bokesch, Heidi R., Gustafson, Kirk R., Beutler, John A., Espindola, Laila S.
Publicado 2021

Selective inhibition of HIV-1 reverse transcriptase-associated ribonuclease H activity by hydroxylated tropolones

por Budihas, Scott R., Gorshkova, Inna, Gaidamakov, Sergei, Wamiru, Antony, Bona, Marion K., Parniak, Michael A., Crouch, Robert J., McMahon, James B., Beutler, John A., Le Grice, Stuart F. J.
Publicado 2005