Blood‐derived DNA methylation predictors of mortality discriminate tumor and healthy tissue in multiple organs

por Zhang, Yan, Bewerunge‐Hudler, Melanie, Schick, Matthias, Burwinkel, Barbara, Herpel, Esther, Hoffmeister, Michael, Brenner, Hermann
Publicado 2020

DNA Methylation-Based Estimates of Circulating Leukocyte Composition for Predicting Colorectal Cancer Survival: A Prospective Cohort Study

por Gào, Xīn, Zhang, Yan, Li, Xiangwei, Jansen, Lina, Alwers, Elizabeth, Bewerunge-Hudler, Melanie, Schick, Matthias, Chang-Claude, Jenny, Hoffmeister, Michael, Brenner, Hermann
Publicado 2021

Systematic screening of isogenic cancer cells identifies DUSP6 as context-specific synthetic lethal target in melanoma

por Wittig-Blaich, Stephanie, Wittig, Rainer, Schmidt, Steffen, Lyer, Stefan, Bewerunge-Hudler, Melanie, Gronert-Sum, Sabine, Strobel-Freidekind, Olga, Müller, Carolin, List, Markus, Jaskot, Aleksandra, Christiansen, Helle, Hafner, Mathias, Schadendorf, Dirk, Block, Ines, Mollenhauer, Jan
Publicado 2017

A prognostic CpG score derived from epigenome-wide profiling of tumor tissue was independently associated with colorectal cancer survival

por Jia, Min, Zhang, Yan, Jansen, Lina, Walter, Viola, Edelmann, Dominic, Gündert, Melanie, Tagscherer, Katrin E., Roth, Wilfried, Bewerunge-Hudler, Melanie, Herpel, Esther, Kloor, Matthias, Ulrich, Alexis, Burwinkel, Barbara, Bläker, Hendrik, Chang-Claude, Jenny, Brenner, Hermann, Hoffmeister, Michael
Publicado 2019

Profiling of gallbladder carcinoma reveals distinct miRNA profiles and activation of STAT1 by the tumor suppressive miRNA-145-5p

por Goeppert, Benjamin, Truckenmueller, Felicia, Ori, Alessandro, Fritz, Valerie, Albrecht, Thomas, Fraas, Angelika, Scherer, Dominique, Silos, Rosa González, Sticht, Carsten, Gretz, Norbert, Mehrabi, Arianeb, Bewerunge-Hudler, Melanie, Pusch, Stefan, Bermejo, Justo Lorenzo, Dietrich, Peter, Schirmacher, Peter, Renner, Marcus, Roessler, Stephanie
Publicado 2019

Robust molecular subgrouping and copy-number profiling of medulloblastoma from small amounts of archival tumour material using high-density DNA methylation arrays

por Hovestadt, Volker, Remke, Marc, Kool, Marcel, Pietsch, Torsten, Northcott, Paul A., Fischer, Roger, Cavalli, Florence M. G., Ramaswamy, Vijay, Zapatka, Marc, Reifenberger, Guido, Rutkowski, Stefan, Schick, Matthias, Bewerunge-Hudler, Melanie, Korshunov, Andrey, Lichter, Peter, Taylor, Michael D., Pfister, Stefan M., Jones, David T. W.
Publicado 2013

Genome-wide methylation profiling and copy number analysis in atypical fibroxanthomas and pleomorphic dermal sarcomas indicate a similar molecular phenotype

por Koelsche, Christian, Stichel, Damian, Griewank, Klaus G., Schrimpf, Daniel, Reuss, David E., Bewerunge-Hudler, Melanie, Vokuhl, Christian, Dinjens, Winand N. M., Petersen, Iver, Mittelbronn, Michel, Cuevas-Bourdier, Adrian, Buslei, Rolf, Pfister, Stefan M., Flucke, Uta, Mechtersheimer, Gunhild, Mentzel, Thomas, von Deimling, Andreas
Publicado 2019

DNA methylation array analysis identifies breast cancer associated RPTOR, MGRN1 and RAPSN hypomethylation in peripheral blood DNA

por Tang, Qiuqiong, Holland-Letz, Tim, Slynko, Alla, Cuk, Katarina, Marme, Frederik, Schott, Sarah, Heil, Jörg, Qu, Bin, Golatta, Michael, Bewerunge-Hudler, Melanie, Sutter, Christian, Surowy, Harald, Wappenschmidt, Barbara, Schmutzler, Rita, Hoth, Markus, Bugert, Peter, Bartram, Claus R., Sohn, Christof, Schneeweiss, Andreas, Yang, Rongxi, Burwinkel, Barbara
Publicado 2016

DNA-methylome-assisted classification of patients with poor prognostic subventricular zone associated IDH-wildtype glioblastoma

por Adeberg, Sebastian, Knoll, Maximilian, Koelsche, Christian, Bernhardt, Denise, Schrimpf, Daniel, Sahm, Felix, König, Laila, Harrabi, Semi Ben, Hörner-Rieber, Juliane, Verma, Vivek, Bewerunge-Hudler, Melanie, Unterberg, Andreas, Sturm, Dominik, Jungk, Christine, Herold-Mende, Christel, Wick, Wolfgang, von Deimling, Andreas, Debus, Juergen, Rieken, Stefan, Abdollahi, Amir
Publicado 2022

MEST mediates the impact of prenatal bisphenol A exposure on long-term body weight development

por Junge, Kristin M., Leppert, Beate, Jahreis, Susanne, Wissenbach, Dirk K., Feltens, Ralph, Grützmann, Konrad, Thürmann, Loreen, Bauer, Tobias, Ishaque, Naveed, Schick, Matthias, Bewerunge-Hudler, Melanie, Röder, Stefan, Bauer, Mario, Schulz, Angela, Borte, Michael, Landgraf, Kathrin, Körner, Antje, Kiess, Wieland, von Bergen, Martin, Stangl, Gabriele I., Trump, Saskia, Eils, Roland, Polte, Tobias, Lehmann, Irina
Publicado 2018

Histone 3.3 hotspot mutations in conventional osteosarcomas: a comprehensive clinical and molecular characterization of six H3F3A mutated cases

por Koelsche, Christian, Schrimpf, Daniel, Tharun, Lars, Roth, Eva, Sturm, Dominik, Jones, David T. W., Renker, Eva-Kristin, Sill, Martin, Baude, Annika, Sahm, Felix, Capper, David, Bewerunge-Hudler, Melanie, Hartmann, Wolfgang, Kulozik, Andreas E., Petersen, Iver, Flucke, Uta, Schreuder, Hendrik W. B., Büttner, Reinhard, Weber, Marc-André, Schirmacher, Peter, Plass, Christoph, Pfister, Stefan M., von Deimling, Andreas, Mechtersheimer, Gunhild
Publicado 2017

A complementary study approach unravels novel players in the pathoetiology of Hirschsprung disease

por Mederer, Tanja, Schmitteckert, Stefanie, Volz, Julia, Martínez, Cristina, Röth, Ralph, Thumberger, Thomas, Eckstein, Volker, Scheuerer, Jutta, Thöni, Cornelia, Lasitschka, Felix, Carstensen, Leonie, Günther, Patrick, Holland-Cunz, Stefan, Hofstra, Robert, Brosens, Erwin, Rosenfeld, Jill A., Schaaf, Christian P., Schriemer, Duco, Ceccherini, Isabella, Rusmini, Marta, Tilghman, Joseph, Luzón-Toro, Berta, Torroglosa, Ana, Borrego, Salud, Sze-man Tang, Clara, Garcia-Barceló, Mercè, Tam, Paul, Paramasivam, Nagarajan, Bewerunge-Hudler, Melanie, De La Torre, Carolina, Gretz, Norbert, Rappold, Gudrun A., Romero, Philipp, Niesler, Beate
Publicado 2020

Integrated Molecular-Morphologic Meningioma Classification: A Multicenter Retrospective Analysis, Retrospectively and Prospectively Validated

por Maas, Sybren L. N., Stichel, Damian, Hielscher, Thomas, Sievers, Philipp, Berghoff, Anna S., Schrimpf, Daniel, Sill, Martin, Euskirchen, Philipp, Blume, Christina, Patel, Areeba, Dogan, Helin, Reuss, David, Dohmen, Hildegard, Stein, Marco, Reinhardt, Annekathrin, Suwala, Abigail K., Wefers, Annika K., Baumgarten, Peter, Ricklefs, Franz, Rushing, Elisabeth J., Bewerunge-Hudler, Melanie, Ketter, Ralf, Schittenhelm, Jens, Jaunmuktane, Zane, Leu, Severina, Greenway, Fay E. A., Bridges, Leslie R., Jones, Timothy, Grady, Conor, Serrano, Jonathan, Golfinos, John, Sen, Chandra, Mawrin, Christian, Jungk, Christine, Hänggi, Daniel, Westphal, Manfred, Lamszus, Katrin, Etminan, Nima, Jungwirth, Gerhard, Herold-Mende, Christel, Unterberg, Andreas, Harter, Patrick N., Wirsching, Hans-Georg, Neidert, Marian C., Ratliff, Miriam, Platten, Michael, Snuderl, Matija, Aldape, Kenneth D., Brandner, Sebastian, Hench, Jürgen, Frank, Stephan, Pfister, Stefan M., Jones, David T. W., Reifenberger, Guido, Acker, Till, Wick, Wolfgang, Weller, Michael, Preusser, Matthias, von Deimling, Andreas, Sahm, Felix
Publicado 2021

Sarcoma classification by DNA methylation profiling

por Koelsche, Christian, Schrimpf, Daniel, Stichel, Damian, Sill, Martin, Sahm, Felix, Reuss, David E., Blattner, Mirjam, Worst, Barbara, Heilig, Christoph E., Beck, Katja, Horak, Peter, Kreutzfeldt, Simon, Paff, Elke, Stark, Sebastian, Johann, Pascal, Selt, Florian, Ecker, Jonas, Sturm, Dominik, Pajtler, Kristian W., Reinhardt, Annekathrin, Wefers, Annika K., Sievers, Philipp, Ebrahimi, Azadeh, Suwala, Abigail, Fernández-Klett, Francisco, Casalini, Belén, Korshunov, Andrey, Hovestadt, Volker, Kommoss, Felix K. F., Kriegsmann, Mark, Schick, Matthias, Bewerunge-Hudler, Melanie, Milde, Till, Witt, Olaf, Kulozik, Andreas E., Kool, Marcel, Romero-Pérez, Laura, Grünewald, Thomas G. P., Kirchner, Thomas, Wick, Wolfgang, Platten, Michael, Unterberg, Andreas, Uhl, Matthias, Abdollahi, Amir, Debus, Jürgen, Lehner, Burkhard, Thomas, Christian, Hasselblatt, Martin, Paulus, Werner, Hartmann, Christian, Staszewski, Ori, Prinz, Marco, Hench, Jürgen, Frank, Stephan, Versleijen-Jonkers, Yvonne M. H., Weidema, Marije E., Mentzel, Thomas, Griewank, Klaus, de Álava, Enrique, Martín, Juan Díaz, Gastearena, Miguel A. Idoate, Chang, Kenneth Tou-En, Low, Sharon Yin Yee, Cuevas-Bourdier, Adrian, Mittelbronn, Michel, Mynarek, Martin, Rutkowski, Stefan, Schüller, Ulrich, Mautner, Viktor F., Schittenhelm, Jens, Serrano, Jonathan, Snuderl, Matija, Büttner, Reinhard, Klingebiel, Thomas, Buslei, Rolf, Gessler, Manfred, Wesseling, Pieter, Dinjens, Winand N. M., Brandner, Sebastian, Jaunmuktane, Zane, Lyskjær, Iben, Schirmacher, Peter, Stenzinger, Albrecht, Brors, Benedikt, Glimm, Hanno, Heining, Christoph, Tirado, Oscar M., Sáinz-Jaspeado, Miguel, Mora, Jaume, Alonso, Javier, del Muro, Xavier Garcia, Moran, Sebastian, Esteller, Manel, Benhamida, Jamal K., Ladanyi, Marc, Wardelmann, Eva, Antonescu, Cristina, Flanagan, Adrienne, Dirksen, Uta, Hohenberger, Peter, Baumhoer, Daniel, Hartmann, Wolfgang, Vokuhl, Christian, Flucke, Uta, Petersen, Iver, Mechtersheimer, Gunhild, Capper, David, Jones, David T. W., Fröhling, Stefan, Pfister, Stefan M., von Deimling, Andreas
Publicado 2021

DNA methylation-based classification of central nervous system tumours

por Capper, David, Jones, David T.W., Sill, Martin, Hovestadt, Volker, Schrimpf, Daniel, Sturm, Dominik, Koelsche, Christian, Sahm, Felix, Chavez, Lukas, Reuss, David E., Kratz, Annekathrin, Wefers, Annika K., Huang, Kristin, Pajtler, Kristian W., Schweizer, Leonille, Stichel, Damian, Olar, Adriana, Engel, Nils W., Lindenberg, Kerstin, Harter, Patrick N., Braczynski, Anne, Plate, Karl H., Dohmen, Hildegard, Garvalov, Boyan K., Coras, Roland, Hölsken, Annett, Hewer, Ekkehard, Bewerunge-Hudler, Melanie, Schick, Matthias, Fischer, Roger, Beschorner, Rudi, Schittenhelm, Jens, Staszewski, Ori, Wani, Khalida, Varlet, Pascale, Pages, Melanie, Temming, Petra, Lohmann, Dietmar, Selt, Florian, Witt, Hendrik, Milde, Till, Witt, Olaf, Aronica, Eleonora, Giangaspero, Felice, Rushing, Elisabeth, Scheurlen, Wolfram, Geisenberger, Christoph, Rodriguez, Fausto J., Becker, Albert, Preusser, Matthias, Haberler, Christine, Bjerkvig, Rolf, Cryan, Jane, Farrell, Michael, Deckert, Martina, Hench, Jürgen, Frank, Stephan, Serrano, Jonathan, Kannan, Kasthuri, Tsirigos, Aristotelis, Brück, Wolfgang, Hofer, Silvia, Brehmer, Stefanie, Seiz-Rosenhagen, Marcel, Hänggi, Daniel, Hans, Volkmar, Rozsnoki, Stephanie, Hansford, Jordan R., Kohlhof, Patricia, Kristensen, Bjarne W., Lechner, Matt, Lopes, Beatriz, Mawrin, Christian, Ketter, Ralf, Kulozik, Andreas, Khatib, Ziad, Heppner, Frank, Koch, Arend, Jouvet, Anne, Keohane, Catherine, Mühleisen, Helmut, Mueller, Wolf, Pohl, Ute, Prinz, Marco, Benner, Axel, Zapatka, Marc, Gottardo, Nicholas G., Driever, Pablo Hernáiz, Kramm, Christof M., Müller, Hermann L., Rutkowski, Stefan, von Hoff, Katja, Frühwald, Michael C., Gnekow, Astrid, Fleischhack, Gudrun, Tippelt, Stephan, Calaminus, Gabriele, Monoranu, Camelia-Maria, Perry, Arie, Jones, Chris, Jacques, Thomas S., Radlwimmer, Bernhard, Gessi, Marco, Pietsch, Torsten, Schramm, Johannes, Schackert, Gabriele, Westphal, Manfred, Reifenberger, Guido, Wesseling, Pieter, Weller, Michael, Collins, Vincent Peter, Blümcke, Ingmar, Bendszus, Martin, Debus, Jürgen, Huang, Annie, Jabado, Nada, Northcott, Paul A., Paulus, Werner, Gajjar, Amar, Robinson, Giles, Taylor, Michael D., Jaunmuktane, Zane, Ryzhova, Marina, Platten, Michael, Unterberg, Andreas, Wick, Wolfgang, Karajannis, Matthias A., Mittelbronn, Michel, Acker, Till, Hartmann, Christian, Aldape, Kenneth, Schüller, Ulrich, Buslei, Rolf, Lichter, Peter, Kool, Marcel, Herold-Mende, Christel, Ellison, David W., Hasselblatt, Martin, Snuderl, Matija, Brandner, Sebastian, Korshunov, Andrey, von Deimling, Andreas, Pfister, Stefan M.
Publicado 2018