Anti-TNF Biologicals Enhance the Anti-Inflammatory Properties of IgG N-Glycome in Crohn’s Disease

por Hanić, Maja, Vučković, Frano, Deriš, Helena, Bewshea, Claire, Lin, Simeng, Goodhand, James R., Ahmad, Tariq, Trbojević-Akmačić, Irena, Kennedy, Nicholas A., Lauc, Gordan, Consortium, PANTS
Publicado 2023

Understanding anti‐TNF treatment failure: does serum triiodothyronine‐to‐thyroxine (T3/T4) ratio predict therapeutic outcome to anti‐TNF therapies in biologic‐naïve patients with a...

por Lin, Simeng, Chanchlani, Neil, Carbery, Isabel, Janjua, Malik, Nice, Rachel, McDonald, Timothy J., Bewshea, Claire, Kennedy, Nicholas A., Ahmad, Tariq, Selinger, Christian P., Goodhand, James R.
Publicado 2022

Pretreatment Vitamin D Concentrations Do Not Predict Therapeutic Outcome to Anti-TNF Therapies in Biologic-Naïve Patients With Active Luminal Crohn’s Disease

por Chanchlani, Neil, Lin, Simeng, Smith, Rebecca, Roberts, Christopher, Nice, Rachel, McDonald, Timothy J, Hamilton, Benjamin, Bishara, Maria, Bewshea, Claire, Kennedy, Nicholas A, Goodhand, James R, Ahmad, Tariq
Publicado 2023

Su1611: POOR RESPONSE TO ANTI-SARS-COV-2 VACCINATION IN IMMUNOSUPPRESSED INFLAMMATORY BOWEL DISEASE PATIENTS IS ASSOCIATED WITH ALTERED GUT MICROBIOTA FUNCTION

por Alexander, James L., Mullish, Benjamin H., Danckert, Nathan P., Liu, Zhigang, Saifuddin, Aamir, Torkizadeh, Melissa, Ibraheim, Hajir, Blanco, Jesús Miguéns, Bewshea, Claire M., Nice, Rachel, Lin, Simeng, Prabhudev, Hemanth, Sands, Caroline, Lewis, Matthew, Teare, Julian P., Hart, Ailsa, Kennedy, Nick, Ahmad, Tariq, Marchesi, Julian, Powell, Nick
Publicado 2022

Neutralising antibody potency against SARS-CoV-2 wild-type and omicron BA.1 and BA.4/5 variants in patients with inflammatory bowel disease treated with infliximab and vedolizumab...

por Liu, Zhigang, Le, Kaixing, Zhou, Xin, Alexander, James L, Lin, Simeng, Bewshea, Claire, Chanchlani, Neil, Nice, Rachel, McDonald, Timothy J, Lamb, Christopher A, Sebastian, Shaji, Kok, Klaartje, Lees, Charlie W, Hart, Ailsa L, Pollok, Richard C, Boyton, Rosemary J, Altmann, Daniel M, Pollock, Katrina M, Goodhand, James R, Kennedy, Nicholas A, Ahmad, Tariq, Powell, Nick
Publicado 2023

Adalimumab and Infliximab Impair SARS-CoV-2 Antibody Responses: Results from a Therapeutic Drug Monitoring Study in 11 422 Biologic-Treated Patients

por Chanchlani, Neil, Lin, Simeng, Chee, Desmond, Hamilton, Benjamin, Nice, Rachel, Arkir, Zehra, Bewshea, Claire, Cipriano, Bessie, Derikx, Lauranne A A P, Dunlop, Allan, Greathead, Louise, Griffiths, Rachel L, Ibraheim, Hajir, Kelleher, Peter, Kok, Klaartje B, Lees, Charlie W, MacDonald, Jonathan, Sebastian, Shaji, Smith, Philip J, McDonald, Timothy J, Irving, Peter M, Powell, Nick, Kennedy, Nicholas A, Goodhand, James R, Ahmad, Tariq
Publicado 2021

Su1485: COVID-19 VACCINE-INDUCED ANTIBODY RESPONSES ARE IMPAIRED IN IBD PATIENTS TREATED WITH INFLIXIMAB, USTEKINUMAB OR TOFACITINIB, BUT NOT THIOPURINES OR VEDOLIZUMAB

por Alexander, James L., Kennedy, Nick, Ibraheim, Hajir, Anandabaskaran, Sulak, Saifuddin, Aamir, Seoane, Rocio Castro, Liu, Zhigang, Nice, Rachel, Bewshea, Claire M., D'Mello, Andrea, Constable, Laura E., Jones, Gareth-Rhys, Balarajah, Sharmili, Fiorentino, Francesca, Sebastian, Shaji, Irving, Peter M., Hicks, Lucy C., Williams, Horace R., Kent, Alexandra J., Parkes, Miles, Kok, Klaartje, Patel, Kamal V, Altmann, Daniel, Boyton, Rosemary, Goodhand, James, Hart, Ailsa, Lees, Charlie W., Ahmad, Tariq, Powell, Nick
Publicado 2022

The gut microbiota and metabolome are associated with diminished COVID-19 vaccine-induced antibody responses in immunosuppressed inflammatory bowel disease patients

por Alexander, James L., Mullish, Benjamin H., Danckert, Nathan P., Liu, Zhigang, Olbei, Marton L., Saifuddin, Aamir, Torkizadeh, Melissa, Ibraheim, Hajir, Blanco, Jesús Miguéns, Roberts, Lauren A., Bewshea, Claire M., Nice, Rachel, Lin, Simeng, Prabhudev, Hemanth, Sands, Caroline, Horneffer-van der Sluis, Verena, Lewis, Matthew, Sebastian, Shaji, Lees, Charlie W., Teare, Julian P., Hart, Ailsa, Goodhand, James R., Kennedy, Nicholas A., Korcsmaros, Tamas, Marchesi, Julian R., Ahmad, Tariq, Powell, Nick
Publicado 2023

COVID-19 vaccine-induced antibody responses in immunosuppressed patients with inflammatory bowel disease (VIP): a multicentre, prospective, case-control study

por Alexander, James L, Kennedy, Nicholas A, Ibraheim, Hajir, Anandabaskaran, Sulak, Saifuddin, Aamir, Castro Seoane, Rocio, Liu, Zhigang, Nice, Rachel, Bewshea, Claire, D'Mello, Andrea, Constable, Laura, Jones, Gareth R, Balarajah, Sharmili, Fiorentino, Francesca, Sebastian, Shaji, Irving, Peter M, Hicks, Lucy C, Williams, Horace R T, Kent, Alexandra J, Linger, Rachel, Parkes, Miles, Kok, Klaartje, Patel, Kamal V, Teare, Julian P, Altmann, Daniel M, Boyton, Rosemary J, Goodhand, James R, Hart, Ailsa L, Lees, Charlie W, Ahmad, Tariq, Powell, Nick
Publicado 2022

Antibody decay, T cell immunity and breakthrough infections following two SARS-CoV-2 vaccine doses in inflammatory bowel disease patients treated with infliximab and vedolizumab

por Lin, Simeng, Kennedy, Nicholas A., Saifuddin, Aamir, Sandoval, Diana Muñoz, Reynolds, Catherine J., Seoane, Rocio Castro, Kottoor, Sherine H., Pieper, Franziska P., Lin, Kai-Min, Butler, David K., Chanchlani, Neil, Nice, Rachel, Chee, Desmond, Bewshea, Claire, Janjua, Malik, McDonald, Timothy J., Sebastian, Shaji, Alexander, James L., Constable, Laura, Lee, James C., Murray, Charles D., Hart, Ailsa L., Irving, Peter M., Jones, Gareth-Rhys, Kok, Klaartje B., Lamb, Christopher A., Lees, Charlie W., Altmann, Daniel M., Boyton, Rosemary J., Goodhand, James R., Powell, Nick, Ahmad, Tariq
Publicado 2022

COVID-19 vaccine-induced antibody and T-cell responses in immunosuppressed patients with inflammatory bowel disease after the third vaccine dose (VIP): a multicentre, prospective,...

por Alexander, James L, Liu, Zhigang, Muñoz Sandoval, Diana, Reynolds, Catherine, Ibraheim, Hajir, Anandabaskaran, Sulak, Saifuddin, Aamir, Castro Seoane, Rocio, Anand, Nikhil, Nice, Rachel, Bewshea, Claire, D'Mello, Andrea, Constable, Laura, Jones, Gareth R, Balarajah, Sharmili, Fiorentino, Francesca, Sebastian, Shaji, Irving, Peter M, Hicks, Lucy C, Williams, Horace R T, Kent, Alexandra J, Linger, Rachel, Parkes, Miles, Kok, Klaartje, Patel, Kamal V, Teare, Julian P, Altmann, Daniel M, Goodhand, James R, Hart, Ailsa L, Lees, Charlie W, Boyton, Rosemary J, Kennedy, Nicholas A, Ahmad, Tariq, Powell, Nick
Publicado 2022

Neutralising antibody responses against SARS-CoV-2 Omicron BA.4/5 and wild-type virus in patients with inflammatory bowel disease following three doses of COVID-19 vaccine (VIP): a...

por Liu, Zhigang, Alexander, James L., Le, Kaixing, Zhou, Xin, Ibraheim, Hajir, Anandabaskaran, Sulak, Saifuddin, Aamir, Lin, Kathy Weitung, McFarlane, Leon R., Constable, Laura, Seoane, Rocio Castro, Anand, Nikhil, Bewshea, Claire, Nice, Rachel, D'Mello, Andrea, Jones, Gareth R., Balarajah, Sharmili, Fiorentino, Francesca, Sebastian, Shaji, Irving, Peter M., Hicks, Lucy C., Williams, Horace RT., Kent, Alexandra J., Linger, Rachel, Parkes, Miles, Kok, Klaartje, Patel, Kamal V., Teare, Julian P., Altmann, Daniel M., Boyton, Rosemary J., Hart, Ailsa L., Lees, Charlie W., Goodhand, James R., Kennedy, Nicholas A., Pollock, Katrina M., Ahmad, Tariq, Powell, Nick
Publicado 2023