Dual Regulatory Roles of Human AP-Endonuclease (APE1/Ref-1) in CDKN1A/p21 Expression

por Sengupta, Shiladitya, Mitra, Sankar, Bhakat, Kishor K.
Publicado 2013

Human AP-endonuclease (APE1/Ref-1) and its acetylation regulate YB-1/p300 recruitment and RNA polymerase II loading in the drug induced activation of multidrug resistance gene MDR1

por Sengupta, Shiladitya, Mantha, Anil K., Mitra, Sankar, Bhakat, Kishor K.
Publicado 2010

Subgroup-Specific Diagnostic, Prognostic, and Predictive Markers Influencing Pediatric Medulloblastoma Treatment

por Ray, Sutapa, Chaturvedi, Nagendra K., Bhakat, Kishor K., Rizzino, Angie, Mahapatra, Sidharth
Publicado 2021

APE1 and SSRP1 is overexpressed in muscle invasive bladder cancer and associated with poor survival

por Song, Heyu, Zeng, Jiping, Lele, Subodh, LaGrange, Chad A., Bhakat, Kishor K.
Publicado 2021

Regulation of the human AP-endonuclease (APE1/Ref-1) expression by the tumor suppressor p53 in response to DNA damage

por Zaky, Amira, Busso, Carlos, Izumi, Tadahide, Chattopadhyay, Ranajoy, Bassiouny, Ahmad, Mitra, Sankar, Bhakat, Kishor K.
Publicado 2008

Elevated level of acetylation of APE1 in tumor cells modulates DNA damage repair

por Sengupta, Shiladitya, Mantha, Anil K., Song, Heyu, Roychoudhury, Shrabasti, Nath, Somsubhra, Ray, Sutapa, Bhakat, Kishor K.
Publicado 2016

The human AP-endonuclease 1 (APE1) is a DNA G-quadruplex structure binding protein and regulates KRAS expression in pancreatic ductal adenocarcinoma cells

por Pramanik, Suravi, Chen, Yingling, Song, Heyu, Khutsishvili, Irine, Marky, Luis A, Ray, Sutapa, Natarajan, Amarnath, Singh, Pankaj K, Bhakat, Kishor K
Publicado 2022

Human Apurinic/Apyrimidinic Endonuclease (APE1) Is Acetylated at DNA Damage Sites in Chromatin, and Acetylation Modulates Its DNA Repair Activity

por Roychoudhury, Shrabasti, Nath, Somsubhra, Song, Heyu, Hegde, Muralidhar L., Bellot, Larry J., Mantha, Anil K., Sengupta, Shiladitya, Ray, Sutapa, Natarajan, Amarnath, Bhakat, Kishor K.
Publicado 2017

Endogenous oxidized DNA bases and APE1 regulate the formation of G-quadruplex structures in the genome

por Roychoudhury, Shrabasti, Pramanik, Suravi, Harris, Hannah L., Tarpley, Mason, Sarkar, Aniruddha, Spagnol, Gaelle, Sorgen, Paul L., Chowdhury, Dipanjan, Band, Vimla, Klinkebiel, David, Bhakat, Kishor K.
Publicado 2020

Nucleolar accumulation of APE1 depends on charged lysine residues that undergo acetylation upon genotoxic stress and modulate its BER activity in cells

por Lirussi, Lisa, Antoniali, Giulia, Vascotto, Carlo, D'Ambrosio, Chiara, Poletto, Mattia, Romanello, Milena, Marasco, Daniela, Leone, Marilisa, Quadrifoglio, Franco, Bhakat, Kishor K., Scaloni, Andrea, Tell, Gianluca
Publicado 2012

Regulation of limited N-terminal proteolysis of APE1 in tumor via acetylation and its role in cell proliferation

por Bhakat, Kishor K., Sengupta, Shiladitya, Adeniyi, Victor F., Roychoudhury, Shrabasti, Nath, Somsubhra, Bellot, Larry J., Feng, Dan, Mantha, Anil K., Sinha, Mala, Qiu, Suimin, Luxon, Bruce A.
Publicado 2016

Pan-Cancer Analysis Reveals the Diverse Landscape of Novel Sense and Antisense Fusion Transcripts

por Vellichirammal, Neetha Nanoth, Albahrani, Abrar, Banwait, Jasjit K., Mishra, Nitish K., Li, You, Roychoudhury, Shrabasti, Kling, Mathew J., Mirza, Sameer, Bhakat, Kishor K., Band, Vimla, Joshi, Shantaram S., Guda, Chittibabu
Publicado 2020

STAT3 Inhibition Attenuates MYC Expression by Modulating Co-Activator Recruitment and Suppresses Medulloblastoma Tumor Growth by Augmenting Cisplatin Efficacy In Vivo

por Rohrer, Kyle A., Song, Heyu, Akbar, Anum, Chen, Yingling, Pramanik, Suravi, Wilder, Phillip J., McIntyre, Erin M., Chaturvedi, Nagendra K., Bhakat, Kishor K., Rizzino, Angie, Coulter, Don W., Ray, Sutapa
Publicado 2023