Synthesis and Biological Evaluation of Coumarin Triazoles as Dual Inhibitors of Cholinesterases and β-Secretase

por Sharma, Ankita, Bharate, Sandip B.
Publicado 2023

Discovery of Pongol, the Furanoflavonoid, as an Inhibitor of CDK7/Cyclin H/MAT1 and Its Preliminary Structure–Activity Relationship

por Bhurta, Deendyal, Bharate, Sandip B.
Publicado 2022

Biotransformation, Using Recombinant CYP450-Expressing Baker’s Yeast Cells, Identifies a Novel CYP2D6.10(A122V) Variant Which Is a Superior Metabolizer of Codeine to Morphine Than...

por Williams, Ibidapo S., Gatchie, Linda, Bharate, Sandip B., Chaudhuri, Bhabatosh
Publicado 2018

Selection of a Water-Soluble Salt Form of a Preclinical Candidate, IIIM-290: Multiwell-Plate Salt Screening and Characterization

por Kumar, Vikas, Bharate, Sandip B., Vishwakarma, Ram A., Bharate, Sonali S.
Publicado 2018

Malononitrile-activated synthesis and anti-cholinesterase activity of styrylquinoxalin-2(1H)-ones

por Mahajan, Sheena, Slathia, Nancy, Nuthakki, Vijay K., Bharate, Sandip B., Kapoor, Kamal K.
Publicado 2020

Antitumour potential of BPT: a dual inhibitor of cdk4 and tubulin polymerization

por Mahale, S, Bharate, S B, Manda, S, Joshi, P, Jenkins, P R, Vishwakarma, R A, Chaudhuri, B
Publicado 2015

Khellinoflavanone, a Semisynthetic Derivative of Khellin, Overcomes Benzo[a]pyrene Toxicity in Human Normal and Cancer Cells That Express CYP1A1

por Sharma, Rajni, Williams, Ibidapo S., Gatchie, Linda, Sonawane, Vinay R., Chaudhuri, Bhabatosh, Bharate, Sandip B.
Publicado 2018

Nonantioxidant Tetramethoxystilbene Abrogates α-Synuclein-Induced Yeast Cell Death but Not That Triggered by the Bax or βA4 Peptide

por Derf, Asma, Mudududdla, Ramesh, Akintade, Damilare, Williams, Ibidapo S., Abdullaha, Mohd, Chaudhuri, Bhabatosh, Bharate, Sandip B.
Publicado 2018

Discovery of Helminthosporin, an Anthraquinone Isolated from Rumex abyssinicus Jacq as a Dual Cholinesterase Inhibitor

por Augustin, Ntemafack, Nuthakki, Vijay K., Abdullaha, Mohd., Hassan, Qazi Parvaiz, Gandhi, Sumit G., Bharate, Sandip B.
Publicado 2020

Boeravinone B, A Novel Dual Inhibitor of NorA Bacterial Efflux Pump of Staphylococcus aureus and Human P-Glycoprotein, Reduces the Biofilm Formation and Intracellular Invasion of B...

por Singh, Samsher, Kalia, Nitin P., Joshi, Prashant, Kumar, Ajay, Sharma, Parduman R., Kumar, Ashok, Bharate, Sandip B., Khan, Inshad A.
Publicado 2017

Preclinical Development of Crocus sativus-Based Botanical Lead IIIM-141 for Alzheimer’s Disease: Chemical Standardization, Efficacy, Formulation Development, Pharmacokinetics, and...

por Bharate, Sonali S., Kumar, Vikas, Singh, Gurdarshan, Singh, Amarinder, Gupta, Mehak, Singh, Deepika, Kumar, Ajay, Vishwakarma, Ram A., Bharate, Sandip B.
Publicado 2018

Methoxy-naphthyl-Linked N-Benzyl Pyridinium Styryls as Dual Cholinesterase Inhibitors: Design, Synthesis, Biological Evaluation, and Structure–Activity Relationship

por Abdullaha, Mohd, Banoo, Razia, Nuthakki, Vijay K., Sharma, Mohit, Kaur, Sukhleen, Thakur, Shikha, Kumar, Ajay, Jadhav, Hemant R., Bharate, Sandip B.
Publicado 2023

IIIM-941, a Stilbene Derivative Inhibits NLRP3 Inflammasome Activation by Inducing Autophagy

por Ali, Mehboob, Gupta, Mehak, Wani, Abubakar, Sharma, Ankita, Abdullaha, Mohd, Kour, Dilpreet, Choudhary, Sushil, Bharate, Sandip B., Singh, Gurdarshan, Kumar, Ajay
Publicado 2021

Rational Design, Synthesis and Biological Evaluation of Pyrimidine-4,6-diamine derivatives as Type-II inhibitors of FLT3 Selective Against c-KIT

por Bharate, Jaideep B., McConnell, Nicholas, Naresh, Gunaganti, Zhang, Lingtian, Lakkaniga, Naga Rajiv, Ding, Lucky, Shah, Neil P., Frett, Brendan, Li, Hong-yu
Publicado 2018

A novel quinazolinone derivative induces cytochrome c interdependent apoptosis and autophagy in human leukemia MOLT-4 cells

por Kumar, Suresh, Guru, Santosh Kumar, Pathania, Anup Singh, Mupparapu, Nagaraju, Kumar, Ajay, Malik, Fayaz, Bharate, Sandip B., Naveed Ahmed, Qazi, Vishwakarma, Ram A., Bhushan, Shashi
Publicado 2014

Tandem Ring Opening/Intramolecular [2 + 2] Cycloaddition Reaction for the Synthesis of Cyclobutane Fused Thiazolino-2-Pyridones

por Tyagi, Mohit, Adolfsson, Dan E., Singh, Pardeep, Ådén, Jörgen, Jayaweera, Sanduni Wasana, Gharibyan, Anna, Bharate, Jaideep B., Kiss, Anita, Sarkar, Souvik, Olofsson, Anders, Almqvist, Fredrik
Publicado 2021

Correction: Chrysomycins A–C, antileukemic naphthocoumarins from Streptomyces sporoverrucosus

por Jain, Shreyans K., Pathania, Anup S., Parshad, Rajinder, Raina, Chandji, Ali, Asif, Gupta, Ajai P., Kushwaha, Manoj, Aravinda, Subrayashastry, Bhushan, Shashi, Bharate, Sandip B., Vishwakarma, Ram A.
Publicado 2022

Quantitative Determination and Characterization of a Kashmir Saffron (Crocus sativus L.)-Based Botanical Supplement Using Single-Laboratory Validation Study by HPLC-PDA with LC–MS/...

por Girme, Aboli, Saste, Ganesh, Pawar, Sandeep, Ghule, Chetana, Mirgal, Amit, Patel, Saurabh, Tiwari, Anshuly, Ghoshal, Sautik, Bharate, Sandip B., Bharate, Sonali S., Reddy, D. Srinivasa, Vishwakarma, Ram A., Hingorani, Lal
Publicado 2021

Cell-intrinsic Aryl Hydrocarbon Receptor signalling is required for the resolution of injury-induced colonic stem cells

por Shah, Kathleen, Maradana, Muralidhara Rao, Joaquina Delàs, M., Metidji, Amina, Graelmann, Frederike, Llorian, Miriam, Chakravarty, Probir, Li, Ying, Tolaini, Mauro, Shapiro, Michael, Kelly, Gavin, Cheshire, Chris, Bhurta, Deendyal, Bharate, Sandip B., Stockinger, Brigitta
Publicado 2022

Strategies to target SARS-CoV-2 entry and infection using dual mechanisms of inhibition by acidification inhibitors

por Prabhakara, Chaitra, Godbole, Rashmi, Sil, Parijat, Jahnavi, Sowmya, Gulzar, Shah-e-Jahan, van Zanten, Thomas S., Sheth, Dhruv, Subhash, Neeraja, Chandra, Anchal, Shivaraj, Akshatha, Panikulam, Patricia, U, Ibrahim, Nuthakki, Vijay Kumar, Puthiyapurayil, Theja Parassini, Ahmed, Riyaz, Najar, Ashaq Hussain, Lingamallu, Sai Manoz, Das, Snigdhadev, Mahajan, Bhagyashri, Vemula, Praveen, Bharate, Sandip B., Singh, Parvinder Pal, Vishwakarma, Ram, Guha, Arjun, Sundaramurthy, Varadharajan, Mayor, Satyajit
Publicado 2021