Enhancing antisense efficacy with multimers and multi-targeting oligonucleotides (MTOs) using cleavable linkers

por Subramanian, Romesh R., Wysk, Mark A., Ogilvie, Kathleen M., Bhat, Abhijit, Kuang, Bing, Rockel, Thomas D., Weber, Markus, Uhlmann, Eugen, Krieg, Arthur M.
Publicado 2015

Aldehyde Tag Coupled with HIPS Chemistry Enables the Production of ADCs Conjugated Site-Specifically to Different Antibody Regions with Distinct in Vivo Efficacy and PK Outcomes

por Drake, Penelope M., Albers, Aaron E., Baker, Jeanne, Banas, Stefanie, Barfield, Robyn M., Bhat, Abhijit S., de Hart, Gregory W., Garofalo, Albert W., Holder, Patrick, Jones, Lesley C., Kudirka, Romas, McFarland, Jesse, Zmolek, Wes, Rabuka, David
Publicado 2014

Inhibiting complex IL-17A and IL-17RA interactions with a linear peptide

por Liu, Shenping, Desharnais, Joel, Sahasrabudhe, Parag V., Jin, Ping, Li, Wei, Oates, Bryan D., Shanker, Suman, Banker, Mary Ellen, Chrunyk, Boris A., Song, Xi, Feng, Xidong, Griffor, Matt, Jimenez, Judith, Chen, Gang, Tumelty, David, Bhat, Abhijit, Bradshaw, Curt W., Woodnutt, Gary, Lappe, Rodney W., Thorarensen, Atli, Qiu, Xiayang, Withka, Jane M., Wood, Lauren D.
Publicado 2016