Re-programming tumour cell metabolism to treat cancer: no lone target for lonidamine

por Bhutia, Yangzom D., Babu, Ellappan, Ganapathy, Vadivel
Publicado 2016

Cell-Surface and Nuclear Receptors in the Colon as Targets for Bacterial Metabolites and Its Relevance to Colon Health

por Sivaprakasam, Sathish, Bhutia, Yangzom D., Ramachandran, Sabarish, Ganapathy, Vadivel
Publicado 2017

SLC6A14 and SLC38A5 Drive the Glutaminolysis and Serine–Glycine–One-Carbon Pathways in Cancer

por Sniegowski, Tyler, Korac, Ksenija, Bhutia, Yangzom D., Ganapathy, Vadivel
Publicado 2021

Consequences of NaCT/SLC13A5/mINDY deficiency: good versus evil, separated only by the blood–brain barrier

por Kopel, Jonathan J., Bhutia, Yangzom D., Sivaprakasam, Sathish, Ganapathy, Vadivel
Publicado 2021

Pharmacologic inducers of the uric acid exporter ABCG2 as potential drugs for treatment of gouty arthritis

por Ristic, Bojana, Sikder, Mohd Omar Faruk, Bhutia, Yangzom D., Ganapathy, Vadivel
Publicado 2020

Unconventional Functions of Amino Acid Transporters: Role in Macropinocytosis (SLC38A5/SLC38A3) and Diet-Induced Obesity/Metabolic Syndrome (SLC6A19/SLC6A14/SLC6A6)

por Bhutia, Yangzom D., Mathew, Marilyn, Sivaprakasam, Sathish, Ramachandran, Sabarish, Ganapathy, Vadivel
Publicado 2022

Polycystic ovary syndrome and iron overload: biochemical link and underlying mechanisms with potential novel therapeutic avenues

por Mathew, Marilyn, Sivaprakasam, Sathish, Phy, Jennifer L., Bhutia, Yangzom D., Ganapathy, Vadivel
Publicado 2023

Transporter-Guided Delivery of Nanoparticles to Improve Drug Permeation across Cellular Barriers and Drug Exposure to Selective Cell Types

por Kou, Longfa, Bhutia, Yangzom D., Yao, Qing, He, Zhonggui, Sun, Jin, Ganapathy, Vadivel
Publicado 2018

Plasma Membrane Na(+)-Coupled Citrate Transporter (SLC13A5) and Neonatal Epileptic Encephalopathy

por Bhutia, Yangzom D., Kopel, Jonathan J., Lawrence, John J., Neugebauer, Volker, Ganapathy, Vadivel
Publicado 2017

PEPT1 is essential for the growth of pancreatic cancer cells: a viable drug target

por Schniers, Bradley K., Rajasekaran, Devaraja, Korac, Ksenija, Sniegowski, Tyler, Ganapathy, Vadivel, Bhutia, Yangzom D.
Publicado 2021

RETRACTED ARTICLE: Identification of a novel Na(+)-coupled Fe(3+)-citrate transport system, distinct from mammalian INDY, for uptake of citrate in mammalian cells

por Ogura, Jiro, Babu, Ellappan, Miyauchi, Seiji, Ramachandran, Sabarish, Nemeth, Elizebeta, Bhutia, Yangzom D., Ganapathy, Vadivel
Publicado 2018

Retraction Note: Identification of a novel Na(+)-coupled Fe(3+)-citrate transport system, distinct from mammalian INDY, for uptake of citrate in mammalian cells

por Ogura, Jiro, Babu, Ellappan, Miyauchi, Seiji, Ramachandran, Sabarish, Nemeth, Elizebeta, Bhutia, Yangzom D., Ganapathy, Vadivel
Publicado 2018

Transporter-Targeted Nano-Sized Vehicles for Enhanced and Site-Specific Drug Delivery

por Kou, Longfa, Yao, Qing, Zhang, Hailin, Chu, Maoping, Bhutia, Yangzom D., Chen, Ruijie, Ganapathy, Vadivel
Publicado 2020

Binding of Citrate-Fe(3+) to Plastic Culture Dishes, an Artefact Useful as a Simple Technique to Screen for New Iron Chelators

por Ogura, Jiro, Sato, Toshihiro, Higuchi, Kei, Sivaprakasam, Sathish, Kopel, Jonathan, Bhutia, Yangzom D., Ganapathy, Vadivel
Publicado 2022

Carbidopa, an activator of aryl hydrocarbon receptor, suppresses IDO1 expression in pancreatic cancer and decreases tumor growth

por Korac, Ksenija, Rajasekaran, Devaraja, Sniegowski, Tyler, Schniers, Bradley K., Ibrahim, Andrew F., Bhutia, Yangzom D.
Publicado 2022

SLC6A14, a Na(+)/Cl(−)-coupled amino acid transporter, functions as a tumor promoter in colon and is a target for Wnt signaling

por Sikder, Mohd O. F., Sivaprakasam, Sathish, Brown, Timothy P., Thangaraju, Muthusamy, Bhutia, Yangzom D., Ganapathy, Vadivel
Publicado 2020

α-Methyl-l-tryptophan as a weight-loss agent in multiple models of obesity in mice

por Sivaprakasam, Sathish, Ramachandran, Sabarish, Sikder, Mohd Omar Faruk, Bhutia, Yangzom D., Wachtel, Mitchell W., Ganapathy, Vadivel
Publicado 2021

Sigma Receptors: Novel Regulators of Iron/Heme Homeostasis and Ferroptosis

por Nguyen, Nhi T., Jaramillo-Martinez, Valeria, Mathew, Marilyn, Suresh, Varshini V., Sivaprakasam, Sathish, Bhutia, Yangzom D., Ganapathy, Vadivel
Publicado 2023

A Proton-Coupled Transport System for β-Hydroxy-β-Methylbutyrate (HMB) in Blood–Brain Barrier Endothelial Cell Line hCMEC/D3

por Higuchi, Kei, Sivaprakasam, Sathish, Sennoune, Souad R., Ogura, Jiro, Bhutia, Yangzom D., Rueda, Ricardo, Pereira, Suzette L., Ganapathy, Vadivel
Publicado 2021

Deletion of Slc6a14 reduces cancer growth and metastatic spread and improves survival in KPC mouse model of spontaneous pancreatic cancer

por Schniers, Bradley K., Wachtel, Mitchell S., Sharma, Meenu, Korac, Ksenija, Rajasekaran, Devaraja, Yang, Shengping, Sniegowski, Tyler, Ganapathy, Vadivel, Bhutia, Yangzom D.
Publicado 2022