Continued cytoadherence of Plasmodium falciparum infected red blood cells after antimalarial treatment

por Hughes, Katie R., Biagini, Giancarlo A., Craig, Alister G.
Publicado 2010

A yeast expression system for functional and pharmacological studies of the malaria parasite Ca(2+)/H(+) antiporter

por Salcedo-Sora, J Enrique, Ward, Steve A, Biagini, Giancarlo A
Publicado 2012

OptiMal-PK: an internet-based, user-friendly interface for the mathematical-based design of optimized anti-malarial treatment regimens

por Aljayyoussi, Ghaith, Kay, Katherine, Ward, Stephen A., Biagini, Giancarlo A.
Publicado 2016

Intracellular PD Modelling (PD(i)) for the Prediction of Clinical Activity of Increased Rifampicin Dosing

por Aljayyoussi, Ghaith, Donnellan, Samantha, Ward, Stephen A., Biagini, Giancarlo A.
Publicado 2019

The proliferating cell hypothesis: a metabolic framework for Plasmodium growth and development()

por Salcedo-Sora, J. Enrique, Caamano-Gutierrez, Eva, Ward, Stephen A., Biagini, Giancarlo A.
Publicado 2014

Loss of pH Control in Plasmodium falciparum Parasites Subjected to Oxidative Stress

por van Schalkwyk, Donelly A., Saliba, Kevin J., Biagini, Giancarlo A., Bray, Patrick G., Kirk, Kiaran
Publicado 2013

Rapid kill of malaria parasites by artemisinin and semi-synthetic endoperoxides involves ROS-dependent depolarization of the membrane potential

por Antoine, Thomas, Fisher, Nicholas, Amewu, Richard, O'Neill, Paul M., Ward, Stephen A., Biagini, Giancarlo A.
Publicado 2014

Pharmacokinetic-Pharmacodynamic modelling of intracellular Mycobacterium tuberculosis growth and kill rates is predictive of clinical treatment duration

por Aljayyoussi, Ghaith, Jenkins, Victoria A., Sharma, Raman, Ardrey, Alison, Donnellan, Samantha, Ward, Stephen A., Biagini, Giancarlo A.
Publicado 2017

Intracellular Pharmacodynamic Modeling Is Predictive of the Clinical Activity of Fluoroquinolones against Tuberculosis

por Donnellan, Samantha, Aljayyoussi, Ghaith, Moyo, Emmanuel, Ardrey, Alison, Martinez-Rodriguez, Carmen, Ward, Stephen A., Biagini, Giancarlo A.
Publicado 2019

Glycerol: An unexpected major metabolite of energy metabolism by the human malaria parasite

por Lian, Lu-Yun, Al-Helal, Mohammed, Roslaini, Abd Majid, Fisher, Nicholas, Bray, Patrick G, Ward, Stephen A, Biagini, Giancarlo A
Publicado 2009

A Click Chemistry‐Based Proteomic Approach Reveals that 1,2,4‐Trioxolane and Artemisinin Antimalarials Share a Common Protein Alkylation Profile

por Ismail, Hanafy M., Barton, Victoria E., Panchana, Matthew, Charoensutthivarakul, Sitthivut, Biagini, Giancarlo A., Ward, Stephen A., O'Neill, Paul M.
Publicado 2016

A Click Chemistry‐Based Proteomic Approach Reveals that 1,2,4‐Trioxolane and Artemisinin Antimalarials Share a Common Protein Alkylation Profile

por Ismail, Hanafy M., Barton, Victoria E., Panchana, Matthew, Charoensutthivarakul, Sitthivut, Biagini, Giancarlo A., Ward, Stephen A., O'Neill, Paul M.
Publicado 2016

Antimalarial pharmacology and therapeutics of atovaquone

por Nixon, Gemma L., Moss, Darren M., Shone, Alison E., Lalloo, David G., Fisher, Nicholas, O'Neill, Paul M., Ward, Stephen A., Biagini, Giancarlo A.
Publicado 2013

A Quantitative Method for the Study of HIV-1 and Mycobacterium tuberculosis Coinfection

por Donnellan, Samantha, Pennington, Shaun H, Ruggiero, Alessandra, Martinez-Rodriguez, Carmen, Pouget, Marion, Thomas, Jordan, Ward, Steve A, Pollakis, Georgios, Biagini, Giancarlo A, Paxton, William A
Publicado 2022

Quantitation of tizoxanide in multiple matrices to support cell culture, animal and human research.

por Neary, Megan, Arshad, Usman, Tatham, Lee, Pertinez, Henry, Box, Helen, Rajoli, Rajith KR, Valentijn, Anthony, Sharp, Joanne, Rannard, Steve P, Biagini, Giancarlo A, Curley, Paul, Owen, Andrew
Publicado 2021

The Molecular Basis of Folate Salvage in Plasmodium falciparum: CHARACTERIZATION OF TWO FOLATE TRANSPORTERS

por Salcedo-Sora, J. Enrique, Ochong, Edwin, Beveridge, Susan, Johnson, David, Nzila, Alexis, Biagini, Giancarlo A., Stocks, Paul A., O'Neill, Paul M., Krishna, Sanjeev, Bray, Patrick G., Ward, Stephen A.
Publicado 2011

Cytochrome b Mutation Y268S Conferring Atovaquone Resistance Phenotype in Malaria Parasite Results in Reduced Parasite bc(1) Catalytic Turnover and Protein Expression

por Fisher, Nicholas, Abd Majid, Roslaini, Antoine, Thomas, Al-Helal, Mohammed, Warman, Ashley J., Johnson, David J., Lawrenson, Alexandre S., Ranson, Hilary, O'Neill, Paul M., Ward, Stephen A., Biagini, Giancarlo A.
Publicado 2012

Treatment responses to Azithromycin and Ciprofloxacin in uncomplicated Salmonella Typhi infection: A comparison of Clinical and Microbiological Data from a Controlled Human Infecti...

por Jin, Celina, Gibani, Malick M., Pennington, Shaun H., Liu, Xinxue, Ardrey, Alison, Aljayyoussi, Ghaith, Moore, Maria, Angus, Brian, Parry, Christopher M., Biagini, Giancarlo A., Feasey, Nicholas A., Pollard, Andrew J.
Publicado 2019

Sars-Cov-2 Infects an Upper Airway Model Derived from Induced Pluripotent Stem Cells

por Djidrovski, Ivo, Georgiou, Maria, Hughes, Grant L., Patterson, Edward I., Casas-Sanchez, Aitor, Pennington, Shaun H., Biagini, Giancarlo A., Moya-Molina, Marina, Bor, Jelle, Smit, Martine J., Chung, Git, Lako, Majlinda, Armstrong, Lyle
Publicado 2021

Targeting the Ubiquinol-Reduction (Q(i)) Site of the Mitochondrial Cytochrome bc(1) Complex for the Development of Next Generation Quinolone Antimalarials

por Amporndanai, Kangsa, Pinthong, Nattapon, O’Neill, Paul M., Hong, W. David, Amewu, Richard K., Pidathala, Chandrakala, Berry, Neil G., Leung, Suet C., Ward, Stephen A., Biagini, Giancarlo A., Hasnain, S. Samar, Antonyuk, Svetlana V.
Publicado 2022