Role of ATM in the telomere response to the G-quadruplex ligand 360A

por Pennarun, Gaëlle, Granotier, Christine, Hoffschir, Françoise, Mandine, Eliane, Biard, Denis, Gauthier, Laurent R., Boussin, François D.
Publicado 2008

PARP inhibition versus PARP-1 silencing: different outcomes in terms of single-strand break repair and radiation susceptibility

por Godon, Camille, Cordelières, Fabrice P., Biard, Denis, Giocanti, Nicole, Mégnin-Chanet, Frédérique, Hall, Janet, Favaudon, Vincent
Publicado 2008

Role of the ubiquitin-binding domain of Polη in Rad18-independent translesion DNA synthesis in human cell extracts

por Schmutz, Valérie, Janel-Bintz, Régine, Wagner, Jérôme, Biard, Denis, Shiomi, Naoko, Fuchs, Robert P., Cordonnier, Agnès M.
Publicado 2010

Partial complementation of a DNA ligase I deficiency by DNA ligase III and its impact on cell survival and telomere stability in mammalian cells

por Le Chalony, Catherine, Hoffschir, Françoise, Gauthier, Laurent R., Gross, Julia, Biard, Denis S., Boussin, François D., Pennaneach, Vincent
Publicado 2012

ATR contributes to telomere maintenance in human cells

por Pennarun, Gaëlle, Hoffschir, Françoise, Revaud, Deborah, Granotier, Christine, Gauthier, Laurent R., Mailliet, Patrick, Biard, Denis S., Boussin, François D.
Publicado 2010

Translesion synthesis mechanisms depend on the nature of DNA damage in UV-irradiated human cells

por Quinet, Annabel, Martins, Davi Jardim, Vessoni, Alexandre Teixeira, Biard, Denis, Sarasin, Alain, Stary, Anne, Menck, Carlos Frederico Martins
Publicado 2016

Breast cancer stem cell-like cells generated during TGFβ-induced EMT are radioresistant

por Konge, Julie, Leteurtre, François, Goislard, Maud, Biard, Denis, Morel-Altmeyer, Sandrine, Vaurijoux, Aurélie, Gruel, Gaetan, Chevillard, Sylvie, Lebeau, Jérôme
Publicado 2018

Long Term Gene Expression in Human Induced Pluripotent Stem Cells and Cerebral Organoids to Model a Neurodegenerative Disease

por Nassor, Ferid, Jarray, Rafika, Biard, Denis S. F., Maïza, Auriane, Papy-Garcia, Dulce, Pavoni, Serena, Deslys, Jean-Philippe, Yates, Frank
Publicado 2020

Rad51 and DNA-PKcs are involved in the generation of specific telomere aberrations induced by the quadruplex ligand 360A that impair mitotic cell progression and lead to cell death

por Gauthier, Laurent R., Granotier, Christine, Hoffschir, Françoise, Etienne, Olivier, Ayouaz, Ali, Desmaze, Chantal, Mailliet, Patrick, Biard, Denis S., Boussin, François D.
Publicado 2011

ALT cancer cells are specifically sensitive to lysine acetyl transferase inhibition

por Bakhos-Douaihy, Dalal, Desmaze, Chantal, Jeitany, Maya, Gauthier, Laurent R., Biard, Denis, Junier, Marie-Pierre, Chneiweiss, Hervé, Boussin, François D.
Publicado 2019

Pyrimidine Pool Disequilibrium Induced by a Cytidine Deaminase Deficiency Inhibits PARP-1 Activity, Leading to the Under Replication of DNA

por Gemble, Simon, Ahuja, Akshay, Buhagiar-Labarchède, Géraldine, Onclercq-Delic, Rosine, Dairou, Julien, Biard, Denis S. F., Lambert, Sarah, Lopes, Massimo, Amor-Guéret, Mounira
Publicado 2015

Loss of CD24 promotes radiation- and chemo-resistance by inducing stemness properties associated with a hybrid E/M state in breast cancer cells

por Bontemps, Isaline, Lallemand, Celine, Biard, Denis, Dechamps, Nathalie, Kortulewski, Thierry, Bourneuf, Emmanuelle, Siberchicot, Capucine, Boussin, François, Chevillard, Sylvie, Campalans, Anna, Lebeau, Jerome
Publicado 2022

The impact of cyclin-dependent kinase 5 depletion on poly(ADP-ribose) polymerase activity and responses to radiation

por Bolin, Celeste, Boudra, Mohammed-Tayyib, Fernet, Marie, Vaslin, Laurence, Pennaneach, Vincent, Zaremba, Tomasz, Biard, Denis, Cordelières, Fabrice P., Favaudon, Vincent, Mégnin-Chanet, Frédérique, Hall, Janet
Publicado 2011

Characterization of DNA ADP-ribosyltransferase activities of PARP2 and PARP3: new insights into DNA ADP-ribosylation

por Zarkovic, Gabriella, Belousova, Ekaterina A, Talhaoui, Ibtissam, Saint-Pierre, Christine, Kutuzov, Mikhail M, Matkarimov, Bakhyt T, Biard, Denis, Gasparutto, Didier, Lavrik, Olga I, Ishchenko, Alexander A
Publicado 2018

Novel Anti-Metastatic Action of Cidofovir Mediated by Inhibition of E6/E7, CXCR4 and Rho/ROCK Signaling in HPV(+) Tumor Cells

por Amine, Abdessamad, Rivera, Sofia, Opolon, Paule, Dekkal, Mehdi, Biard, Denis S. F., Bouamar, Hakim, Louache, Fawzia, McKay, Michael J., Bourhis, Jean, Deutsch, Eric, Vozenin-Brotons, Marie-Catherine
Publicado 2009

A new phosphorylated form of Ku70 identified in resistant leukemic cells confers fast but unfaithful dna repair in cancer cell lines

por Bouley, Julien, Saad, Lina, Grall, Romain, Schellenbauer, Amelie, Biard, Denis, Paget, Vincent, Morel-Altmeyer, Sandrine, Guipaud, Olivier, Chambon, Christophe, Salles, Bernard, Maloum, Karim, Merle-Béral, Hélène, Chevillard, Sylvie, Delic, Jozo
Publicado 2015

PARP1–TDP1 coupling for the repair of topoisomerase I–induced DNA damage

por Das, Benu Brata, Huang, Shar-yin N., Murai, Junko, Rehman, Ishita, Amé, Jean-Christophe, Sengupta, Souvik, Das, Subhendu K., Majumdar, Papiya, Zhang, Hongliang, Biard, Denis, Majumder, Hemanta K., Schreiber, Valérie, Pommier, Yves
Publicado 2014

Reactive oxygen species levels control NF-κB activation by low dose deferasirox in erythroid progenitors of low risk myelodysplastic syndromes

por Meunier, Mathieu, Ancelet, Sarah, Lefebvre, Christine, Arnaud, Josiane, Garrel, Catherine, Pezet, Mylène, Wang, Yan, Faure, Patrice, Szymanski, Gautier, Duployez, Nicolas, Preudhomme, Claude, Biard, Denis, Polack, Benoit, Cahn, Jean-Yves, Moulis, Jean Marc, Park, Sophie
Publicado 2017

Targeting nonsense-mediated mRNA decay in colorectal cancers with microsatellite instability

por Bokhari, A’dem, Jonchere, Vincent, Lagrange, Anaïs, Bertrand, Romane, Svrcek, Magali, Marisa, Laetitia, Buhard, Olivier, Greene, Malorie, Demidova, Anastasia, Jia, Jieshuang, Adriaenssens, Eric, Chassat, Thierry, Biard, Denis S., Flejou, Jean-François, Lejeune, Fabrice, Duval, Alex, Collura, Ada
Publicado 2018

Phospho-Ku70 induced by DNA damage interacts with RNA Pol II and promotes the formation of phospho-53BP1 foci to ensure optimal cNHEJ

por Schellenbauer, Amelie, Guilly, Marie-Noelle, Grall, Romain, Le Bars, Romain, Paget, Vincent, Kortulewski, Thierry, Sutcu, Haser, Mathé, Cécile, Hullo, Marie, Biard, Denis, Leteurtre, François, Barroca, Vilma, Corre, Youenn, Irbah, Lamya, Rass, Emilie, Theze, Benoit, Bertrand, Pascale, Demmers, Jeroen A A, Guirouilh-Barbat, Josée, Lopez, Bernard S, Chevillard, Sylvie, Delic, Jozo
Publicado 2021