Dual miRNases for Triple Incision of miRNA Target: Design Concept and Catalytic Performance

por Patutina, Olga, Chiglintseva, Daria, Bichenkova, Elena, Gaponova, Svetlana, Mironova, Nadezhda, Vlassov, Valentin, Zenkova, Marina
Publicado 2020

Site-Selective Artificial Ribonucleases: Renaissance of Oligonucleotide Conjugates for Irreversible Cleavage of RNA Sequences

por Staroseletz, Yaroslav, Gaponova, Svetlana, Patutina, Olga, Bichenkova, Elena, Amirloo, Bahareh, Heyman, Thomas, Chiglintseva, Daria, Zenkova, Marina
Publicado 2021

Bulge-Forming miRNases Cleave Oncogenic miRNAs at the Central Loop Region in a Sequence-Specific Manner

por Patutina, Olga, Chiglintseva, Daria, Amirloo, Bahareh, Clarke, David, Gaponova, Svetlana, Vlassov, Valentin, Bichenkova, Elena, Zenkova, Marina
Publicado 2022

“Bind, cleave and leave”: multiple turnover catalysis of RNA cleavage by bulge–loop inducing supramolecular conjugates

por Amirloo, Bahareh, Staroseletz, Yaroslav, Yousaf, Sameen, Clarke, David J, Brown, Tom, Aojula, Harmesh, Zenkova, Marina A, Bichenkova, Elena V
Publicado 2021

Sequence-Specific Detection of Unlabeled Nucleic Acid Biomarkers Using a “One-Pot” 3D Molecular Sensor

por Yousaf, Sameen, King, Patrick J. S., Miller, Aline F., Saiani, Alberto, Clarke, David J., Trivoluzzi, Linda T., Aojula, Harmesh S., Bichenkova, Elena V.
Publicado 2019

Site-Selective Artificial Ribonucleases: Oligonucleotide Conjugates Containing Multiple Imidazole Residues in the Catalytic Domain

por Beloglazova, Natalia G., Fabani, Martin M., Polushin, Nikolai N., Sil'nikov, Vladimir V., Vlassov, Valentin V., Bichenkova, Elena V., Zenkova, Marina A.
Publicado 2011

Strict conformational demands of RNA cleavage in bulge-loops created by peptidyl-oligonucleotide conjugates

por Staroseletz, Yaroslav, Amirloo, Bahareh, Williams, Aled, Lomzov, Alexander, Burusco, Kepa K, Clarke, David J, Brown, Tom, Zenkova, Marina A, Bichenkova, Elena V
Publicado 2020

Catalytic Knockdown of miR-21 by Artificial Ribonuclease: Biological Performance in Tumor Model

por Patutina, Olga A., Miroshnichenko, Svetlana K., Mironova, Nadezhda L., Sen’kova, Aleksandra V., Bichenkova, Elena V., Clarke, David J., Vlassov, Valentin V., Zenkova, Marina A.
Publicado 2019