TFIIB Is Only ∼9 Å Away from the 5'-End of a Trimeric RNA Primer in a Functional RNA Polymerase II Preinitiation Complex

por Bick, Matthew J., Malik, Sohail, Mustaev, Arkady, Darst, Seth A.
Publicado 2015

Modular repeat protein sculpting using rigid helical junctions

por Brunette, TJ, Bick, Matthew J., Hansen, Jesse M., Chow, Cameron M., Kollman, Justin M., Baker, David
Publicado 2020

Retroviral restriction factors: new mechanisms of innate immunity

por Wolf, Daniel, Gao, Guangxia, Guo, Xuemin, Bick, Matthew J, Carroll, John-William N, MacDonald, Margaret R, Goff, Stephen P
Publicado 2009

An enumerative algorithm for de novo design of proteins with diverse pocket structures

por Basanta, Benjamin, Bick, Matthew J., Bera, Asim K., Norn, Christoffer, Chow, Cameron M., Carter, Lauren P., Goreshnik, Inna, Dimaio, Frank, Baker, David
Publicado 2020

Tight and specific lanthanide binding in a de novo TIM barrel with a large internal cavity designed by symmetric domain fusion

por Caldwell, Shane J., Haydon, Ian C., Piperidou, Nikoletta, Huang, Po-Ssu, Bick, Matthew J., Sjöström, H. Sebastian, Hilvert, Donald, Baker, David, Zeymer, Cathleen
Publicado 2020

Computational design of environmental sensors for the potent opioid fentanyl

por Bick, Matthew J, Greisen, Per J, Morey, Kevin J, Antunes, Mauricio S, La, David, Sankaran, Banumathi, Reymond, Luc, Johnsson, Kai, Medford, June I, Baker, David
Publicado 2017

Computational design of closely related proteins that adopt two well-defined but structurally divergent folds

por Wei, Kathy Y., Moschidi, Danai, Bick, Matthew J., Nerli, Santrupti, McShan, Andrew C., Carter, Lauren P., Huang, Po-Ssu, Fletcher, Daniel A., Sgourakis, Nikolaos G., Boyken, Scott E., Baker, David
Publicado 2020

Computational design of a synthetic PD-1 agonist

por Bryan, Cassie M., Rocklin, Gabriel J., Bick, Matthew J., Ford, Alex, Majri-Morrison, Sonia, Kroll, Ashley V., Miller, Chad J., Carter, Lauren, Goreshnik, Inna, Kang, Alex, DiMaio, Frank, Tarbell, Kristin V., Baker, David
Publicado 2021

Precisely patterned nanofibres made from extendable protein multiplexes

por Bethel, Neville P., Borst, Andrew J., Parmeggiani, Fabio, Bick, Matthew J., Brunette, TJ, Nguyen, Hannah, Kang, Alex, Bera, Asim K., Carter, Lauren, Miranda, Marcos C., Kibler, Ryan D., Lamb, Mila, Li, Xinting, Sankaran, Banumathi, Baker, David
Publicado 2023

De novo design of a fluorescence-activating β-barrel

por Dou, Jiayi, Vorobieva, Anastassia A., Sheffler, William, Doyle, Lindsey A., Park, Hahnbeom, Bick, Matthew J., Mao, Binchen, Foight, Glenna W., Lee, Min Yen, Gagnon, Lauren A., Carter, Lauren, Sankaran, Banumathi, Ovchinnikov, Sergey, Marcos, Enrique, Huang, Po-Ssu, Vaughan, Joshua C., Stoddard, Barry L., Baker, David
Publicado 2018

De novo protein design by citizen scientists

por Koepnick, Brian, Flatten, Jeff, Husain, Tamir, Ford, Alex, Silva, Daniel-Adriano, Bick, Matthew J., Bauer, Aaron, Liu, Gaohua, Ishida, Yojiro, Boykov, Alexander, Estep, Roger D., Kleinfelter, Susan, Nørgård-Solano, Toke, Wei, Linda, Players, Foldit, Montelione, Gaetano T., DiMaio, Frank, Popovic, Zoran, Khatib, Firas, Cooper, Seth, Baker, David
Publicado 2019

Design of multi-scale protein complexes by hierarchical building block fusion

por Hsia, Yang, Mout, Rubul, Sheffler, William, Edman, Natasha I., Vulovic, Ivan, Park, Young-Jun, Redler, Rachel L., Bick, Matthew J., Bera, Asim K., Courbet, Alexis, Kang, Alex, Brunette, T. J., Nattermann, Una, Tsai, Evelyn, Saleem, Ayesha, Chow, Cameron M., Ekiert, Damian, Bhabha, Gira, Veesler, David, Baker, David
Publicado 2021

Tailored design of protein nanoparticle scaffolds for multivalent presentation of viral glycoprotein antigens

por Ueda, George, Antanasijevic, Aleksandar, Fallas, Jorge A, Sheffler, William, Copps, Jeffrey, Ellis, Daniel, Hutchinson, Geoffrey B, Moyer, Adam, Yasmeen, Anila, Tsybovsky, Yaroslav, Park, Young-Jun, Bick, Matthew J, Sankaran, Banumathi, Gillespie, Rebecca A, Brouwer, Philip JM, Zwart, Peter H, Veesler, David, Kanekiyo, Masaru, Graham, Barney S, Sanders, Rogier W, Moore, John P, Klasse, Per Johan, Ward, Andrew B, King, Neil P, Baker, David
Publicado 2020

Computational Design of Transmembrane Pores

por Xu, Chunfu, Lu, Peilong, El-Din, Tamer M. Gamal, Pei, Xue Y., Johnson, Matthew C., Uyeda, Atsuko, Bick, Matthew J., Xu, Qi, Jiang, Daohua, Bai, Hua, Reggiano, Gabriella, Hsia, Yang, Brunette, TJ, Dou, Jiayi, Ma, Dan, Lynch, Eric, Boyken, Scott E., Huang, Po-Ssu, Stewart, Lance, DiMaio, Frank, Kollman, Justin M., Luisi, Ben F., Matsuura, Tomoaki, Catterall, William A., Baker, David
Publicado 2020

Accurate de novo design of membrane-traversing macrocycles

por Bhardwaj, Gaurav, O’Connor, Jacob, Rettie, Stephen, Huang, Yen-Hua, Ramelot, Theresa A., Mulligan, Vikram Khipple, Alpkilic, Gizem Gokce, Palmer, Jonathan, Bera, Asim K., Bick, Matthew J., Di Piazza, Maddalena, Li, Xinting, Hosseinzadeh, Parisa, Craven, Timothy W., Tejero, Roberto, Lauko, Anna, Choi, Ryan, Glynn, Calina, Dong, Linlin, Griffin, Robert, van Voorhis, Wesley C., Rodriguez, Jose, Stewart, Lance, Montelione, Gaetano T., Craik, David, Baker, David
Publicado 2022