Role of transcript and interplay between transcription and replication in triplet-repeat instability in mammalian cells

por Rindler, Paul M., Bidichandani, Sanjay I.
Publicado 2011

Repair of DNA double-strand breaks within the (GAA•TTC)(n) sequence results in frequent deletion of the triplet-repeat sequence

por Pollard, Laura M., Bourn, Rebecka L., Bidichandani, Sanjay I.
Publicado 2008

Altered Nucleosome Positioning at the Transcription Start Site and Deficient Transcriptional Initiation in Friedreich Ataxia

por Chutake, Yogesh K., Costello, Whitney N., Lam, Christina, Bidichandani, Sanjay I.
Publicado 2014

Deficiency of RecA-dependent RecFOR and RecBCD pathways causes increased instability of the (GAA·TTC)(n) sequence when GAA is the lagging strand template

por Pollard, Laura M., Chutake, Yogesh K., Rindler, Paul M., Bidichandani, Sanjay I.
Publicado 2007

Epigenetic Silencing in Friedreich Ataxia Is Associated with Depletion of CTCF (CCCTC-Binding Factor) and Antisense Transcription

por De Biase, Irene, Chutake, Yogesh K., Rindler, Paul M., Bidichandani, Sanjay I.
Publicado 2009

Epigenetic Heterogeneity in Friedreich Ataxia Underlies Variable FXN Reactivation

por Rodden, Layne N., Gilliam, Kaitlyn M., Lam, Christina, Lynch, David R., Bidichandani, Sanjay I.
Publicado 2021

Replication in mammalian cells recapitulates the locus-specific differences in somatic instability of genomic GAA triplet-repeats

por M. Rindler, Paul, Clark, Rhonda M., Pollard, Laura M., De Biase, Irene, Bidichandani, Sanjay I.
Publicado 2006

Reversal of epigenetic promoter silencing in Friedreich ataxia by a class I histone deacetylase inhibitor

por Chutake, Yogesh K., Lam, Christina C., Costello, Whitney N., Anderson, Michael P., Bidichandani, Sanjay I.
Publicado 2016

FXN gene methylation determines carrier status in Friedreich ataxia

por Lam, Christina, Gilliam, Kaitlyn M, Rodden, Layne N, Schadt, Kimberly A, Lynch, David R, Bidichandani, Sanjay
Publicado 2023

Pms2 Suppresses Large Expansions of the (GAA·TTC)(n) Sequence in Neuronal Tissues

por Bourn, Rebecka L., De Biase, Irene, Pinto, Ricardo Mouro, Sandi, Chiranjeevi, Al-Mahdawi, Sahar, Pook, Mark A., Bidichandani, Sanjay I.
Publicado 2012

FXN Promoter Silencing in the Humanized Mouse Model of Friedreich Ataxia

por Chutake, Yogesh K., Costello, Whitney N., Lam, Christina C., Parikh, Aniruddha C., Hughes, Tamara T., Michalopulos, Michael G., Pook, Mark A., Bidichandani, Sanjay I.
Publicado 2015

Uptake of genetic testing and long-term tumor surveillance in von Hippel-Lindau disease

por Rasmussen, Astrid, Alonso, Elisa, Ochoa, Adriana, De Biase, Irene, Familiar, Itziar, Yescas, Petra, Sosa, Ana-Luisa, Rodríguez, Yaneth, Chávez, Mireya, López-López, Marisol, Bidichandani, Sanjay I
Publicado 2010

DNA methylation in Friedreich ataxia silences expression of frataxin isoform E

por Rodden, Layne N., Gilliam, Kaitlyn M., Lam, Christina, Rojsajjakul, Teerapat, Mesaros, Clementina, Dionisi, Chiara, Pook, Mark, Pandolfo, Massimo, Lynch, David R., Blair, Ian A., Bidichandani, Sanjay I.
Publicado 2022

Methylated and unmethylated epialleles support variegated epigenetic silencing in Friedreich ataxia

por Rodden, Layne N, Chutake, Yogesh K, Gilliam, Kaitlyn, Lam, Christina, Soragni, Elisabetta, Hauser, Lauren, Gilliam, Matthew, Wiley, Graham, Anderson, Michael P, Gottesfeld, Joel M, Lynch, David R, Bidichandani, Sanjay I
Publicado 2021