Improved Diazo-Transfer Reaction for DNA-Encoded Chemistry and Its Potential Application for Macrocyclic DEL-Libraries

por Ede, Selahattin, Schenk, Mandy, Bierer, Donald, Weinmann, Hilmar, Graham, Keith
Publicado 2021

Biomimetic enantioselective synthesis of β,β-difluoro-α-amino acid derivatives

por Peng, Qiupeng, Yan, Bingjia, Li, Fangyi, Lang, Ming, Zhang, Bei, Guo, Donghui, Bierer, Donald, Wang, Jian
Publicado 2021

Construction of diverse peptide structural architectures via chemoselective peptide ligation

por Cheung, Carina Hey Pui, Xu, Jianchao, Lee, Chi Lung, Zhang, Yanfeng, Wei, Ruohan, Bierer, Donald, Huang, Xuhui, Li, Xuechen
Publicado 2021

A novel peptide stapling strategy enables the retention of ring-closing amino acid side chains for the Wnt/β-catenin signalling pathway

por Wu, Ye, Li, Ye-Hua, Li, Xiang, Zou, Yan, Liao, Hong-Li, Liu, Lei, Chen, Ye-Guang, Bierer, Donald, Hu, Hong-Gang
Publicado 2017

Cyclobutane-bearing restricted anchoring residues enabled geometry-specific hydrocarbon peptide stapling

por Chen, Baobao, Liu, Chao, Cong, Wei, Gao, Fei, Zou, Yan, Su, Li, Liu, Lei, Hillisch, Alexander, Lehmann, Lutz, Bierer, Donald, Li, Xiang, Hu, Hong-Gang
Publicado 2023

Chemical synthesis and biological activity of peptides incorporating an ether bridge as a surrogate for a disulfide bond

por Zhao, Rui, Shi, Pan, Chen, Junyou, Sun, Shuaishuai, Chen, Jingnan, Cui, Jibin, Wu, Fangming, Fang, Gemin, Tian, Changlin, Shi, Jing, Bierer, Donald, Liu, Lei, Li, Yi-Ming
Publicado 2020

Entropy of stapled peptide inhibitors in free state is the major contributor to the improvement of binding affinity with the GK domain

por Unarta, Ilona Christy, Xu, Jianchao, Shang, Yuan, Cheung, Carina Hey Pui, Zhu, Ruichi, Chen, Xudong, Cao, Siqin, Cheung, Peter Pak-Hang, Bierer, Donald, Zhang, Mingjie, Huang, Xuhui, Li, Xuechen
Publicado 2021